Detailed information NTG0971280

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: WOC55_RS11900
• Genome accession: NZ_CP150727
• Coordinates: 2354614..2355501 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain TUM22750
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2349614..2360501

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC55_RS11870 (WOC55_11870)	-	2349633..2349725 (+)	93	WP_010956583.1	hypothetical protein	-
WOC55_RS11875 (WOC55_11875)	-	2349833..2350330 (-)	498	WP_001065268.1	glutathione peroxidase	-
WOC55_RS11880 (WOC55_11880)	-	2350340..2350600 (-)	261	WP_001791974.1	hypothetical protein	-
WOC55_RS11885 (WOC55_11885)	-	2350982..2351095 (-)	114	Protein_2296	hypothetical protein	-
WOC55_RS11890 (WOC55_11890)	-	2351754..2353754 (-)	2001	WP_000776740.1	ABC transporter permease	-
WOC55_RS11895 (WOC55_11895)	-	2353751..2354506 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
WOC55_RS11900 (WOC55_11900)	braS	2354614..2355501 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
WOC55_RS11905 (WOC55_11905)	braR	2355512..2356177 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
WOC55_RS11910 (WOC55_11910)	-	2356203..2356403 (-)	201	WP_000604727.1	hypothetical protein	-
WOC55_RS11915 (WOC55_11915)	-	2356601..2358025 (+)	1425	WP_000953748.1	alkaline phosphatase	-
WOC55_RS11920 (WOC55_11920)	-	2358095..2358205 (+)	111	WP_001791296.1	hypothetical protein	-
WOC55_RS11925 (WOC55_11925)	-	2358308..2358763 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
WOC55_RS11930 (WOC55_11930)	-	2359008..2359769 (-)	762	Protein_2305	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=971280 WOC55_RS11900 WP_000143417.1 2354614..2355501(-) (braS) [Staphylococcus aureus strain TUM22750]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=971280 WOC55_RS11900 WP_000143417.1 2354614..2355501(-) (braS) [Staphylococcus aureus strain TUM22750]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99