Detailed information NTG0971955

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC67_RS04535
• Genome accession: NZ_CP150758
• Coordinates: 944747..945634 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM22182
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 939747..950634

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC67_RS04505 (WOC67_04515)	-	940479..941240 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
WOC67_RS04510 (WOC67_04520)	-	941485..941940 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC67_RS04515 (WOC67_04525)	-	942062..942163 (+)	102	WP_000731972.1	SE2200 family small protein	-
WOC67_RS04520 (WOC67_04530)	-	942223..943647 (-)	1425	WP_000953744.1	alkaline phosphatase	-
WOC67_RS04525 (WOC67_04535)	-	943845..944045 (+)	201	WP_000604728.1	hypothetical protein	-
WOC67_RS04530 (WOC67_04540)	braR	944071..944736 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC67_RS04535 (WOC67_04545)	braS	944747..945634 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC67_RS04540 (WOC67_04550)	-	945742..946497 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC67_RS04545 (WOC67_04555)	-	946494..948494 (+)	2001	WP_000776751.1	ABC transporter permease	-
WOC67_RS04550 (WOC67_04560)	-	949153..949266 (+)	114	WP_011447078.1	hypothetical protein	-
WOC67_RS04555 (WOC67_04565)	-	949648..949908 (+)	261	WP_001789910.1	hypothetical protein	-
WOC67_RS04560 (WOC67_04570)	-	949918..950415 (+)	498	WP_001065268.1	glutathione peroxidase	-
WOC67_RS04565 (WOC67_04575)	-	950523..950615 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=971955 WOC67_RS04535 WP_000143419.1 944747..945634(+) (braS) [Staphylococcus aureus strain TUM22182]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=971955 WOC67_RS04535 WP_000143419.1 944747..945634(+) (braS) [Staphylococcus aureus strain TUM22182]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997