Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexA   Type   Machinery gene
Locus tag   ACJVC4_RS00250 Genome accession   NZ_CP177179
Coordinates   51326..53857 (+) Length   843 a.a.
NCBI ID   WP_411893052.1    Uniprot ID   -
Organism   Streptococcus salivarius strain MRD-NRLLH     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 46326..58857
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJVC4_RS00230 purB 46498..47796 (+) 1299 WP_002889582.1 adenylosuccinate lyase -
  ACJVC4_RS00235 argS 48673..50364 (-) 1692 WP_002889584.1 arginine--tRNA ligase -
  ACJVC4_RS00240 argR 50519..50947 (+) 429 WP_186821380.1 arginine repressor -
  ACJVC4_RS00245 - 50947..51306 (+) 360 WP_002889586.1 YlbF family regulator -
  ACJVC4_RS00250 hexA 51326..53857 (+) 2532 WP_411893052.1 DNA mismatch repair protein MutS Machinery gene
  ACJVC4_RS00255 - 53891..54346 (-) 456 WP_002889588.1 DUF3021 domain-containing protein -
  ACJVC4_RS00260 - 54343..54780 (-) 438 WP_002889589.1 LytTR family DNA-binding domain-containing protein -
  ACJVC4_RS00265 - 54959..55264 (+) 306 WP_002889590.1 hypothetical protein -
  ACJVC4_RS00270 hexB 55316..57253 (+) 1938 WP_002889591.1 DNA mismatch repair endonuclease MutL Machinery gene
  ACJVC4_RS00275 - 57384..57605 (+) 222 WP_037597288.1 hypothetical protein -

Sequence

Protein


Download         Length: 843 a.a.        Molecular weight: 94607.60 Da        Isoelectric Point: 4.6314

>NTDB_id=969422 ACJVC4_RS00250 WP_411893052.1 51326..53857(+) (hexA) [Streptococcus salivarius strain MRD-NRLLH]
MQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQSYIDVLVEMGYKVAIA
EQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKAGSRFGLAYMDVSTGEFFATELDDSSSVCSEIQNLK
AREVVVGYDLSEADEQVLVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQKAQHYEIKDY
LQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQATITERQNIIQVFLDNFFERSDLTESL
KGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILDSFNDEALSRLLQELDALPELESLIRSAIDPDAPATITEG
GIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREVSGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKATLKNSERFG
TAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVVAETNHYVRPIFNDEHRIVIDQ
GRHAVVEKVMGVQEYIPNTITFDSQTNIQLITGPNMSGKSTYMRQLALSVVMAQMGSYVPADSIDLPVFDAIYTRIGAAD
DLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHELTALSNTLTH
LVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPTDLLERADTILTQLEGETVAIQPQEKVLPQEKPATETHV
NEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide


