Detailed information NTG0971019

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: UXR45_RS10480
• Genome accession: NZ_CP150657
• Coordinates: 2028952..2031153 (+)
• Length: 733 a.a.
• NCBI ID: WP_001548978.1
• Uniprot ID: A0AB73FPE0
• Organism: Staphylococcus aureus strain BSN214
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2023952..2036153

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR45_RS10440 (UXR45_10440)	aroE	2024349..2025155 (+)	807	WP_000666761.1	shikimate dehydrogenase	-
UXR45_RS10445 (UXR45_10445)	yhbY	2025159..2025449 (+)	291	WP_000955231.1	ribosome assembly RNA-binding protein YhbY	-
UXR45_RS10450 (UXR45_10450)	nadD	2025452..2026021 (+)	570	WP_000725162.1	nicotinate (nicotinamide) nucleotide adenylyltransferase	-
UXR45_RS10455 (UXR45_10455)	yqeK	2026011..2026595 (+)	585	WP_001019324.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
UXR45_RS10460 (UXR45_10460)	rsfS	2026596..2026949 (+)	354	WP_001088022.1	ribosome silencing factor	-
UXR45_RS10465 (UXR45_10465)	-	2026952..2027668 (+)	717	WP_000084829.1	class I SAM-dependent methyltransferase	-
UXR45_RS10470 (UXR45_10470)	comEA	2027708..2028394 (+)	687	WP_001792568.1	ComEA family DNA-binding protein	Machinery gene
UXR45_RS10475 (UXR45_10475)	-	2028486..2028947 (+)	462	WP_000439693.1	ComE operon protein 2	-
UXR45_RS10480 (UXR45_10480)	comEC	2028952..2031153 (+)	2202	WP_001548978.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
UXR45_RS10485 (UXR45_10485)	holA	2031210..2032184 (+)	975	WP_001282562.1	DNA polymerase III subunit delta	-
UXR45_RS10490 (UXR45_10490)	rpsT	2032229..2032480 (-)	252	WP_001274017.1	30S ribosomal protein S20	-
UXR45_RS10495 (UXR45_10495)	lepA	2032826..2034649 (+)	1824	WP_000368341.1	translation elongation factor 4	-

Sequence

Protein

• Length: 733 a.a.
• Molecular weight: 84881.97 Da
• Isoelectric Point: 10.0277

>NTDB_id=971019 UXR45_RS10480 WP_001548978.1 2028952..2031153(+) (comEC) [Staphylococcus aureus strain BSN214]
MLFVALSMIVGVLWNSSKVLSTFLFILLLYITYRKNKIVYAPISLFLIIFSAWYLHYSQQAIFNYINYIERNSQFNERAQ
VIQIQRQGSDTYKGRLSLKNEIYPFFLTDKKNFDLKKIESRNCIVKGQFKVNDNKFVTLKLQSIVVQSCLESNRSNLIEK
HKQFIMNRIYDSGIKFPDRIMALITGDVKEVNEQFKERVKEIVIYHLLAVSGSHIAAIVFLIYQPLKRLNLPLFVIKGIT
IIVLALFAQYTNYAPSAVRAIIMTTLVLVITKQIKIKSIQLLAFAFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQ
QLSKLQSLFIITFIAQLASFIVAIPSFHQLQWVGFLSNLIFVPYYSIILFPLSILFFITSHFIVGLTPLNYLVDLSFNFH
DWLLDLFTRIKQSHFSVPKFNDWIFIVFIISVYYIFWLLAKRKYILVTFWTIIILTLLITFPTNSHHKITMLNVGQGDSI
LYEGGKNQNVLIDTGGKVIDDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGEVEYIISHIKIKHIVIYNKG
YSSNTLMLLSKLSHKYNIKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNESLLL
KKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNL
KVDSSSYGNASGL

