Detailed information NTG0971905

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC65_RS01495
• Genome accession: NZ_CP150756
• Coordinates: 342588..343475 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain TUM22188
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 337588..348475

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC65_RS01465 (WOC65_01455)	-	338320..339081 (+)	762	Protein_290	alpha/beta hydrolase	-
WOC65_RS01470 (WOC65_01460)	-	339326..339781 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC65_RS01475 (WOC65_01465)	-	339903..340004 (+)	102	WP_000731972.1	SE2200 family small protein	-
WOC65_RS01480 (WOC65_01470)	-	340064..341488 (-)	1425	WP_000953748.1	alkaline phosphatase	-
WOC65_RS01485 (WOC65_01475)	-	341686..341886 (+)	201	WP_000604727.1	hypothetical protein	-
WOC65_RS01490 (WOC65_01480)	braR	341912..342577 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC65_RS01495 (WOC65_01485)	braS	342588..343475 (+)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC65_RS01500 (WOC65_01490)	-	343583..344338 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC65_RS01505 (WOC65_01495)	-	344335..346335 (+)	2001	WP_368409512.1	ABC transporter permease	-
WOC65_RS01510 (WOC65_01500)	-	346994..347107 (+)	114	Protein_299	hypothetical protein	-
WOC65_RS01515 (WOC65_01505)	-	347489..347749 (+)	261	WP_001791974.1	hypothetical protein	-
WOC65_RS01520 (WOC65_01510)	-	347759..348256 (+)	498	WP_001065268.1	glutathione peroxidase	-
WOC65_RS01525 (WOC65_01515)	-	348364..348456 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=971905 WOC65_RS01495 WP_000143417.1 342588..343475(+) (braS) [Staphylococcus aureus strain TUM22188]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=971905 WOC65_RS01495 WP_000143417.1 342588..343475(+) (braS) [Staphylococcus aureus strain TUM22188]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99