Download         Length: 2532 bp        

>NTDB_id=969422 ACJVC4_RS00250 WP_411893052.1 51326..53857(+) (hexA) [Streptococcus salivarius strain MRD-NRLLH]
ATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTCTTCCGTATGGGTGATTTTTACGAATTATT
TTATGATGATGCCGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACCAGTCGTAATAAGAACGCCGATAATCCTATTC
CTATGGCTGGTGTTCCTTACCATTCAGCTCAATCCTATATTGATGTCTTGGTTGAGATGGGCTACAAGGTAGCCATTGCT
GAGCAGATGGAGGATCCTAAACAGGCTGTTGGTGTGGTTAAGCGTGAGGTGGTTCAGGTTATCACGCCAGGGACAGTGGT
TGACAGTTCTAAACCTGATAATGCCAACAATTTCTTGGTAGCCATTGACAAGGCTGGAAGTCGATTCGGCCTGGCCTATA
TGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGACGATTCCAGTTCAGTTTGTAGTGAAATTCAGAACCTTAAG
GCACGTGAAGTAGTGGTTGGGTATGATTTATCTGAAGCTGATGAACAAGTTTTGGTGAAGCAACTCAACCTGCTTCTCTC
CAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACTAGTTTGACAGACTTGGAAAGCAGTGTGGCGGGTAAAC
TTCTCCAGTATGTTCATCGTACTCAGATGCGAGAGCTCAGTCATTTACAAAAGGCACAGCACTATGAGATTAAGGATTAC
TTGCAGATGTCCTATGCGACCAAGTCAAGTTTGGATTTACTAGAAAATGCTAGAACGGGCAAGAAACACGGATCTCTTTT
CTGGCTCTTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTGCGAACTTGGATTGATCGTCCTTTAGTGAATCAAG
CCACTATCACCGAGCGTCAGAATATCATCCAAGTTTTCTTGGACAATTTCTTTGAGCGTAGTGACTTGACTGAGAGTCTA
AAAGGTGTTTACGATATTGAGCGCCTGGCCAGTCGTGTTTCCTTTGGCAAGGCTAATCCAAAAGATTTGATTCAGCTAGG
TCATACTTTGGCTCAAGTACCGGTGATTAAGGCGATTTTGGATTCTTTTAATGATGAGGCCTTGTCACGTCTTTTACAAG
AGTTAGATGCTCTGCCAGAATTAGAGAGTTTGATTCGGTCGGCTATTGATCCAGATGCTCCTGCAACCATTACAGAAGGT
GGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGATGAGTGAGGGAACCTCATGGATCGCAGA
TATCGAAGCTAAAGAACGTGAAGTATCTGGTATTACAACACTAAAGATTGATTATAACCGTAAAGATGGTTATTACTTCC
ATGTGACTAACTCTAACCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCAACCCTGAAAAATTCAGAGCGCTTTGGA
ACTGCTGAGTTGGCTAAGATAGAAGGTGAAATGCTCGAGGCACGTGAAAAGTCATCAACGCTAGAGTATGATATTTTCAT
GCGTGTCCGTGAGCAGGTTGAACGCTATATTGACCGTTTGCAATCTTTGGCTAAAGCTATTGCGACAGTCGATGTGCTTC
AGAGTCTAGCTGTTGTAGCAGAGACCAATCATTATGTTCGCCCTATTTTCAATGATGAGCATCGTATTGTTATTGATCAA
GGCCGTCATGCAGTGGTTGAGAAGGTTATGGGAGTTCAAGAATACATCCCAAACACCATTACCTTTGACAGTCAGACCAA
TATTCAGCTCATCACAGGACCAAATATGAGTGGTAAATCCACCTATATGCGTCAGTTAGCCTTATCAGTAGTTATGGCTC
AGATGGGGTCTTACGTGCCAGCAGATAGTATTGACTTGCCAGTTTTTGATGCTATCTATACACGTATTGGTGCTGCAGAT
GACCTGATTTCAGGGCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAATCAGGCCATTAAGCGAGCGACACCTAATTC
CTTGATTATTTTTGATGAGTTGGGACGTGGGACAGCCACCTATGACGGTATGGCTCTGGCCCAGTCTATCATTGAGTTTA
TTCATGACAAGGTGGGGGCTAAAACCATGTTTGCGACCCATTATCATGAGTTGACAGCTCTGTCAAATACTTTGACACAC
CTTGTCAACGTTCATGTGGCGACACTTGAAAAGGATGGTGAGGTGACTTTCCTTCACAAGATTGTCGATGGCCCAGCTGA
CAAATCTTATGGTATTCATGTGGCTAAGATTGCAGGTTTACCAACAGATCTACTGGAACGTGCTGACACCATCTTGACAC
AACTAGAGGGCGAGACAGTTGCTATTCAACCTCAGGAAAAGGTATTGCCTCAAGAGAAGCCTGCCACTGAAACACATGTC
AACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCAGTTCTTCAAGAGTTGCGTGATTTAGACATTTACAACAT
GACACCTATGCAAGTCATGATGGCTGTAGCAGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

MutS family domain IV (MutS_IV)

(406-496)

MutS domain III (MutS_III)

(247-537)

MutS domain V (MutS_V)

(590-776)

MutS domain II (MutS_II)

(117-230)

MutS domain I (MutS_I)

(1-109)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexA Streptococcus pneumoniae R6

73.934

100

0.74
  mutS Pseudomonas stutzeri strain ATCC 17587

36.195

100

0.37