Nucleotide

• Length: 2202 bp

>NTDB_id=971019 UXR45_RS10480 WP_001548978.1 2028952..2031153(+) (comEC) [Staphylococcus aureus strain BSN214]
TTGCTGTTTGTCGCGTTATCAATGATTGTAGGAGTGCTTTGGAATTCTAGCAAAGTGCTCTCTACATTTCTTTTCATTTT
ACTTTTGTATATTACTTATCGTAAAAATAAAATCGTTTATGCCCCTATTTCTCTCTTTTTAATCATTTTCTCCGCATGGT
ATTTACATTATTCACAACAAGCAATATTTAATTATATCAATTATATTGAACGTAATTCTCAGTTTAATGAGCGTGCTCAA
GTAATCCAAATTCAACGTCAAGGTAGTGACACATATAAAGGTAGGTTGAGTTTAAAAAATGAAATATATCCTTTCTTTTT
AACAGATAAAAAGAATTTTGATTTAAAGAAAATTGAAAGTCGTAATTGTATTGTTAAAGGACAATTCAAAGTTAATGACA
ATAAGTTTGTAACTCTTAAATTACAAAGTATAGTTGTACAAAGCTGCCTAGAATCGAACCGGTCTAATTTAATTGAGAAA
CATAAACAGTTTATAATGAATCGAATTTATGATTCGGGTATTAAGTTTCCGGATCGTATTATGGCATTGATTACTGGTGA
CGTAAAAGAAGTTAATGAGCAATTTAAGGAACGTGTTAAAGAGATAGTTATATATCATTTGCTGGCAGTTAGTGGCTCGC
ATATAGCTGCAATTGTATTTTTAATTTACCAACCTTTAAAACGATTAAATTTACCTTTATTTGTCATTAAAGGAATTACA
ATCATTGTATTAGCTTTATTTGCTCAATACACAAATTATGCACCTAGTGCTGTAAGAGCTATAATAATGACAACTCTTGT
ACTGGTTATTACTAAGCAAATTAAAATAAAGAGTATTCAGCTATTAGCATTTGCATTTATAATTATGTTTATTTTAAATC
CACTAGTTGTTTATGATATTGGATTTCAATTTTCATTCATCATTTCATTTTTTATTATGCTACTTTTTCCTTTTTTACAG
CAATTGTCAAAGTTACAATCATTATTCATAATTACGTTTATTGCACAATTAGCTTCATTTATCGTTGCCATTCCAAGCTT
TCATCAACTTCAATGGGTGGGATTTTTATCTAATTTGATTTTTGTACCGTACTATTCGATTATATTGTTTCCGCTATCTA
TTTTATTCTTTATTACAAGTCATTTTATTGTGGGATTAACGCCGCTAAATTACTTGGTTGACCTAAGTTTTAATTTTCAT
GACTGGTTACTAGACCTATTCACAAGAATCAAGCAATCACATTTTTCTGTTCCCAAGTTTAATGATTGGATATTTATAGT
ATTTATAATTTCTGTTTATTACATATTTTGGTTATTGGCTAAACGTAAATATATATTGGTTACGTTTTGGACTATAATTA
TTCTGACATTATTAATAACGTTTCCAACAAATTCACATCACAAAATTACAATGTTAAATGTGGGGCAGGGAGACAGTATT
TTATATGAAGGCGGTAAGAACCAAAATGTCTTGATTGATACAGGTGGGAAAGTGATTGATGATACTAAACAACCTAGTTA
TTCAATTTCTAAATATCATATTTTACCAACGCTAAATGAAAGAGGGATAAATGAATTAGAGTATCTAATTTTAACACATC
CACACAATGACCATATTGGTGAAGTGGAATATATTATTAGTCATATTAAAATTAAACATATAGTGATATACAATAAGGGA
TATAGTAGTAATACATTGATGTTATTATCGAAATTAAGCCATAAGTACAACATTAAACTTATGGATGTAAGACAAGTTAG
TAGTTTTAAACTTGGAGATAGTAGTTTTCTATTTTTTGATAGTTTTATTCCAAATAGCCGAGATAAAAATGAGTATTCGA
TTATTACTATGATTACATATCAAAATAAAAAAGTTTTATTAATGGGCGATGCTAGTAAAAATAATGAATCTTTACTACTA
AAAAAATATAACTTGCCGGAGATTGATATTTTAAAAGTAGGACATCATGGGAGCAAGACAAGTAGTTCTAAAGAATTTAT
AGAGATGATTAAGCCTAAAATAAGTTTGATTTCTTCTGGGAAGAACAATATGTATCATCTTCCTAATATAGAAGTTGTTA
AACGATTGCAAAGGATTCGCAGTCGCATTTACAATAGTCAACAAAACGGTCAAGTTACAATTGACTTAGATGATAATTTA
AAAGTTGATTCAAGCTCTTATGGAAATGCAAGTGGTTTATAG

Domains

Predicted by InterproScan.

• Competence protein (Competence) (183-441)

• Metallo-beta-lactamase superfamily (Lactamase_B) (474-679)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Staphylococcus aureus N315	98.363	100	0.984
comEC	Staphylococcus aureus MW2	97.954	100	0.98