Detailed information NTG0971384

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: WOC46_RS05620
• Genome accession: NZ_CP150733
• Coordinates: 1151489..1152532 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM22741
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1146489..1157532

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC46_RS05590 (WOC46_05590)	-	1146855..1146966 (+)	112	Protein_1101	hypothetical protein	-
WOC46_RS05595 (WOC46_05595)	-	1146995..1147408 (+)	414	WP_001837236.1	hypothetical protein	-
WOC46_RS05600 (WOC46_05600)	-	1147898..1148884 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
WOC46_RS05605 (WOC46_05605)	map	1149415..1150173 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
WOC46_RS05610 (WOC46_05610)	-	1150390..1150776 (+)	387	WP_001110179.1	hypothetical protein	-
WOC46_RS05615 (WOC46_05615)	liaF	1150791..1151492 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
WOC46_RS05620 (WOC46_05620)	vraS	1151489..1152532 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
WOC46_RS05625 (WOC46_05625)	vraR	1152522..1153151 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
WOC46_RS05630 (WOC46_05630)	-	1153263..1154474 (-)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
WOC46_RS05635 (WOC46_05635)	-	1154752..1155027 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
WOC46_RS05640 (WOC46_05640)	-	1155034..1155498 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
WOC46_RS05645 (WOC46_05645)	-	1155645..1155845 (+)	201	WP_000180460.1	DUF1128 family protein	-
WOC46_RS05650 (WOC46_05650)	-	1155848..1157104 (+)	1257	WP_001793428.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=971384 WOC46_RS05620 WP_001017131.1 1151489..1152532(+) (vraS) [Staphylococcus aureus strain TUM22741]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=971384 WOC46_RS05620 WP_001017131.1 1151489..1152532(+) (vraS) [Staphylococcus aureus strain TUM22741]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1