Detailed information NTG0971379

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC46_RS02145
• Genome accession: NZ_CP150733
• Coordinates: 465679..466566 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain TUM22741
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 460679..471566

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC46_RS02115 (WOC46_02115)	-	461411..462172 (+)	762	Protein_420	alpha/beta hydrolase family protein	-
WOC46_RS02120 (WOC46_02120)	-	462417..462872 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC46_RS02125 (WOC46_02125)	-	462994..463095 (+)	102	WP_000731972.1	SE2200 family small protein	-
WOC46_RS02130 (WOC46_02130)	-	463155..464579 (-)	1425	WP_000953748.1	alkaline phosphatase	-
WOC46_RS02135 (WOC46_02135)	-	464777..464977 (+)	201	WP_000604727.1	hypothetical protein	-
WOC46_RS02140 (WOC46_02140)	braR	465003..465668 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC46_RS02145 (WOC46_02145)	braS	465679..466566 (+)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC46_RS02150 (WOC46_02150)	-	466674..467429 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC46_RS02155 (WOC46_02155)	-	467426..469426 (+)	2001	WP_000776740.1	ABC transporter permease	-
WOC46_RS02160 (WOC46_02160)	-	470085..470198 (+)	114	Protein_429	hypothetical protein	-
WOC46_RS02165 (WOC46_02165)	-	470580..470840 (+)	261	WP_001791974.1	hypothetical protein	-
WOC46_RS02170 (WOC46_02170)	-	470850..471347 (+)	498	WP_001065268.1	glutathione peroxidase	-
WOC46_RS02175 (WOC46_02175)	-	471455..471547 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=971379 WOC46_RS02145 WP_000143417.1 465679..466566(+) (braS) [Staphylococcus aureus strain TUM22741]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=971379 WOC46_RS02145 WP_000143417.1 465679..466566(+) (braS) [Staphylococcus aureus strain TUM22741]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99