Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   WOC73_RS11705 Genome accession   NZ_CP150735
Coordinates   2315357..2316985 (-) Length   542 a.a.
NCBI ID   WP_341261357.1    Uniprot ID   -
Organism   Staphylococcus aureus strain TUM22730     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 2308579..2323537 2315357..2316985 within 0


Gene organization within MGE regions


Location: 2308579..2323537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WOC73_RS11670 (WOC73_11670) mecA 2308579..2310588 (-) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  WOC73_RS11675 (WOC73_11675) - 2310685..2311671 (+) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  WOC73_RS11680 (WOC73_11680) - 2311643..2311903 (+) 261 WP_001549961.1 type I restriction enzyme endonuclease domain-containing protein -
  WOC73_RS11685 (WOC73_11685) - 2311913..2313514 (-) 1602 Protein_2259 IS1182 family transposase -
  WOC73_RS11690 (WOC73_11690) - 2313566..2314072 (-) 507 WP_001092189.1 DUF1643 domain-containing protein -
  WOC73_RS11695 (WOC73_11695) - 2314087..2314398 (-) 312 WP_000700851.1 DUF960 family protein -
  WOC73_RS11700 (WOC73_11700) - 2314485..2314835 (-) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  WOC73_RS11705 (WOC73_11705) ccrB 2315357..2316985 (-) 1629 WP_341261357.1 recombinase family protein Machinery gene
  WOC73_RS11710 (WOC73_11710) ccrA 2317007..2318356 (-) 1350 WP_000815640.1 recombinase family protein Machinery gene
  WOC73_RS11715 (WOC73_11715) - 2318590..2320383 (-) 1794 WP_000079473.1 DUF927 domain-containing protein -
  WOC73_RS11720 (WOC73_11720) - 2320383..2320679 (-) 297 WP_000273823.1 single-stranded DNA-binding protein -
  WOC73_RS11725 (WOC73_11725) - 2320872..2321928 (-) 1057 Protein_2267 hypothetical protein -
  WOC73_RS11730 (WOC73_11730) - 2322383..2323537 (+) 1155 WP_000912116.1 ATP-binding protein -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62653.85 Da        Isoelectric Point: 9.8371

>NTDB_id=971457 WOC73_RS11705 WP_341261357.1 2315357..2316985(-) (ccrB) [Staphylococcus aureus strain TUM22730]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRMLKDAKEGNINCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFECYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKINNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKTLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=971457 WOC73_RS11705 WP_341261357.1 2315357..2316985(-) (ccrB) [Staphylococcus aureus strain TUM22730]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAACAGACCTGAGCTCCAACGTATGTTGAAAGATGCAAAAGAAGGCAATATCAACTGTGTTATG
GTATACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTGTCAGAGCGTATGGAAGTCAATACTTCTTCTGGTAAACTCATGTTACAGATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAACGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTACCACTAGGTTATGACAAAATACCAGATAGTAAACACGAGCTAATGATTAACCAACATGAAGCTAATATTGTAAAATA
TATATTCGAGTGCTATGCCAAAGGACATGGCTATCGTAAAATTGCCAATGCATTGAATCACAAAGGATATGTCACTAAAA
AGGGGAAACCTTTCAGTATTAGTTCAATCACATACATCTTAGCTAACCCTTTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTGAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAGAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACTCTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAAATAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGACTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATTAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTATTTT
TGCCCCAAACACTATATCTTACTATTTAG

Domains

Predicted by InterproScan.

Ogr/Delta-like zinc finger (Ogr_Delta)

(301-356)

Recombinase (Recombinase)

(180-280)

Resolvase, N terminal domain (Resolvase)

(11-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

98.708

100

0.987

Multiple sequence alignment