Detailed information NTG0971447

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: WOC73_RS07125
• Genome accession: NZ_CP150735
• Coordinates: 1422328..1423371 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM22730
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1417328..1428371

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC73_RS07095 (WOC73_07095)	-	1417750..1419006 (-)	1257	WP_001793428.1	aminopeptidase	-
WOC73_RS07100 (WOC73_07100)	-	1419009..1419209 (-)	201	WP_000180463.1	DUF1128 family protein	-
WOC73_RS07105 (WOC73_07105)	-	1419356..1419820 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
WOC73_RS07110 (WOC73_07110)	-	1419827..1420102 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
WOC73_RS07115 (WOC73_07115)	-	1420380..1421597 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
WOC73_RS07120 (WOC73_07120)	vraR	1421709..1422338 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
WOC73_RS07125 (WOC73_07125)	vraS	1422328..1423371 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
WOC73_RS07130 (WOC73_07130)	liaF	1423368..1424069 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
WOC73_RS07135 (WOC73_07135)	-	1424084..1424470 (-)	387	WP_001110179.1	hypothetical protein	-
WOC73_RS07140 (WOC73_07140)	map	1424687..1425445 (-)	759	WP_000636144.1	type I methionyl aminopeptidase	-
WOC73_RS07145 (WOC73_07145)	-	1425976..1426962 (+)	987	WP_031811349.1	aromatic acid exporter family protein	-
WOC73_RS07150 (WOC73_07150)	-	1427452..1427865 (-)	414	WP_001549145.1	hypothetical protein	-
WOC73_RS07155 (WOC73_07155)	-	1427894..1428004 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=971447 WOC73_RS07125 WP_001017131.1 1422328..1423371(-) (vraS) [Staphylococcus aureus strain TUM22730]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=971447 WOC73_RS07125 WP_001017131.1 1422328..1423371(-) (vraS) [Staphylococcus aureus strain TUM22730]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1