Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   WOC73_RS07970 Genome accession   NZ_CP150735
Coordinates   1557803..1558519 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain TUM22730     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1552803..1563519
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WOC73_RS07940 (WOC73_07940) - 1553023..1553649 (+) 627 WP_000522384.1 nitroreductase family protein -
  WOC73_RS07945 (WOC73_07945) - 1554010..1554795 (+) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  WOC73_RS07950 (WOC73_07950) hld 1555391..1555471 (-) 81 WP_000046022.1 delta-hemolysin -
  WOC73_RS07955 (WOC73_07955) agrB 1555761..1556330 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  WOC73_RS07960 (WOC73_07960) - 1556327..1556467 (+) 141 WP_341261344.1 cyclic lactone autoinducer peptide -
  WOC73_RS07965 (WOC73_07965) - 1556492..1557784 (+) 1293 WP_001657119.1 GHKL domain-containing protein -
  WOC73_RS07970 (WOC73_07970) agrA 1557803..1558519 (+) 717 WP_000688498.1 LytTR family DNA-binding domain-containing protein Regulator
  WOC73_RS07975 (WOC73_07975) - 1558591..1558700 (+) 110 Protein_1533 hypothetical protein -
  WOC73_RS07980 (WOC73_07980) - 1558888..1559847 (-) 960 WP_001253302.1 carbohydrate kinase -
  WOC73_RS07985 (WOC73_07985) - 1559844..1561328 (-) 1485 WP_000141426.1 sucrose-6-phosphate hydrolase -
  WOC73_RS07990 (WOC73_07990) - 1561477..1562427 (-) 951 WP_000790318.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=971449 WOC73_RS07970 WP_000688498.1 1557803..1558519(+) (agrA) [Staphylococcus aureus strain TUM22730]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=971449 WOC73_RS07970 WP_000688498.1 1557803..1558519(+) (agrA) [Staphylococcus aureus strain TUM22730]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment