Detailed information NTG0971502

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC44_RS12535
• Genome accession: NZ_CP150737
• Coordinates: 2513668..2514555 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM22723
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2508668..2519555

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC44_RS12505 (WOC44_12505)	-	2509400..2510161 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
WOC44_RS12510 (WOC44_12510)	-	2510406..2510861 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC44_RS12515 (WOC44_12515)	-	2510983..2511084 (+)	102	WP_000731972.1	SE2200 family small protein	-
WOC44_RS12520 (WOC44_12520)	-	2511144..2512568 (-)	1425	WP_000953744.1	alkaline phosphatase	-
WOC44_RS12525 (WOC44_12525)	-	2512766..2512966 (+)	201	WP_000604728.1	hypothetical protein	-
WOC44_RS12530 (WOC44_12530)	braR	2512992..2513657 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC44_RS12535 (WOC44_12535)	braS	2513668..2514555 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC44_RS12540 (WOC44_12540)	-	2514663..2515418 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC44_RS12545 (WOC44_12545)	-	2515415..2517415 (+)	2001	WP_000776751.1	ABC transporter permease	-
WOC44_RS12550 (WOC44_12550)	-	2518074..2518187 (+)	114	WP_011447078.1	hypothetical protein	-
WOC44_RS12555 (WOC44_12555)	-	2518569..2518829 (+)	261	WP_001789910.1	hypothetical protein	-
WOC44_RS12560 (WOC44_12560)	-	2518839..2519336 (+)	498	WP_001065268.1	glutathione peroxidase	-
WOC44_RS12565 (WOC44_12565)	-	2519444..2519536 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=971502 WOC44_RS12535 WP_000143419.1 2513668..2514555(+) (braS) [Staphylococcus aureus strain TUM22723]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=971502 WOC44_RS12535 WP_000143419.1 2513668..2514555(+) (braS) [Staphylococcus aureus strain TUM22723]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997