Detailed information NTG0971342

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC72_RS05180
• Genome accession: NZ_CP150731
• Coordinates: 992158..993045 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain TUM22744
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 987158..998045

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC72_RS05150 (WOC72_05150)	-	987177..987269 (+)	93	WP_010956583.1	hypothetical protein	-
WOC72_RS05155 (WOC72_05155)	-	987377..987874 (-)	498	WP_001065268.1	glutathione peroxidase	-
WOC72_RS05160 (WOC72_05160)	-	987884..988144 (-)	261	WP_001791974.1	hypothetical protein	-
WOC72_RS05165 (WOC72_05165)	-	988526..988639 (-)	114	Protein_979	hypothetical protein	-
WOC72_RS05170 (WOC72_05170)	-	989298..991298 (-)	2001	WP_000776740.1	ABC transporter permease	-
WOC72_RS05175 (WOC72_05175)	-	991295..992050 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC72_RS05180 (WOC72_05180)	braS	992158..993045 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC72_RS05185 (WOC72_05185)	braR	993056..993721 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC72_RS05190 (WOC72_05190)	-	993747..993947 (-)	201	WP_000604727.1	hypothetical protein	-
WOC72_RS05195 (WOC72_05195)	-	994145..995569 (+)	1425	WP_000953748.1	alkaline phosphatase	-
WOC72_RS05200 (WOC72_05200)	-	995639..995749 (+)	111	WP_001791296.1	hypothetical protein	-
WOC72_RS05205 (WOC72_05205)	-	995852..996307 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC72_RS05210 (WOC72_05210)	-	996552..997313 (-)	762	Protein_988	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=971342 WOC72_RS05180 WP_000143417.1 992158..993045(-) (braS) [Staphylococcus aureus strain TUM22744]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=971342 WOC72_RS05180 WP_000143417.1 992158..993045(-) (braS) [Staphylococcus aureus strain TUM22744]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99