Detailed information NTG0971893

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: WOC71_RS13370
• Genome accession: NZ_CP150754
• Coordinates: 2665409..2666452 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM22457
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2660409..2671452

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC71_RS13340 (WOC71_13325)	-	2660835..2660945 (+)	111	WP_001790257.1	hypothetical protein	-
WOC71_RS13345 (WOC71_13330)	-	2660974..2661387 (+)	414	WP_001557448.1	hypothetical protein	-
WOC71_RS13350 (WOC71_13335)	-	2661818..2662804 (-)	987	WP_406818741.1	FUSC family protein	-
WOC71_RS13355 (WOC71_13340)	map	2663335..2664093 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
WOC71_RS13360 (WOC71_13345)	-	2664310..2664696 (+)	387	WP_001110179.1	hypothetical protein	-
WOC71_RS13365 (WOC71_13350)	liaF	2664711..2665412 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
WOC71_RS13370 (WOC71_13355)	vraS	2665409..2666452 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
WOC71_RS13375 (WOC71_13360)	vraR	2666442..2667071 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
WOC71_RS13380 (WOC71_13365)	-	2667184..2668401 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
WOC71_RS13385 (WOC71_13370)	-	2668679..2668954 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
WOC71_RS13390 (WOC71_13375)	-	2668961..2669425 (-)	465	WP_042109418.1	low molecular weight protein-tyrosine-phosphatase	-
WOC71_RS13395 (WOC71_13380)	-	2669572..2669772 (+)	201	WP_000180460.1	DUF1128 family protein	-
WOC71_RS13400 (WOC71_13385)	-	2669775..2671031 (+)	1257	WP_001795108.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=971893 WOC71_RS13370 WP_001017131.1 2665409..2666452(+) (vraS) [Staphylococcus aureus strain TUM22457]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=971893 WOC71_RS13370 WP_001017131.1 2665409..2666452(+) (vraS) [Staphylococcus aureus strain TUM22457]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1