Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   ACLFAM_RS02490 Genome accession   NZ_CP178226
Coordinates   517195..519525 (-) Length   776 a.a.
NCBI ID   WP_017864836.1    Uniprot ID   -
Organism   Lactococcus lactis strain L-WY410     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 512195..524525
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLFAM_RS02460 (ACLFAM_02460) - 512785..513768 (-) 984 WP_039115737.1 LacI family DNA-binding transcriptional regulator -
  ACLFAM_RS02465 (ACLFAM_02465) purB 513902..515197 (-) 1296 WP_029344200.1 adenylosuccinate lyase -
  ACLFAM_RS02470 (ACLFAM_02470) aroD 515394..516074 (-) 681 WP_003129440.1 type I 3-dehydroquinate dehydratase -
  ACLFAM_RS02480 (ACLFAM_02480) - 516337..516540 (-) 204 WP_010906074.1 DUF2969 domain-containing protein -
  ACLFAM_RS02485 (ACLFAM_02485) trxA 516784..517098 (-) 315 WP_003129442.1 thioredoxin -
  ACLFAM_RS02490 (ACLFAM_02490) mutS/mutS2 517195..519525 (-) 2331 WP_017864836.1 endonuclease MutS2 Machinery gene
  ACLFAM_RS02495 (ACLFAM_02495) - 519570..520130 (-) 561 WP_003129445.1 CvpA family protein -
  ACLFAM_RS02500 (ACLFAM_02500) - 520290..521255 (-) 966 WP_023189681.1 NAD(P)/FAD-dependent oxidoreductase -
  ACLFAM_RS02505 (ACLFAM_02505) ccpA 521394..522392 (-) 999 WP_039115741.1 catabolite control protein A Regulator
  ACLFAM_RS02510 (ACLFAM_02510) - 522607..523695 (+) 1089 WP_003129448.1 M24 family metallopeptidase -

Sequence

Protein


Download         Length: 776 a.a.        Molecular weight: 87266.19 Da        Isoelectric Point: 6.9607

>NTDB_id=970981 ACLFAM_RS02490 WP_017864836.1 517195..519525(-) (mutS/mutS2) [Lactococcus lactis strain L-WY410]
MNKKILQILEYDKVKEQFMNALTTAQGQQELKDLKPLTDKEKIQLLFDEVADFRLLTQENGLLNLGKTNDLTEILRRLEL
EASLSGKEFVEIKKVIQLGINIQRFFDEAENVETPSLAITLEKLVDLSALVKKLEIFDNAGSLYDNASLELMHIRASIKS
HQSEIRKIMQEMLTKNLSSLSENVITIRNDRQVLPVKAENKNKIAGVVHDMSASGQTLYIEPNAVVSLNNKLNQKRIEER
QEITRIYRELASQLKPYSFDIRQNAWLIGHIDFVRAKYLYLAANKATLPELTTDKDITLFAARHPLIEAKIVVANDIKFD
AGLNTIVITGPNTGGKTITLKTVGLLTILAQSGLPILAADGSRIHLFDDIFADIGDEQSIEQSLSTFSSHMTNIVHILAQ
ADENSLVLFDELGAGTDPKEGAALAIAILENLRERNVKTMASTHYPELKAYGVETQRVINASMEFNIDKMQPTYHLQLGV
PGRSNALEISRRLGLPETIISVASQQISDSEHDVNQMIEKLEEKTREVIESSRNIKKIERENQSLHKDLTKVYNQINRER
EFELEKAQKEAQEVVKKASLEAQEILKNLNDKAALKPHEIIAARKELEGLAPTIDFSKNKVLKKAKAQRGLKQGAEVNVT
SYGQRGKLIRLEKDGRWTVQMGSITTRLNEDEFEVIESPEQIQAKTKNVSKKVTSKVKAQLDLRGMRYEEAELELDNYID
QALLANLIQITIVHGIGTGVIREMVQKKLQKHRHIKSYEYAPINAGGSGATIAILK

