Detailed information NTG0968259

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: MKY56_RS18425
• Genome accession: NZ_CP150257
• Coordinates: 3531306..3532463 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus sp. FSL M8-0054
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3526306..3537463

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MKY56_RS18395 (MKY56_18395)	-	3526559..3526978 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
MKY56_RS18400 (MKY56_18400)	comFC	3527052..3527774 (-)	723	WP_003227991.1	comF operon protein ComFC	Machinery gene
MKY56_RS18405 (MKY56_18405)	comFB	3527738..3528034 (-)	297	WP_003227989.1	late competence protein ComFB	-
MKY56_RS18410 (MKY56_18410)	comFA	3528094..3529485 (-)	1392	WP_003243962.1	ATP-dependent helicase ComFA	Machinery gene
MKY56_RS18415 (MKY56_18415)	-	3529591..3530436 (-)	846	WP_003244125.1	DegV family protein	-
MKY56_RS18420 (MKY56_18420)	degU	3530534..3531223 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
MKY56_RS18425 (MKY56_18425)	degS	3531306..3532463 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
MKY56_RS18430 (MKY56_18430)	-	3532680..3533333 (+)	654	WP_003227979.1	YigZ family protein	-
MKY56_RS18435 (MKY56_18435)	tagV	3533333..3534508 (+)	1176	WP_003244117.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
MKY56_RS18440 (MKY56_18440)	-	3534581..3535657 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
MKY56_RS18445 (MKY56_18445)	-	3535802..3536995 (-)	1194	WP_003243252.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=968259 MKY56_RS18425 WP_003227983.1 3531306..3532463(-) (degS) [Bacillus sp. FSL M8-0054]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=968259 MKY56_RS18425 WP_003227983.1 3531306..3532463(-) (degS) [Bacillus sp. FSL M8-0054]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTCCGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1