Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   MKY62_RS06235 Genome accession   NZ_CP150217
Coordinates   1252205..1252843 (+) Length   212 a.a.
NCBI ID   WP_003180627.1    Uniprot ID   A0A6I7TLB4
Organism   Bacillus sp. FSL R7-0646     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1247205..1257843
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MKY62_RS06205 (MKY62_06205) - 1247844..1248920 (+) 1077 WP_151025719.1 ABC transporter ATP-binding protein -
  MKY62_RS06210 (MKY62_06210) - 1248922..1249845 (+) 924 WP_003180617.1 ATP-binding cassette domain-containing protein -
  MKY62_RS06215 (MKY62_06215) - 1250075..1250653 (+) 579 WP_003180619.1 GNAT family N-acetyltransferase -
  MKY62_RS06220 (MKY62_06220) spxA 1250831..1251226 (+) 396 WP_003180621.1 transcriptional regulator SpxA -
  MKY62_RS06225 (MKY62_06225) - 1251257..1251919 (-) 663 WP_339613993.1 TerC family protein -
  MKY62_RS06230 (MKY62_06230) - 1252095..1252223 (+) 129 Protein_1172 hypothetical protein -
  MKY62_RS06235 (MKY62_06235) mecA 1252205..1252843 (+) 639 WP_003180627.1 adaptor protein MecA Regulator
  MKY62_RS06240 (MKY62_06240) - 1253081..1254385 (+) 1305 WP_003180630.1 glycosyl hydrolase family 8 -
  MKY62_RS06245 (MKY62_06245) - 1254509..1255624 (+) 1116 WP_080989013.1 tripartite tricarboxylate transporter substrate binding protein -
  MKY62_RS06250 (MKY62_06250) - 1255725..1256180 (+) 456 WP_003180634.1 tripartite tricarboxylate transporter TctB family protein -
  MKY62_RS06255 (MKY62_06255) - 1256203..1257708 (+) 1506 WP_003180636.1 tripartite tricarboxylate transporter permease -

Sequence

Protein


Download         Length: 212 a.a.        Molecular weight: 25044.99 Da        Isoelectric Point: 4.1840

>NTDB_id=966646 MKY62_RS06235 WP_003180627.1 1252205..1252843(+) (mecA) [Bacillus sp. FSL R7-0646]
MEIERINEHTVKFYISYGDIEDRGFDREEIWYNRERSEELFWEMMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTRAQL
SKDGQKLELPIPEDKKQHVAEESLDALLDDFQKEEQAEEQKLQFVLKFDDFEDLISLSKMSISGCQTTLYSHENRYYLFV
DFSELPDEEVENQLSILLEYASESKTTIHMLKEYGTLIAADHALHTIKKHFA

Nucleotide


Download         Length: 639 bp        

>NTDB_id=966646 MKY62_RS06235 WP_003180627.1 1252205..1252843(+) (mecA) [Bacillus sp. FSL R7-0646]
ATGGAAATCGAAAGAATAAACGAACACACGGTTAAGTTTTATATTTCCTACGGTGATATCGAAGACCGCGGGTTTGACAG
AGAAGAAATTTGGTACAATCGAGAACGCAGTGAAGAGCTTTTTTGGGAAATGATGGACGAAGTGCACGAAGAAGAAGAGT
TTGCCGTTGAAGGCCCCCTTTGGATTCAAGTGCAGGCCCTTGATAAGGGATTGGAAATCATTGTGACAAGAGCTCAGCTG
TCCAAAGACGGACAAAAGCTGGAACTGCCGATTCCTGAAGATAAAAAACAGCATGTAGCAGAAGAAAGCCTTGATGCTTT
GCTTGACGACTTTCAAAAAGAAGAGCAGGCAGAAGAGCAGAAACTGCAGTTTGTTTTAAAGTTTGACGATTTTGAGGATT
TAATCTCACTGTCAAAAATGTCTATCAGCGGCTGCCAAACGACATTGTACTCTCACGAGAACCGCTATTATTTATTCGTG
GATTTCAGTGAACTGCCCGATGAAGAGGTGGAAAACCAGCTGAGCATTCTGCTGGAGTATGCCTCAGAATCAAAGACGAC
GATTCATATGCTGAAAGAGTATGGAACACTGATTGCAGCGGATCATGCTCTTCATACAATAAAAAAGCACTTCGCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6I7TLB4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

82.028

100

0.84

Multiple sequence alignment