Detailed information NTG0971740

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC43_RS04730
• Genome accession: NZ_CP150749
• Coordinates: 995126..996013 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM22699
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 990126..1001013

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC43_RS04700 (WOC43_04705)	-	990858..991619 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
WOC43_RS04705 (WOC43_04710)	-	991864..992319 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC43_RS04710 (WOC43_04715)	-	992441..992542 (+)	102	WP_000731972.1	SE2200 family small protein	-
WOC43_RS04715 (WOC43_04720)	-	992602..994026 (-)	1425	WP_000953744.1	alkaline phosphatase	-
WOC43_RS04720 (WOC43_04725)	-	994224..994424 (+)	201	WP_000604732.1	hypothetical protein	-
WOC43_RS04725 (WOC43_04730)	braR	994450..995115 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC43_RS04730 (WOC43_04735)	braS	995126..996013 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC43_RS04735 (WOC43_04740)	-	996121..996876 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC43_RS04740 (WOC43_04745)	-	996873..998873 (+)	2001	WP_000776751.1	ABC transporter permease	-
WOC43_RS04745 (WOC43_04750)	-	999532..999645 (+)	114	WP_011447078.1	hypothetical protein	-
WOC43_RS04750 (WOC43_04755)	-	1000027..1000287 (+)	261	WP_001789910.1	hypothetical protein	-
WOC43_RS04755 (WOC43_04760)	-	1000297..1000794 (+)	498	WP_001065268.1	glutathione peroxidase	-
WOC43_RS04760 (WOC43_04765)	-	1000902..1000994 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=971740 WOC43_RS04730 WP_000143419.1 995126..996013(+) (braS) [Staphylococcus aureus strain TUM22699]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=971740 WOC43_RS04730 WP_000143419.1 995126..996013(+) (braS) [Staphylococcus aureus strain TUM22699]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997