Detailed information NTG0966068

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: NSQ79_RS00520
• Genome accession: NZ_CP150200
• Coordinates: 85630..88080 (+)
• Length: 816 a.a.
• NCBI ID: WP_049529353.1
• Uniprot ID: A0A6G4ND74
• Organism: Streptococcus sp. FSL W7-1342
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 80630..93080

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NSQ79_RS00495 (NSQ79_00495)	ahpC	81564..82124 (-)	561	WP_049529352.1	alkyl hydroperoxide reductase subunit C	-
NSQ79_RS00500 (NSQ79_00500)	rpsB	82397..83164 (+)	768	WP_002886342.1	30S ribosomal protein S2	-
NSQ79_RS00505 (NSQ79_00505)	tsf	83275..84315 (+)	1041	WP_002886343.1	translation elongation factor Ts	-
NSQ79_RS00510 (NSQ79_00510)	-	84422..84892 (-)	471	WP_004182164.1	small multi-drug export protein	-
NSQ79_RS00515 (NSQ79_00515)	-	85174..85629 (+)	456	WP_014633783.1	CtsR family transcriptional regulator	-
NSQ79_RS00520 (NSQ79_00520)	clpC	85630..88080 (+)	2451	WP_049529353.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
NSQ79_RS00525 (NSQ79_00525)	pbp3	88209..89465 (-)	1257	WP_002886347.1	D-alanyl-D-alanine carboxypeptidase PBP3	-
NSQ79_RS00530 (NSQ79_00530)	pbp3	89610..90857 (-)	1248	WP_045002006.1	D-alanyl-D-alanine carboxypeptidase PBP3	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90356.67 Da
• Isoelectric Point: 5.7203

>NTDB_id=966068 NSQ79_RS00520 WP_049529353.1 85630..88080(+) (clpC) [Streptococcus sp. FSL W7-1342]
MTTYSRKMQAIFHRAQLEAERFGSPFLETWHVLLAMVEVPGSVAYLTFTDFEDRIRAEEIETATVLAMEKSPKDLSESDI
IDLRAQSHALEVMLQEAEGIASVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERYAGLS
KQDLKAIHDLRKPKKSKASGNFANMMQPPQSSTGELSDYTKDLTAVAESGALDPVIGREKEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVPEAIDILKGLRSSYEDYHRVTI
TDEAVETAVKAAHRYLTSKNLPDSAIDLLDEASATVQGRIKKEAKREITPLDEALLSGDMKAAVKQYKASQKAKLPEPAL
VDADQIMQTLSRLSGIPVEKMTQADSKRYLNLEAELHKRVIGQDEAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNIL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTIGFGAQDISHNHQAMQSRIMEELKKAYRPEFINRIDEKVV
FHSLEEEQLREIVKIMMKPLVSALAEKGIDLKFQPAALKHLAKDGYDVEMGARPLRRTIQTQVEDKLSELLLGGQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide

