Detailed information NTG0972020

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC74_RS09420
• Genome accession: NZ_CP150759
• Coordinates: 1855293..1856180 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain TUM22178
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1850293..1861180

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC74_RS09390 (WOC74_09380)	-	1850312..1850404 (+)	93	WP_010956583.1	hypothetical protein	-
WOC74_RS09395 (WOC74_09385)	-	1850512..1851009 (-)	498	WP_001065268.1	glutathione peroxidase	-
WOC74_RS09400 (WOC74_09390)	-	1851019..1851279 (-)	261	WP_001791974.1	hypothetical protein	-
WOC74_RS09405 (WOC74_09395)	-	1851661..1851774 (-)	114	Protein_1822	hypothetical protein	-
WOC74_RS09410 (WOC74_09400)	-	1852433..1854433 (-)	2001	WP_368409512.1	ABC transporter permease	-
WOC74_RS09415 (WOC74_09405)	-	1854430..1855185 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC74_RS09420 (WOC74_09410)	braS	1855293..1856180 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC74_RS09425 (WOC74_09415)	braR	1856191..1856856 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC74_RS09430 (WOC74_09420)	-	1856882..1857082 (-)	201	WP_000604727.1	hypothetical protein	-
WOC74_RS09435 (WOC74_09425)	-	1857280..1858704 (+)	1425	WP_000953748.1	alkaline phosphatase	-
WOC74_RS09440	-	1858764..1858865 (-)	102	WP_000731972.1	SE2200 family small protein	-
WOC74_RS09445 (WOC74_09435)	-	1858987..1859442 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC74_RS09450 (WOC74_09440)	-	1859687..1860448 (-)	762	Protein_1831	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=972020 WOC74_RS09420 WP_000143417.1 1855293..1856180(-) (braS) [Staphylococcus aureus strain TUM22178]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=972020 WOC74_RS09420 WP_000143417.1 1855293..1856180(-) (braS) [Staphylococcus aureus strain TUM22178]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99