Detailed information NTG0971329

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC58_RS11670
• Genome accession: NZ_CP150729
• Coordinates: 2343948..2344835 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain TUM22749
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2338948..2349835

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC58_RS11640 (WOC58_11640)	-	2339680..2340441 (+)	762	Protein_2257	alpha/beta hydrolase family protein	-
WOC58_RS11645 (WOC58_11645)	-	2340686..2341141 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC58_RS11650 (WOC58_11650)	-	2341263..2341364 (+)	102	WP_000731972.1	SE2200 family small protein	-
WOC58_RS11655 (WOC58_11655)	-	2341424..2342848 (-)	1425	WP_000953748.1	alkaline phosphatase	-
WOC58_RS11660 (WOC58_11660)	-	2343046..2343246 (+)	201	WP_000604727.1	hypothetical protein	-
WOC58_RS11665 (WOC58_11665)	braR	2343272..2343937 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC58_RS11670 (WOC58_11670)	braS	2343948..2344835 (+)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC58_RS11675 (WOC58_11675)	-	2344943..2345698 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC58_RS11680 (WOC58_11680)	-	2345695..2347695 (+)	2001	WP_000776740.1	ABC transporter permease	-
WOC58_RS11685 (WOC58_11685)	-	2348354..2348467 (+)	114	Protein_2266	hypothetical protein	-
WOC58_RS11690 (WOC58_11690)	-	2348849..2349109 (+)	261	WP_001791974.1	hypothetical protein	-
WOC58_RS11695 (WOC58_11695)	-	2349119..2349616 (+)	498	WP_001065268.1	glutathione peroxidase	-
WOC58_RS11700 (WOC58_11700)	-	2349724..2349816 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=971329 WOC58_RS11670 WP_000143417.1 2343948..2344835(+) (braS) [Staphylococcus aureus strain TUM22749]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=971329 WOC58_RS11670 WP_000143417.1 2343948..2344835(+) (braS) [Staphylococcus aureus strain TUM22749]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99