Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   ACJWMC_RS11165 Genome accession   NZ_CP177181
Coordinates   2352625..2354568 (-) Length   647 a.a.
NCBI ID   WP_002892430.1    Uniprot ID   J7SHM8
Organism   Streptococcus salivarius strain MRD1919     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2347625..2359568
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMC_RS11150 - 2348734..2350965 (-) 2232 WP_002892424.1 hypothetical protein -
  ACJWMC_RS11155 - 2350969..2352183 (-) 1215 WP_002892426.1 hypothetical protein -
  ACJWMC_RS11160 - 2352204..2352551 (-) 348 WP_002892428.1 hypothetical protein -
  ACJWMC_RS11165 clpE 2352625..2354568 (-) 1944 WP_002892430.1 AAA family ATPase Regulator
  ACJWMC_RS11170 - 2354569..2354970 (-) 402 WP_002892432.1 hypothetical protein -
  ACJWMC_RS11175 - 2354981..2355379 (-) 399 WP_002892434.1 hypothetical protein -
  ACJWMC_RS11180 - 2355415..2356512 (-) 1098 WP_224111190.1 hypothetical protein -
  ACJWMC_RS11185 - 2357173..2357964 (-) 792 WP_002892438.1 hypothetical protein -
  ACJWMC_RS11190 prx 2358081..2358269 (-) 189 WP_002892439.1 hypothetical protein Regulator
  ACJWMC_RS11195 - 2358376..2358534 (-) 159 WP_002892441.1 hypothetical protein -
  ACJWMC_RS11200 - 2358547..2359173 (-) 627 WP_037598719.1 hypothetical protein -
  ACJWMC_RS11205 - 2359194..2359547 (-) 354 WP_002892445.1 hypothetical protein -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 73675.65 Da        Isoelectric Point: 7.4132

>NTDB_id=969780 ACJWMC_RS11165 WP_002892430.1 2352625..2354568(-) (clpE) [Streptococcus salivarius strain MRD1919]
MKERTNHNLSKTPYIDKYTTDLTEKIRPKRQDFVAWGRQDEIRQVFISLNRLEKNSPVLIGEAGVGKTAIVEGICADILN
KKAHVPTCFQGKQVKQLELPAIQGKEFDHTGKEVNIIAKMDGLIKEFMAHKDEFILFIDEVHTIMGTGVEGSALDVANSL
KPALSRGEIYLISATTADEFMIIERDPAMERRLQPVYVDELDKEASILVLKKRRPKYKRELDIEIPNDAIKAAVELSIRY
ITDKMLPDKAIDIIDEASATANIDGKSEITLRDIASVIHRKKGIPMESLLRTSSTPVDFAEGMRAVVKGQDHVIRTIARL
MYKGIQGGQNKRRPLGTLLLLGTTGTGKTELAKQAAKQLFGSEEAMIRLDMSEYMTDNAVVRLIGNDERKGDLTEKIKKN
PYSLVLLDELEKAHPDVWALYLQMLDDGHLTDGRGRKINFKNTFIIATSNVGHKRIKDKYITSGQTFTEMNKTDYKEFMK
DMRDELIKIFKRPEFINRWKIEVTNILTKQTIDKIVYSKMAVHESSWFKEHHILINYEDVMDGDQTIDGKKYFYEYLSSV
GVSPEDGARPLERTIDEVLTDEIFEQLYFLGRKPQDYFMVDVSLSGHAPGTFAYGNSGRKTVQDRRQTHISVKRIPPEEY
GNYLLTS