Nucleotide


Download         Length: 2331 bp        

>NTDB_id=970981 ACLFAM_RS02490 WP_017864836.1 517195..519525(-) (mutS/mutS2) [Lactococcus lactis strain L-WY410]
ATGAATAAAAAAATTCTCCAAATATTGGAATATGATAAAGTCAAAGAACAGTTCATGAATGCTTTGACGACAGCGCAGGG
TCAACAAGAATTAAAAGATTTAAAACCTTTGACAGATAAGGAAAAAATTCAGCTCCTTTTTGATGAAGTTGCTGATTTTC
GCTTATTGACCCAAGAAAATGGCCTATTAAATTTAGGAAAAACAAATGATTTAACAGAAATACTCAGACGTCTAGAGCTT
GAAGCCAGTCTTTCAGGCAAGGAATTCGTTGAAATAAAAAAAGTGATTCAATTAGGGATTAATATTCAACGCTTTTTTGA
TGAAGCTGAAAATGTTGAAACACCTTCACTAGCTATTACTTTGGAAAAATTGGTTGATTTATCAGCATTAGTCAAAAAAT
TAGAAATTTTTGATAATGCGGGAAGTCTTTATGATAATGCCAGTCTCGAATTGATGCATATCCGTGCTTCAATCAAGAGT
CATCAATCAGAAATTCGGAAAATCATGCAGGAAATGCTGACCAAAAATCTCTCATCTTTGAGTGAAAATGTCATCACTAT
CCGAAATGACCGACAAGTGCTTCCTGTAAAAGCAGAAAACAAAAATAAAATTGCTGGTGTAGTTCATGATATGTCTGCTT
CAGGTCAAACGCTTTATATTGAACCAAATGCGGTTGTTTCATTAAATAATAAACTTAATCAAAAGAGAATTGAAGAACGC
CAAGAAATCACAAGAATTTATCGTGAGCTTGCTAGTCAATTAAAACCTTATAGCTTTGATATAAGACAAAATGCTTGGCT
GATTGGTCATATTGATTTTGTTCGTGCCAAGTATCTTTATTTAGCAGCGAATAAAGCGACACTTCCAGAATTAACAACCG
ATAAAGATATTACCCTTTTTGCAGCTCGCCATCCTTTGATTGAAGCAAAAATAGTTGTGGCAAATGATATTAAATTTGAT
GCAGGGCTCAATACGATTGTTATTACCGGTCCAAATACGGGTGGGAAGACCATTACTTTGAAAACAGTTGGTTTGTTGAC
AATATTGGCTCAATCAGGTCTGCCAATTTTAGCCGCTGATGGCAGTCGAATTCATCTTTTTGATGATATTTTTGCCGATA
TCGGTGATGAGCAATCCATTGAGCAAAGTTTATCAACTTTCTCAAGTCATATGACTAATATTGTTCATATTTTAGCTCAA
GCAGATGAAAATAGTTTGGTCTTGTTTGATGAACTTGGGGCAGGAACTGATCCAAAAGAAGGAGCGGCTCTTGCTATTGC
CATACTGGAAAATTTACGTGAACGAAATGTGAAAACCATGGCAAGTACTCATTATCCTGAGTTAAAAGCTTATGGGGTCG
AAACGCAACGAGTAATCAATGCAAGTATGGAATTTAACATTGATAAAATGCAACCCACTTATCATTTGCAACTGGGAGTG
CCTGGGCGTTCAAATGCCCTGGAAATTTCGAGAAGATTAGGTTTGCCAGAAACTATTATTTCAGTAGCCAGTCAACAAAT
TTCTGACAGTGAGCATGATGTCAATCAGATGATTGAAAAGTTGGAAGAAAAAACACGTGAAGTGATTGAAAGTTCAAGAA
ATATTAAAAAAATTGAACGAGAAAATCAAAGTTTACATAAAGATTTGACGAAAGTCTATAATCAAATTAATCGTGAGCGC
GAGTTTGAATTAGAAAAAGCACAAAAAGAAGCTCAAGAAGTAGTTAAAAAAGCGAGTCTTGAAGCGCAAGAAATTTTGAA
GAATCTCAATGATAAAGCAGCGTTGAAACCACATGAAATTATTGCTGCTAGAAAAGAACTTGAAGGTTTGGCTCCAACCA
TTGATTTTTCTAAAAATAAGGTTTTGAAAAAAGCGAAAGCACAAAGAGGACTTAAGCAAGGGGCTGAAGTTAATGTCACT
TCTTATGGTCAGCGTGGTAAATTGATTCGTTTAGAAAAAGATGGACGTTGGACGGTTCAAATGGGTTCAATCACGACTCG
TTTAAATGAAGATGAATTTGAAGTGATTGAAAGTCCAGAACAAATTCAAGCCAAAACTAAAAATGTCAGCAAGAAGGTGA
CTTCTAAAGTCAAAGCTCAACTTGATTTACGCGGGATGCGTTATGAAGAAGCAGAACTGGAATTGGATAATTATATTGAC
CAAGCTCTACTTGCAAATTTGATTCAAATTACGATTGTTCATGGGATTGGAACGGGTGTTATTCGAGAAATGGTACAGAA
AAAACTTCAAAAACACCGTCATATTAAATCTTATGAATATGCACCAATTAATGCTGGTGGCTCTGGAGCAACGATTGCTA
TTTTGAAGTAA

Domains

Predicted by InterProScan.

MutS2 and Smr-associated SH3 domain (MSSS)

(634-672)

Smr domain (Smr)

(701-776)

MutS domain V (MutS_V)

(326-508)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

42.748

100

0.433