Detailed information NTG0971031

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXR45_RS14295
• Genome accession: NZ_CP150657
• Coordinates: 2815469..2816356 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain BSN214
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2810469..2821356

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR45_RS14265 (UXR45_14265)	-	2810488..2810580 (+)	93	WP_010956583.1	hypothetical protein	-
UXR45_RS14270 (UXR45_14270)	-	2810688..2811185 (-)	498	WP_001065268.1	glutathione peroxidase	-
UXR45_RS14275 (UXR45_14275)	-	2811195..2811455 (-)	261	WP_001789910.1	hypothetical protein	-
UXR45_RS14280 (UXR45_14280)	-	2811837..2811950 (-)	114	WP_001791776.1	hypothetical protein	-
UXR45_RS14285 (UXR45_14285)	-	2812609..2814609 (-)	2001	WP_000776751.1	ABC transporter permease	-
UXR45_RS14290 (UXR45_14290)	-	2814606..2815361 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXR45_RS14295 (UXR45_14295)	braS	2815469..2816356 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXR45_RS14300 (UXR45_14300)	braR	2816367..2817032 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXR45_RS14305 (UXR45_14305)	-	2817058..2817258 (-)	201	WP_000604728.1	hypothetical protein	-
UXR45_RS14310 (UXR45_14310)	-	2817456..2818880 (+)	1425	WP_000953744.1	alkaline phosphatase	-
UXR45_RS14315 (UXR45_14315)	-	2818950..2819060 (+)	111	WP_001791296.1	hypothetical protein	-
UXR45_RS14320 (UXR45_14320)	-	2819163..2819618 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXR45_RS14325 (UXR45_14325)	-	2819863..2820624 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=971031 UXR45_RS14295 WP_000143419.1 2815469..2816356(-) (braS) [Staphylococcus aureus strain BSN214]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=971031 UXR45_RS14295 WP_000143419.1 2815469..2816356(-) (braS) [Staphylococcus aureus strain BSN214]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997