Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   ACLFAM_RS05695 Genome accession   NZ_CP178226
Coordinates   1137760..1139730 (-) Length   656 a.a.
NCBI ID   WP_039116757.1    Uniprot ID   -
Organism   Lactococcus lactis strain L-WY410     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1132760..1144730
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLFAM_RS05665 (ACLFAM_05665) - 1133213..1133413 (+) 201 WP_003131983.1 hypothetical protein -
  ACLFAM_RS05670 (ACLFAM_05670) glnA 1133472..1134812 (-) 1341 WP_003131984.1 type I glutamate--ammonia ligase -
  ACLFAM_RS05675 (ACLFAM_05675) - 1134874..1135239 (-) 366 WP_003131985.1 MerR family transcriptional regulator -
  ACLFAM_RS05680 (ACLFAM_05680) - 1135340..1135777 (-) 438 WP_039116513.1 low molecular weight protein-tyrosine-phosphatase -
  ACLFAM_RS05685 (ACLFAM_05685) ruvB 1135926..1136927 (-) 1002 WP_003131994.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  ACLFAM_RS05690 (ACLFAM_05690) ruvA 1137054..1137647 (-) 594 WP_017865241.1 Holliday junction branch migration protein RuvA Machinery gene
  ACLFAM_RS05695 (ACLFAM_05695) hexB 1137760..1139730 (-) 1971 WP_039116757.1 DNA mismatch repair endonuclease MutL Machinery gene
  ACLFAM_RS05700 (ACLFAM_05700) - 1139859..1140554 (-) 696 WP_023190211.1 hypothetical protein -
  ACLFAM_RS05705 (ACLFAM_05705) hexA 1140669..1143191 (-) 2523 WP_023190212.1 DNA mismatch repair protein MutS Machinery gene
  ACLFAM_RS05710 (ACLFAM_05710) - 1143385..1143732 (-) 348 WP_012898702.1 RicAFT regulatory complex protein RicA family protein -

Sequence

Protein


Download         Length: 656 a.a.        Molecular weight: 73616.84 Da        Isoelectric Point: 5.3130

>NTDB_id=971023 ACLFAM_RS05695 WP_039116757.1 1137760..1139730(-) (hexB) [Lactococcus lactis strain L-WY410]
MGKIIELNEALANQIAAGEVVERPASVVKELVENSIDAGSSKIIINVEEAGLRLIEVIDNGLGLEKEDVALALRRHATSK
IKDSADLFRIRTLGFRGEALPSIASVSQMTIETSTAGEESGTKLIAKGGNIETLEPLAKRVGTKISVANLFYNTPARLKY
IKSLQAELSHITDIINRLSLAHPEISFTLVNEGKEFLKTAGNGDLRQVIAAIYGIGTAKKMRQIKGSDLDFGLTGYVSIP
ELTRANRNYITILINGRFIKNFLLNRAILEGYGNRLMVGRFPFAILSIKIDPTLADVNVHPTKQEVRLSKERELMALISK
AIDEALSEGVLIPEALENLQGRAKEKESLSVQTELPLQNNPLYYDNVRQDFYVREEATFKINKNQASNDSSEQTFDNFTE
NQLNTDAVSEKMTDRTVESTTEITDNSLENTVSNFEIDFDNEVKISQSSTFPQLEYLAQLHATYLLCQSKEGLYLVDQHA
AQERIKYEYWKDKIGEVSMEQQILLAPYLFTLPKNDFIVLAEKKDLLHEAGVFLEEYGENQFILREHPIWLKETEIEKSI
NEMIDIILSSKEFSLKKYRHDLAAMVACKSSIKANHPLDAESARALLAELATCKNPYSCAHGRPTIVHFSGDDIQKMFRR
IQETHHSKAASWKDFE

