Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | WOC71_RS08890 | Genome accession | NZ_CP150754 |
| Coordinates | 1760977..1762605 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain TUM22457 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 1714444..1763976 | 1760977..1762605 | within | 0 |
Gene organization within MGE regions
Location: 1714444..1763976
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| WOC71_RS08660 (WOC71_08650) | ccrC | 1714444..1716123 (+) | 1680 | WP_368409903.1 | cassette chromosome recombinase CcrC | - |
| WOC71_RS08665 (WOC71_08655) | - | 1716212..1716550 (+) | 339 | WP_032604336.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| WOC71_RS08670 (WOC71_08660) | - | 1716644..1716956 (+) | 313 | Protein_1712 | DUF960 family protein | - |
| WOC71_RS08675 (WOC71_08665) | - | 1716972..1717475 (+) | 504 | WP_002437518.1 | DUF1643 domain-containing protein | - |
| WOC71_RS08680 (WOC71_08670) | - | 1717489..1717710 (+) | 222 | WP_002437519.1 | hypothetical protein | - |
| WOC71_RS08685 (WOC71_08675) | - | 1717925..1718491 (+) | 567 | WP_002437520.1 | hypothetical protein | - |
| WOC71_RS08690 (WOC71_08680) | - | 1718569..1721688 (-) | 3120 | WP_368409904.1 | type I restriction endonuclease subunit R | - |
| WOC71_RS08695 (WOC71_08685) | - | 1721672..1722973 (-) | 1302 | WP_000456234.1 | restriction endonuclease subunit S | - |
| WOC71_RS08700 (WOC71_08690) | - | 1722963..1724477 (-) | 1515 | WP_406818716.1 | type I restriction-modification system subunit M | - |
| WOC71_RS08705 (WOC71_08695) | - | 1724886..1726982 (+) | 2097 | WP_223200550.1 | ATP-dependent endonuclease | - |
| WOC71_RS08710 (WOC71_08700) | - | 1726984..1728732 (+) | 1749 | WP_406818717.1 | UvrD-helicase domain-containing protein | - |
| WOC71_RS08715 (WOC71_08705) | - | 1728942..1729124 (+) | 183 | Protein_1721 | MFS transporter | - |
| WOC71_RS08720 (WOC71_08710) | - | 1729192..1730610 (-) | 1419 | WP_032605060.1 | aspartate aminotransferase family protein | - |
| WOC71_RS08725 (WOC71_08715) | - | 1731561..1731728 (+) | 168 | WP_000669688.1 | hypothetical protein | - |
| WOC71_RS08730 (WOC71_08720) | - | 1732203..1733459 (+) | 1257 | WP_000566670.1 | MrcB family domain-containing protein | - |
| WOC71_RS08735 (WOC71_08725) | - | 1733874..1734113 (+) | 240 | WP_001282728.1 | hypothetical protein | - |
| WOC71_RS08740 (WOC71_08730) | - | 1734145..1734819 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| WOC71_RS08745 (WOC71_08735) | - | 1734910..1735893 (-) | 984 | Protein_1727 | protein rep | - |
| WOC71_RS08750 (WOC71_08740) | mobV | 1736138..1737391 (-) | 1254 | WP_368409905.1 | MobV family relaxase | - |
| WOC71_RS08755 (WOC71_08745) | bleO | 1737897..1738301 (-) | 405 | WP_001242578.1 | bleomycin binding protein | - |
| WOC71_RS08760 (WOC71_08750) | aadD1 | 1738518..1739288 (-) | 771 | WP_001795128.1 | aminoglycoside O-nucleotidyltransferase ANT(4')-Ia | - |
| WOC71_RS08765 (WOC71_08755) | - | 1739481..1740155 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| WOC71_RS08770 (WOC71_08760) | - | 1740239..1740580 (+) | 342 | WP_001797647.1 | hydroxymethylglutaryl-CoA synthase | - |
| WOC71_RS08775 (WOC71_08765) | - | 1741297..1742040 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| WOC71_RS08780 (WOC71_08770) | - | 1742137..1742565 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| WOC71_RS08785 (WOC71_08775) | mecA | 1742611..1744620 (-) | 2010 | WP_218089213.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| WOC71_RS08790 (WOC71_08780) | mecR1 | 1744717..1746474 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| WOC71_RS08795 (WOC71_08785) | mecI | 1746474..1746845 (+) | 372 | WP_406818718.1 | mecA-type methicillin resistance repressor MecI | - |
| WOC71_RS08800 (WOC71_08790) | psm-mec | 1746930..1746998 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| WOC71_RS08805 (WOC71_08795) | - | 1747353..1748462 (+) | 1110 | WP_000943131.1 | ROK family transcriptional regulator | - |
| WOC71_RS08810 (WOC71_08800) | cstB | 1748576..1749910 (-) | 1335 | Protein_1740 | persulfide dioxygenase-sulfurtransferase CstB | - |
| WOC71_RS08815 (WOC71_08805) | - | 1749943..1751007 (-) | 1065 | WP_406818719.1 | DsrE/DsrF/DrsH-like family protein | - |
| WOC71_RS08820 (WOC71_08810) | cstR | 1751143..1751403 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| WOC71_RS08825 (WOC71_08815) | - | 1751403..1752041 (+) | 639 | Protein_1743 | sulfite exporter TauE/SafE family protein | - |
| WOC71_RS08830 | - | 1752095..1752154 (-) | 60 | Protein_1744 | DNA repair protein RadC | - |
| WOC71_RS08835 (WOC71_08820) | - | 1752386..1753048 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| WOC71_RS08840 | - | 1753440..1753499 (+) | 60 | WP_010959190.1 | erythromycin resistance leader peptide | - |
| WOC71_RS08845 (WOC71_08825) | erm(A) | 1753582..1754313 (+) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| WOC71_RS08850 (WOC71_08830) | - | 1754439..1755221 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| WOC71_RS08855 (WOC71_08835) | - | 1755372..1755749 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| WOC71_RS08860 (WOC71_08840) | - | 1755756..1757648 (-) | 1893 | WP_368409847.1 | site-specific integrase | - |
| WOC71_RS08865 (WOC71_08845) | - | 1757645..1758730 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| WOC71_RS08870 (WOC71_08850) | - | 1758849..1759166 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| WOC71_RS08875 (WOC71_08855) | - | 1759187..1759693 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| WOC71_RS08880 (WOC71_08860) | - | 1759711..1760022 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| WOC71_RS08885 (WOC71_08865) | - | 1760109..1760459 (-) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| WOC71_RS08890 (WOC71_08870) | ccrB | 1760977..1762605 (-) | 1629 | WP_001186602.1 | cassette chromosome recombinase CcrB | Machinery gene |
| WOC71_RS08895 (WOC71_08875) | ccrA | 1762627..1763976 (-) | 1350 | WP_000815646.1 | cassette chromosome recombinase CcrA | Machinery gene |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=971885 WOC71_RS08890 WP_001186602.1 1760977..1762605(-) (ccrB) [Staphylococcus aureus strain TUM22457]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=971885 WOC71_RS08890 WP_001186602.1 1760977..1762605(-) (ccrB) [Staphylococcus aureus strain TUM22457]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |