Detailed information NTG0971881

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC71_RS08015
• Genome accession: NZ_CP150754
• Coordinates: 1560059..1560946 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain TUM22457
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1555059..1565946

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC71_RS07985 (WOC71_07980)	-	1555078..1555170 (+)	93	WP_010956583.1	hypothetical protein	-
WOC71_RS07990 (WOC71_07985)	-	1555278..1555775 (-)	498	WP_001065268.1	glutathione peroxidase	-
WOC71_RS07995 (WOC71_07990)	-	1555785..1556045 (-)	261	WP_001791974.1	hypothetical protein	-
WOC71_RS08000 (WOC71_07995)	-	1556427..1556540 (-)	114	Protein_1580	hypothetical protein	-
WOC71_RS08005 (WOC71_08000)	-	1557199..1559199 (-)	2001	WP_000776751.1	ABC transporter permease	-
WOC71_RS08010 (WOC71_08005)	-	1559196..1559951 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC71_RS08015 (WOC71_08010)	braS	1560059..1560946 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC71_RS08020 (WOC71_08015)	braR	1560957..1561622 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC71_RS08025 (WOC71_08020)	-	1561648..1561848 (-)	201	WP_000604730.1	hypothetical protein	-
WOC71_RS08030 (WOC71_08025)	-	1562046..1563470 (+)	1425	WP_000953755.1	alkaline phosphatase	-
WOC71_RS08035	-	1563530..1563631 (-)	102	WP_000731976.1	SE2200 family small protein	-
WOC71_RS08040 (WOC71_08035)	-	1563753..1564208 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC71_RS08045 (WOC71_08040)	-	1564453..1565214 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=971881 WOC71_RS08015 WP_000143425.1 1560059..1560946(-) (braS) [Staphylococcus aureus strain TUM22457]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=971881 WOC71_RS08015 WP_000143425.1 1560059..1560946(-) (braS) [Staphylococcus aureus strain TUM22457]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1