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=969780 ACJWMC_RS11165 WP_002892430.1 2352625..2354568(-) (clpE) [Streptococcus salivarius strain MRD1919]
ATGAAGGAGAGGACTAACCATAATCTTAGTAAGACTCCTTATATTGACAAATACACAACAGACCTTACTGAGAAAATCAG
ACCCAAGCGTCAAGATTTTGTGGCTTGGGGTAGACAAGATGAAATCAGACAAGTCTTTATCTCACTGAATCGATTAGAAA
AAAACTCTCCTGTACTAATTGGTGAAGCTGGTGTAGGTAAAACAGCTATTGTAGAAGGAATTTGTGCAGATATTCTTAAC
AAGAAAGCCCACGTCCCAACATGTTTCCAAGGTAAGCAGGTTAAGCAACTAGAATTACCTGCTATCCAAGGGAAAGAATT
TGACCATACAGGTAAAGAGGTGAACATCATTGCCAAAATGGACGGATTGATTAAAGAGTTTATGGCTCATAAAGATGAGT
TTATCCTCTTTATTGATGAAGTGCATACCATTATGGGTACTGGAGTTGAGGGAAGTGCTCTTGACGTCGCTAATAGCTTG
AAACCAGCCTTATCTCGTGGGGAAATCTATCTTATTTCAGCTACCACAGCTGATGAGTTTATGATTATCGAACGAGATCC
AGCGATGGAACGACGTCTGCAACCAGTTTACGTTGATGAACTGGACAAAGAGGCATCTATTTTGGTCTTGAAAAAACGTC
GTCCCAAGTACAAACGAGAACTTGACATTGAAATTCCTAATGATGCCATTAAGGCAGCAGTAGAATTATCTATTCGTTAT
ATTACGGATAAAATGCTTCCAGATAAAGCTATTGATATTATTGATGAAGCTTCAGCGACTGCAAATATCGATGGGAAATC
AGAGATTACCTTAAGAGATATTGCGAGTGTCATACACCGTAAAAAAGGTATTCCTATGGAAAGTCTACTACGCACGTCTT
CAACTCCAGTGGATTTTGCGGAAGGGATGCGTGCTGTTGTTAAGGGGCAAGACCATGTGATTCGAACTATAGCACGCCTT
ATGTATAAAGGTATCCAGGGTGGGCAGAACAAGCGAAGACCTCTAGGAACTCTTCTTCTACTTGGAACAACAGGTACAGG
TAAAACTGAATTGGCGAAACAAGCAGCAAAACAACTGTTTGGTAGTGAAGAAGCGATGATTCGGCTGGATATGTCAGAAT
ACATGACTGATAATGCTGTTGTTCGTCTTATAGGAAATGACGAGCGAAAAGGTGACTTAACGGAAAAAATTAAGAAGAAT
CCCTACTCGTTAGTACTATTGGACGAGTTAGAAAAGGCTCATCCAGATGTCTGGGCTTTATATTTGCAAATGCTTGATGA
CGGGCATTTAACTGACGGACGTGGACGAAAAATCAATTTTAAGAATACGTTTATCATTGCAACATCAAACGTGGGGCATA
AGCGAATCAAAGATAAATATATCACCTCTGGTCAGACCTTTACAGAAATGAACAAGACTGACTATAAAGAGTTCATGAAG
GACATGAGAGACGAGTTAATCAAGATCTTTAAACGTCCTGAATTTATCAACCGTTGGAAAATTGAAGTGACTAATATCTT
GACGAAACAAACCATTGATAAGATTGTCTATTCAAAAATGGCTGTACATGAGAGCAGTTGGTTTAAAGAGCATCATATCC
TTATTAATTATGAGGATGTTATGGATGGTGACCAAACTATCGATGGCAAAAAATACTTCTATGAATATCTCAGTAGTGTC
GGTGTTAGCCCAGAAGATGGAGCAAGGCCTTTAGAGAGAACTATTGATGAAGTATTAACTGATGAAATCTTTGAGCAATT
GTATTTCCTTGGGCGAAAGCCACAAGATTACTTTATGGTTGATGTGTCTTTATCTGGACATGCACCAGGAACGTTTGCGT
ATGGTAACTCAGGTAGAAAGACAGTTCAAGATAGGCGTCAGACGCATATTAGTGTCAAACGGATACCTCCAGAGGAGTAT
GGTAACTATTTGCTTACTTCTTAA

Domains

Predicted by InterProScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(333-500)

ATPase family associated with various cellular activities (AAA) (AAA)

(58-183)

AAA lid domain (AAA_lid_9)

(203-280)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(550-588)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SHM8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae TIGR4

37.559

98.764

0.371
  clpE Streptococcus mutans UA159

37.599

97.836

0.368
  clpE Streptococcus pneumoniae Rx1

37.089

98.764

0.366
  clpE Streptococcus pneumoniae D39

37.089

98.764

0.366
  clpE Streptococcus pneumoniae R6

37.089

98.764

0.366
  clpC Lactococcus lactis subsp. cremoris KW2

36.909

97.991

0.362