Detailed information NTG0969784

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: ACJWMD_RS00305
• Genome accession: NZ_CP177182
• Coordinates: 50053..52584 (+)
• Length: 843 a.a.
• NCBI ID: WP_374937058.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain MRD6060
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 45053..57584

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJWMD_RS00285	purB	45295..46593 (+)	1299	WP_002886310.1	adenylosuccinate lyase	-
ACJWMD_RS00290	argS	47400..49091 (-)	1692	WP_411888498.1	arginine--tRNA ligase	-
ACJWMD_RS00295	argR	49246..49674 (+)	429	WP_411888514.1	arginine repressor	-
ACJWMD_RS00300	-	49674..50033 (+)	360	WP_002886313.1	YlbF family regulator	-
ACJWMD_RS00305	hexA	50053..52584 (+)	2532	WP_374937058.1	DNA mismatch repair protein MutS	Machinery gene
ACJWMD_RS00310	-	52618..52764 (-)	147	WP_411897080.1	DUF3021 family protein	-
ACJWMD_RS00315	-	52913..53134 (+)	222	Protein_41	GTPase	-
ACJWMD_RS00320	-	53122..53493 (-)	372	Protein_42	DUF3021 domain-containing protein	-
ACJWMD_RS00325	-	53490..53927 (-)	438	WP_002886318.1	LytTR family DNA-binding domain-containing protein	-
ACJWMD_RS00330	-	54106..54411 (+)	306	WP_002886319.1	hypothetical protein	-
ACJWMD_RS00335	mutL	54461..55512 (+)	1052	Protein_45	DNA mismatch repair endonuclease MutL	-
ACJWMD_RS00340	-	55579..56328 (+)	750	Protein_46	DNA mismatch repair protein MutL	-
ACJWMD_RS00345	-	56459..56680 (+)	222	WP_002886321.1	hypothetical protein	-
ACJWMD_RS00350	ruvA	56838..57428 (+)	591	WP_002886323.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 843 a.a.
• Molecular weight: 94623.67 Da
• Isoelectric Point: 4.6344

>NTDB_id=969784 ACJWMD_RS00305 WP_374937058.1 50053..52584(+) (hexA) [Streptococcus salivarius strain MRD6060]
MQQYLDIKENYPDAFLLFRMGDFYELFYEDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQAYIDVLVEMGYKVAIA
EQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKAGSRFGLAYMDVSTGEFFATELDDFSSVCSEIQNLK
AREVVLGYDLPEADEQVLVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQKAQHYEIKDY
LQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQAAIMERQNIIQVFLDNFFERSDLTESL
KGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFNDEALSRLLQELDALPELESLIRSAIDPDAPATITEG
GIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKATLKNSERFG
TAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVTAETNHYVRPVFNDEHRIVIDQ
GRHAVVEKVMGVQEYIPNTITFDSQTNVQLITGPNMSGKSTYMRQLALSVVMAQMGSYVPADSIDLPVFDAIYTRIGAAD
DLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHELTALSNTLTH
LVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGETVTIQPQEKVSPQEKPATETHV
NEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2532 bp