Nucleotide


Download         Length: 1971 bp        

>NTDB_id=971023 ACLFAM_RS05695 WP_039116757.1 1137760..1139730(-) (hexB) [Lactococcus lactis strain L-WY410]
GTGGGAAAAATTATTGAACTAAATGAAGCGCTCGCCAATCAAATTGCTGCTGGAGAGGTGGTTGAGCGGCCTGCTAGTGT
TGTCAAAGAATTAGTCGAAAACTCAATTGATGCTGGAAGCAGTAAAATTATTATCAATGTTGAAGAAGCTGGTTTGCGAT
TAATTGAAGTCATTGATAATGGTTTGGGTTTGGAAAAAGAAGATGTGGCTTTGGCTTTGCGTCGTCATGCAACAAGTAAA
ATCAAGGATTCGGCAGATTTGTTTCGGATTAGAACACTCGGTTTTCGGGGGGAGGCTCTGCCATCAATCGCTTCTGTCAG
CCAGATGACCATTGAAACAAGTACGGCTGGGGAAGAATCAGGAACAAAACTAATTGCTAAAGGTGGAAATATCGAAACTT
TAGAACCACTTGCTAAGCGCGTGGGGACGAAAATTTCTGTTGCTAATCTTTTTTATAATACACCAGCAAGACTCAAGTAT
ATCAAGTCCTTGCAGGCTGAACTTTCTCATATCACAGACATCATCAACCGATTGAGTCTGGCTCATCCAGAGATTTCCTT
TACTTTAGTTAATGAGGGTAAAGAATTTTTGAAAACGGCTGGAAATGGTGATTTACGTCAGGTTATTGCTGCAATTTATG
GCATAGGGACAGCGAAAAAAATGCGTCAAATCAAGGGTTCAGACTTAGATTTTGGACTAACAGGTTATGTCAGCATACCA
GAGCTGACAAGGGCTAATCGTAATTATATTACGATTTTAATAAATGGTCGATTTATCAAAAACTTTTTATTGAATCGGGC
AATTTTAGAAGGATATGGCAATCGATTGATGGTGGGACGGTTCCCTTTTGCTATTTTATCGATTAAAATTGACCCAACAC
TTGCTGATGTTAATGTTCATCCGACAAAACAAGAGGTGCGTTTGTCTAAAGAGCGTGAATTGATGGCTTTAATTTCTAAA
GCAATTGATGAGGCTTTATCAGAAGGTGTTTTGATTCCAGAAGCTTTGGAAAATTTGCAAGGAAGAGCTAAAGAAAAGGA
GAGTCTTTCTGTTCAAACGGAACTTCCTTTGCAAAATAATCCTTTATATTATGATAATGTTCGCCAAGATTTTTATGTCA
GAGAAGAGGCAACTTTTAAAATCAATAAAAATCAAGCTTCAAATGATTCGTCTGAACAAACTTTTGATAATTTTACAGAA
AATCAACTTAATACAGATGCTGTCAGTGAAAAAATGACTGACAGAACTGTGGAAAGTACTACTGAAATTACTGACAACAG
TCTAGAAAATACTGTCAGCAACTTTGAAATTGATTTTGATAATGAAGTAAAGATAAGTCAGTCATCAACTTTTCCGCAGC
TTGAATACTTGGCACAATTGCATGCGACTTATTTACTTTGTCAGTCCAAAGAAGGACTTTACTTGGTTGACCAACATGCG
GCTCAAGAGCGAATCAAATATGAGTATTGGAAAGATAAAATTGGTGAGGTCAGTATGGAGCAACAAATTTTACTTGCACC
ATATTTGTTCACTTTACCCAAAAATGATTTTATTGTTTTAGCCGAGAAGAAAGATTTGTTGCATGAAGCCGGTGTTTTCT
TAGAAGAATACGGAGAAAATCAATTCATTTTAAGAGAACATCCAATCTGGTTAAAAGAAACCGAGATAGAGAAATCAATT
AATGAAATGATTGATATTATTCTCTCATCAAAAGAATTTTCACTCAAAAAATATCGTCATGATTTAGCTGCAATGGTTGC
TTGTAAAAGTTCAATTAAAGCTAATCATCCCCTTGATGCCGAGTCAGCTAGAGCATTGCTTGCAGAATTAGCAACTTGTA
AAAATCCTTATAGTTGTGCGCATGGACGGCCAACGATTGTTCATTTTTCAGGGGATGACATTCAAAAAATGTTCCGGAGA
ATCCAAGAAACGCATCATTCAAAAGCAGCTTCGTGGAAAGATTTTGAGTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(455-598)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

56.989

99.238

0.566

Multiple sequence alignment