Detailed information NTG0971510

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC52_RS04450
• Genome accession: NZ_CP150739
• Coordinates: 823261..824148 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM22721
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 818261..829148

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC52_RS04420 (WOC52_04420)	-	818280..818372 (+)	93	WP_010956583.1	hypothetical protein	-
WOC52_RS04425 (WOC52_04425)	-	818480..818977 (-)	498	WP_001065268.1	glutathione peroxidase	-
WOC52_RS04430 (WOC52_04430)	-	818987..819247 (-)	261	WP_001789910.1	hypothetical protein	-
WOC52_RS04435 (WOC52_04435)	-	819629..819742 (-)	114	WP_011447078.1	hypothetical protein	-
WOC52_RS04440 (WOC52_04440)	-	820401..822401 (-)	2001	WP_000776751.1	ABC transporter permease	-
WOC52_RS04445 (WOC52_04445)	-	822398..823153 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC52_RS04450 (WOC52_04450)	braS	823261..824148 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC52_RS04455 (WOC52_04455)	braR	824159..824824 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC52_RS04460 (WOC52_04460)	-	824850..825050 (-)	201	WP_000604728.1	hypothetical protein	-
WOC52_RS04465 (WOC52_04465)	-	825248..826672 (+)	1425	WP_000953744.1	alkaline phosphatase	-
WOC52_RS04470 (WOC52_04470)	-	826742..826852 (+)	111	WP_001791296.1	hypothetical protein	-
WOC52_RS04475 (WOC52_04475)	-	826955..827410 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC52_RS04480 (WOC52_04480)	-	827655..828416 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=971510 WOC52_RS04450 WP_000143419.1 823261..824148(-) (braS) [Staphylococcus aureus strain TUM22721]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=971510 WOC52_RS04450 WP_000143419.1 823261..824148(-) (braS) [Staphylococcus aureus strain TUM22721]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997