Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | WOC70_RS06690 | Genome accession | NZ_CP150742 |
| Coordinates | 1383264..1384613 (+) | Length | 449 a.a. |
| NCBI ID | WP_000815646.1 | Uniprot ID | Q9XB96 |
| Organism | Staphylococcus aureus strain TUM22707 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1347760..1391484 | 1383264..1384613 | within | 0 |
| SCCmec | 1383264..1404604 | 1383264..1384613 | within | 0 |
Gene organization within MGE regions
Location: 1347760..1404604
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| WOC70_RS06535 (WOC70_06535) | - | 1347760..1350912 (-) | 3153 | WP_000080564.1 | DEAD/DEAH box helicase | - |
| WOC70_RS06540 (WOC70_06540) | - | 1351179..1351781 (-) | 603 | WP_000908956.1 | hypothetical protein | - |
| WOC70_RS06545 (WOC70_06545) | - | 1351989..1352285 (-) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| WOC70_RS06550 (WOC70_06550) | - | 1352334..1352537 (-) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| WOC70_RS06555 (WOC70_06555) | - | 1352846..1353832 (+) | 987 | WP_000662022.1 | tRNA-dihydrouridine synthase | - |
| WOC70_RS06560 (WOC70_06560) | - | 1354018..1354232 (+) | 215 | Protein_1289 | universal stress protein | - |
| WOC70_RS06565 (WOC70_06565) | sqr | 1354499..1355692 (-) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| WOC70_RS06570 (WOC70_06570) | cstB | 1355711..1357045 (-) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| WOC70_RS06575 (WOC70_06575) | cstA | 1357076..1358140 (-) | 1065 | WP_000816133.1 | persulfide response sulfurtransferase CstA | - |
| WOC70_RS06580 (WOC70_06580) | cstR | 1358277..1358537 (+) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| WOC70_RS06585 (WOC70_06585) | - | 1358537..1359292 (+) | 756 | WP_031794076.1 | sulfite exporter TauE/SafE family protein | - |
| WOC70_RS06590 (WOC70_06590) | - | 1359390..1359478 (+) | 89 | Protein_1295 | hypothetical protein | - |
| WOC70_RS06595 (WOC70_06595) | - | 1359783..1360138 (+) | 356 | Protein_1296 | tRNA-dihydrouridine synthase | - |
| WOC70_RS06600 (WOC70_06600) | - | 1360236..1361981 (-) | 1746 | WP_000700190.1 | DUF6119 family protein | - |
| WOC70_RS06605 (WOC70_06605) | - | 1362128..1362220 (-) | 93 | WP_001790000.1 | hypothetical protein | - |
| WOC70_RS06610 (WOC70_06610) | - | 1362184..1362318 (+) | 135 | WP_001790628.1 | hypothetical protein | - |
| WOC70_RS06615 (WOC70_06615) | - | 1362568..1364076 (-) | 1509 | WP_341262107.1 | protein kinase | - |
| WOC70_RS06620 (WOC70_06620) | - | 1364191..1364817 (+) | 627 | WP_001176969.1 | hypothetical protein | - |
| WOC70_RS06625 (WOC70_06625) | - | 1365936..1366832 (+) | 897 | WP_000411461.1 | DUF927 domain-containing protein | - |
| WOC70_RS06630 (WOC70_06630) | - | 1366842..1367711 (+) | 870 | WP_000626133.1 | hypothetical protein | - |
| WOC70_RS06635 (WOC70_06635) | - | 1368256..1368812 (-) | 557 | Protein_1304 | K(+)-transporting ATPase subunit C | - |
| WOC70_RS06640 (WOC70_06640) | - | 1368828..1370849 (-) | 2022 | WP_000852430.1 | K(+)-transporting ATPase subunit B | - |
| WOC70_RS06645 (WOC70_06645) | kdpA | 1370868..1372544 (-) | 1677 | WP_000029430.1 | potassium-transporting ATPase subunit KdpA | - |
| WOC70_RS06650 (WOC70_06650) | kdpF | 1372565..1372645 (-) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| WOC70_RS06655 (WOC70_06655) | - | 1372812..1375481 (+) | 2670 | WP_000446429.1 | sensor histidine kinase KdpD | - |
| WOC70_RS06660 (WOC70_06660) | - | 1375456..1376151 (+) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| WOC70_RS06665 (WOC70_06665) | - | 1376873..1377799 (+) | 927 | Protein_1310 | YfcC family protein | - |
| WOC70_RS06670 (WOC70_06670) | - | 1378310..1379451 (+) | 1142 | Protein_1311 | IS3-like element ISSau4 family transposase | - |
| WOC70_RS06675 (WOC70_06675) | - | 1379702..1380748 (+) | 1047 | WP_001060127.1 | hypothetical protein | - |
| WOC70_RS06680 (WOC70_06680) | - | 1380941..1381237 (+) | 297 | WP_000273824.1 | single-stranded DNA-binding protein | - |
| WOC70_RS06685 (WOC70_06685) | - | 1381237..1383030 (+) | 1794 | WP_000195100.1 | DUF927 domain-containing protein | - |
| WOC70_RS06690 (WOC70_06690) | ccrA | 1383264..1384613 (+) | 1350 | WP_000815646.1 | recombinase family protein | Machinery gene |
| WOC70_RS06695 (WOC70_06695) | ccrB | 1384635..1386263 (+) | 1629 | WP_001186602.1 | recombinase family protein | Machinery gene |
