Detailed information NTG0971274

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: WOC55_RS08120
• Genome accession: NZ_CP150727
• Coordinates: 1627345..1628388 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM22750
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1622345..1633388

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC55_RS08090 (WOC55_08090)	-	1622773..1624029 (-)	1257	WP_001793428.1	aminopeptidase	-
WOC55_RS08095 (WOC55_08095)	-	1624032..1624232 (-)	201	WP_000180460.1	DUF1128 family protein	-
WOC55_RS08100 (WOC55_08100)	-	1624379..1624843 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
WOC55_RS08105 (WOC55_08105)	-	1624850..1625125 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
WOC55_RS08110 (WOC55_08110)	-	1625403..1626614 (+)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
WOC55_RS08115 (WOC55_08115)	vraR	1626726..1627355 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
WOC55_RS08120 (WOC55_08120)	vraS	1627345..1628388 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
WOC55_RS08125 (WOC55_08125)	liaF	1628385..1629086 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
WOC55_RS08130 (WOC55_08130)	-	1629101..1629487 (-)	387	WP_001110179.1	hypothetical protein	-
WOC55_RS08135 (WOC55_08135)	map	1629704..1630462 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
WOC55_RS08140 (WOC55_08140)	-	1630993..1631979 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
WOC55_RS08145 (WOC55_08145)	-	1632528..1632941 (-)	414	WP_001837236.1	hypothetical protein	-
WOC55_RS08150 (WOC55_08150)	-	1632970..1633080 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=971274 WOC55_RS08120 WP_001017131.1 1627345..1628388(-) (vraS) [Staphylococcus aureus strain TUM22750]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=971274 WOC55_RS08120 WP_001017131.1 1627345..1628388(-) (vraS) [Staphylococcus aureus strain TUM22750]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1