>NTDB_id=969784 ACJWMD_RS00305 WP_374937058.1 50053..52584(+) (hexA) [Streptococcus salivarius strain MRD6060]
ATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTCTTTCGTATGGGTGATTTTTACGAATTATT
TTACGAGGATGCTGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACCAGTCGTAATAAGAATGCCGATAATCCCATTC
CTATGGCTGGTGTTCCTTACCATTCAGCTCAAGCCTATATTGATGTTTTGGTTGAGATGGGCTACAAGGTAGCCATTGCT
GAGCAGATGGAGGATCCTAAACAGGCTGTTGGCGTGGTTAAGCGTGAGGTGGTTCAGGTTATCACCCCAGGTACAGTGGT
TGACAGCTCTAAACCTGATAATGCCAATAATTTCTTGGTGGCCATTGACAAGGCTGGAAGTCGATTCGGCCTGGCCTATA
TGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGACGATTTCAGTTCAGTTTGTAGTGAAATTCAGAACCTTAAG
GCACGTGAAGTAGTGCTTGGTTATGATTTACCTGAAGCTGATGAACAAGTTTTGGTGAAGCAACTCAACCTTCTACTTTC
CAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACTAGCTTGACAGACTTGGAAAGCAGTGTAGCGGGTAAAC
TTCTCCAGTATGTGCACCGTACTCAGATGCGTGAGCTCAGCCATTTACAAAAGGCTCAGCACTATGAGATTAAGGATTAC
TTGCAGATGTCCTATGCGACCAAGTCGAGTTTGGATTTGTTGGAAAATGCGAGAACGGGCAAGAAACACGGTTCTCTTTT
CTGGCTCCTGGATGAAACCAAGACAGCTATGGGGATGCGTCTCTTACGTACTTGGATTGACCGTCCTTTAGTGAATCAGG
CTGCAATCATGGAGCGCCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTCGAGCGTAGTGACTTGACTGAGAGTCTT
AAAGGGGTTTATGATATTGAGCGCTTGGCTAGTCGTGTTTCCTTCGGAAAGGCTAACCCTAAAGATTTGATTCAACTAGG
TCATACTTTAGCTCAGGTTCCAGTTATTAAGGCAATTTTGGAGTCTTTTAATGATGAGGCCTTGTCACGTCTTTTACAAG
AATTGGATGCTCTGCCAGAATTAGAGAGTCTGATTCGGTCGGCTATCGATCCCGATGCTCCTGCAACCATTACAGAAGGT
GGTATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGATGAGTGAAGGAACGTCATGGATCGCAGA
CATCGAAGCCAAGGAACGTGAAGCGTCTGGTATTACAACACTAAAAATTGATTATAACCGTAAAGATGGTTATTACTTCC
ATGTGACCAACTCTAACCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCAACCCTGAAAAACTCGGAGCGCTTTGGA
ACTGCTGAGTTGGCTAAGATTGAAGGTGAAATGCTTGAGGCACGTGAAAAGTCATCAACGCTAGAGTATGATATTTTCAT
GCGTGTCCGTGAGCAGGTGGAACGCTATATTGACCGTTTGCAATCTTTGGCTAAGGCTATTGCGACAGTCGATGTACTTC
AGAGTTTGGCAGTTACAGCAGAGACTAATCATTATGTTCGTCCTGTGTTCAATGATGAACATCGTATCGTTATTGATCAA
GGTCGTCATGCAGTGGTTGAGAAGGTTATGGGTGTTCAGGAATACATTCCAAACACGATTACCTTTGACAGTCAGACCAA
TGTTCAGCTCATTACTGGGCCAAATATGAGTGGTAAATCTACTTATATGCGTCAGTTGGCCTTGTCAGTCGTTATGGCTC
AGATGGGCTCTTACGTACCAGCAGATAGTATTGATTTGCCAGTTTTTGACGCCATCTATACACGTATTGGTGCTGCAGAT
GACTTGATTTCAGGTCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAATCAGGCTATTAAGCGGGCGACACCTAATTC
CTTGATTATTTTTGATGAGTTGGGACGTGGGACAGCCACCTATGATGGTATGGCTTTGGCCCAGTCTATCATTGAGTTTA
TTCATGACAAGGTGGGGGCTAAAACCATGTTTGCTACCCATTATCATGAGTTGACAGCCCTGTCAAATACTTTGACACAC
CTTGTCAACGTTCATGTGGCGACACTTGAAAAGGACGGAGAGGTGACTTTCCTTCACAAGATTGTCGATGGCCCAGCTGA
CAAATCTTATGGTATTCATGTAGCTAAGATTGCAGGTTTACCAGCAGATTTACTGGAACGTGCTGACACCATCTTGACAC
AATTAGAGGGTGAGACAGTTACCATCCAACCTCAGGAAAAGGTATCGCCTCAAGAGAAGCCAGCCACTGAAACACATGTC
AACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCGGTTCTTCAAGAGTTACGTGATTTGGATATTTACAATAT
GACACCGATGCAGGTCATGATGGCTGTAGCAGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (1-109)

• MutS domain V (MutS_V) (590-776)

• MutS domain II (MutS_II) (117-230)

• MutS domain III (MutS_III) (247-537)

• MutS family domain IV (MutS_IV) (406-496)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	74.171	100	0.743
mutS	Pseudomonas stutzeri strain ATCC 17587	35.847	100	0.367