| WOC70_RS06700 (WOC70_06700) | - | 1386781..1387131 (+) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| WOC70_RS06705 (WOC70_06705) | - | 1387218..1387529 (+) | 312 | WP_000700853.1 | DUF960 family protein | - |
| WOC70_RS06710 (WOC70_06710) | - | 1387547..1388053 (+) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| WOC70_RS06715 (WOC70_06715) | - | 1388074..1388391 (+) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| WOC70_RS06720 (WOC70_06720) | - | 1388510..1389595 (+) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| WOC70_RS06725 (WOC70_06725) | - | 1389592..1391484 (+) | 1893 | WP_001557544.1 | site-specific integrase | - |
| WOC70_RS06730 (WOC70_06730) | - | 1391491..1391868 (+) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| WOC70_RS06735 (WOC70_06735) | - | 1392019..1392801 (+) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| WOC70_RS06740 (WOC70_06740) | erm(A) | 1392927..1393658 (-) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| WOC70_RS06745 (WOC70_06745) | - | 1394167..1394829 (+) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| WOC70_RS06750 (WOC70_06750) | - | 1395174..1395812 (-) | 639 | Protein_1327 | sulfite exporter TauE/SafE family protein | - |
| WOC70_RS06755 (WOC70_06755) | cstR | 1395812..1396072 (-) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| WOC70_RS06760 (WOC70_06760) | - | 1396208..1397272 (+) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| WOC70_RS06765 (WOC70_06765) | cstB | 1397305..1398639 (+) | 1335 | Protein_1330 | persulfide dioxygenase-sulfurtransferase CstB | - |
| WOC70_RS06770 (WOC70_06770) | - | 1398753..1399862 (-) | 1110 | WP_000943131.1 | ROK family transcriptional regulator | - |
| WOC70_RS06775 (WOC70_06775) | psm-mec | 1400217..1400285 (+) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| WOC70_RS06780 (WOC70_06780) | mecI | 1400370..1400741 (-) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| WOC70_RS06785 (WOC70_06785) | mecR1 | 1400741..1402498 (-) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| WOC70_RS06790 (WOC70_06790) | mecA | 1402595..1404604 (+) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
Sequence
Protein
Download Length: 449 a.a. Molecular weight: 52607.20 Da Isoelectric Point: 9.9585
>NTDB_id=971561 WOC70_RS06690 WP_000815646.1 1383264..1384613(+) (ccrA) [Staphylococcus aureus strain TUM22707]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGAFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQIKQTSSDNQLKQKIKCPCCNTTLTNMTVRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CKDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGAFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQIKQTSSDNQLKQKIKCPCCNTTLTNMTVRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CKDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA
Nucleotide
Download Length: 1350 bp
>NTDB_id=971561 WOC70_RS06690 WP_000815646.1 1383264..1384613(+) (ccrA) [Staphylococcus aureus strain TUM22707]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAGGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACGCAATTAATTCAACAAGGGCAATGTGACATATTATGTTGTTATCGTCTTAATAGATTACATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATACCATGTTCATATCTTAAGCGTACACGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGAATATCAC
AACGGAGCATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAATCAAACAGACATCTTCGGATAACCAACTAAAACAAAAAATCAA
ATGCCCATGTTGTAATACAACACTTACGAATATGACCGTTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCTCGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCAAAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGACATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCGATTGCATAA
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAGGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACGCAATTAATTCAACAAGGGCAATGTGACATATTATGTTGTTATCGTCTTAATAGATTACATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATACCATGTTCATATCTTAAGCGTACACGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGAATATCAC
AACGGAGCATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAATCAAACAGACATCTTCGGATAACCAACTAAAACAAAAAATCAA
ATGCCCATGTTGTAATACAACACTTACGAATATGACCGTTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCTCGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCAAAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGACATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCGATTGCATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus N315 |
100 |
100 |
1 |
| ccrA | Staphylococcus aureus COL |
74.833 |
100 |
0.748 |