Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE1   Type   Regulator
Locus tag   ACJWMC_RS07880 Genome accession   NZ_CP177181
Coordinates   1704930..1705667 (-) Length   245 a.a.
NCBI ID   WP_002891534.1    Uniprot ID   J7T4Q1
Organism   Streptococcus salivarius strain MRD1919     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1699930..1710667
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMC_RS07860 - 1701252..1701500 (-) 249 WP_002884680.1 KH domain-containing protein -
  ACJWMC_RS07865 rpsP 1701512..1701784 (-) 273 WP_002884675.1 30S ribosomal protein S16 -
  ACJWMC_RS07870 - 1701949..1703328 (-) 1380 WP_037598350.1 hypothetical protein -
  ACJWMC_RS07875 - 1703440..1704618 (-) 1179 WP_037598353.1 sensor histidine kinase -
  ACJWMC_RS07880 comE/comE1 1704930..1705667 (-) 738 WP_002891534.1 LytR/AlgR family response regulator transcription factor Regulator
  ACJWMC_RS07885 - 1705881..1707203 (+) 1323 WP_002891535.1 matrixin family metalloprotease -
  ACJWMC_RS07890 tehB 1707982..1708860 (+) 879 WP_037598358.1 SAM-dependent methyltransferase TehB -
  ACJWMC_RS07895 - 1708943..1709695 (-) 753 WP_037598361.1 DUF4767 domain-containing protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28060.04 Da        Isoelectric Point: 4.7802

>NTDB_id=969737 ACJWMC_RS07880 WP_002891534.1 1704930..1705667(-) (comE/comE1) [Streptococcus salivarius strain MRD1919]
MLSIIVLEDDALQRHRVGRLLDEAVEESKAVVDGITFYEQGQELLDADRGSGKSMVYLLDIDLKNQTKQGLDIGLEIRKE
DLKAQIAFVTAYSEFMPLTFRYKIQALDFVDKSMEDVDLKRALVELLDFAYSQVEQETKAQSLTVKTDKNDVNIPYDDIL
YIETAPVPHKLIAHTKSNLVEFYGKIAEVAKLDDIFFQTHRSFVVNVNNVTSVDRTANMVFFEGNESCLLSRTRKKELLE
RLKNR

Nucleotide


Download         Length: 738 bp        

>NTDB_id=969737 ACJWMC_RS07880 WP_002891534.1 1704930..1705667(-) (comE/comE1) [Streptococcus salivarius strain MRD1919]
ATGCTTTCTATTATCGTCCTTGAAGATGATGCCTTGCAGCGTCATCGTGTTGGTCGTTTATTGGACGAAGCAGTTGAGGA
GTCGAAGGCCGTTGTTGATGGGATTACTTTTTATGAACAGGGTCAGGAATTGTTAGATGCTGATAGAGGTTCGGGTAAAT
CCATGGTTTATCTTTTGGATATTGACCTTAAAAATCAAACTAAGCAGGGACTAGATATTGGGCTTGAAATCCGTAAGGAA
GACTTGAAAGCACAAATTGCCTTTGTTACAGCTTACTCGGAGTTTATGCCCTTGACCTTCCGTTATAAGATTCAAGCTCT
AGATTTTGTCGATAAATCCATGGAAGATGTGGATCTTAAGAGAGCTTTAGTAGAACTTTTAGATTTTGCTTATTCACAGG
TTGAGCAAGAAACCAAGGCACAGAGTCTAACTGTTAAAACGGATAAAAATGATGTTAATATTCCTTATGATGATATTTTA
TACATTGAGACAGCCCCTGTGCCACATAAGTTAATCGCTCATACCAAGTCAAACCTAGTGGAATTCTATGGGAAAATTGC
AGAAGTAGCAAAATTGGATGATATTTTCTTCCAAACGCACCGCTCTTTTGTTGTCAATGTGAATAATGTGACAAGTGTGG
ATCGTACAGCTAATATGGTCTTCTTTGAGGGAAACGAGTCATGCCTCCTATCGCGGACACGTAAAAAGGAACTTTTGGAA
CGTTTGAAAAATCGTTAG

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(152-242)

Response regulator receiver domain (Response_reg)

(4-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7T4Q1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE1 Streptococcus equinus JB1

37.449

99.184

0.371