• Length: 2451 bp

>NTDB_id=966068 NSQ79_RS00520 WP_049529353.1 85630..88080(+) (clpC) [Streptococcus sp. FSL W7-1342]
ATGACGACATATTCAAGAAAAATGCAGGCCATTTTCCATCGTGCTCAGCTTGAGGCAGAGCGTTTTGGAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTGGCTATGGTTGAGGTTCCAGGATCTGTAGCCTACCTAACATTTACTGATTTTGAGGACC
GTATTCGTGCGGAAGAGATTGAGACAGCCACTGTACTAGCGATGGAGAAAAGTCCAAAAGACTTGTCTGAATCCGATATT
ATCGATTTACGTGCACAGTCACATGCTTTAGAGGTTATGTTGCAAGAGGCAGAGGGAATTGCTAGTGTGACTGGTGCTGT
AGAGGTAGGGTCTGAACATGTATTGATGGCCTTCCTTCTTCATAAGGATTTGATGGTTTGTCGTCTCCTTGAAGTTGCTG
GTTTTCAATATAAGGATGACAGCGATAAGCCTCGCATTATCGATTTACGACGTTCTTTGGAGCGTTACGCAGGTCTTAGT
AAGCAAGATTTGAAGGCCATTCATGACCTTCGTAAGCCTAAAAAATCAAAGGCATCAGGAAATTTTGCTAATATGATGCA
GCCTCCTCAATCTTCTACTGGGGAACTGTCAGATTATACCAAGGACTTAACGGCAGTAGCCGAGTCAGGTGCTCTTGATC
CTGTTATCGGACGTGAGAAAGAAATTTCACGCATGATTCAGGTTTTGAGTCGTAAAACGAAGAATAACCCAGTTCTTGTG
GGTGAAGCAGGTGTTGGTAAGACGGCACTTGCGCTTGGCTTAGCACAGCGTATTGCTTCAGGCGAAGTACCTTTTGAGTT
GGCTGATATGCGTATCTTAGAGCTTGATATGATGAGTGTGGTTGCAGGAACACGTTTCCGTGGCGATTTCGAAGAACGTA
TGAATCAGATCATTGATGAGATTGAAGCTGATGGAAAAATCATTCTTTTTATTGACGAATTGCATACGATTATTGGTTCT
GGTTCAGGTATTGATAGCACCTTAGATGCGGCGAATATTTTGAAACCCGCTCTAGCACGTGGAACTCTTCATATGGTTGG
AGCAACTACTCAAGCTGAGTACCAGAAGCATATTGAGAAAGATGCAGCTCTTTCTCGCCGTTTTGCTAAGATTACAATTG
AGGAGCCAAGTGTACCTGAGGCGATTGATATTCTAAAAGGCCTACGTTCGTCTTATGAAGACTATCATCGTGTAACGATT
ACTGATGAGGCGGTTGAGACAGCAGTCAAGGCAGCCCACCGTTATTTGACGAGTAAAAACTTGCCTGACTCTGCCATTGA
TCTTTTAGATGAAGCGAGTGCAACTGTTCAAGGTCGTATCAAAAAAGAAGCCAAACGTGAGATAACGCCTTTGGATGAAG
CGCTTCTATCTGGTGATATGAAGGCTGCTGTTAAACAATATAAAGCTAGCCAAAAAGCAAAATTACCAGAACCTGCCTTG
GTAGATGCAGATCAGATTATGCAAACCCTTAGTCGTCTATCAGGTATTCCTGTTGAGAAGATGACTCAGGCAGATAGCAA
GCGTTACTTGAATCTGGAAGCAGAGCTTCATAAACGTGTTATTGGTCAAGACGAAGCAGTTTCAGCGATTAGTCGTGCTA
TTCGTCGTAACCAGTCAGGTATTCGTACTGGAAAACGTCCGATTGGTTCCTTCATGTTCCTTGGACCTACTGGTGTTGGT
AAGACAGAGTTGGCCAAGGCTTTGGCGGAAGTTCTCTTTGATGATGAGTCAGCTTTGCTTCGCTTTGACATGTCAGAATA
CATGGAAAAATTTGCGGCTAGCCGCCTTAATGGTGCTCCTCCAGGTTATGTTGGATATGATGAGGGTGGTGAATTAACAG
AGAAAGTTCGCAATAAGCCTTACTCAGTTCTCCTCTTTGACGAGGTGGAAAAGGCTCACCCAGATATTTTCAACATCCTC
TTACAGGTTTTGGATGATGGTGTCTTGACGGATAGTCGAGGTCGTAAAGTCGATTTCTCAAATACCATTATCATTATGAC
TTCGAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACTATTGGATTTGGTGCTCAAGATATTTCTCATAATCACCAAG
CAATGCAGTCACGTATCATGGAAGAACTTAAGAAGGCCTACCGTCCAGAGTTTATCAACCGTATTGATGAGAAGGTTGTC
TTCCATAGTCTAGAGGAAGAGCAACTTCGTGAGATTGTCAAGATTATGATGAAACCGTTGGTATCAGCTTTGGCTGAAAA
AGGGATTGACTTGAAATTCCAACCAGCTGCTCTCAAGCATTTAGCTAAAGATGGCTATGATGTTGAGATGGGTGCTCGTC
CATTACGTCGCACGATTCAAACTCAAGTGGAGGACAAGTTATCTGAGCTCTTACTAGGTGGTCAAGTAGTTAGTGGACAA
ACTCTTAAAATCGGCTGCTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (724-804)

• AAA domain (Cdc48 subfamily) (AAA_2) (546-717)

• ATPase family associated with various cellular activities (AAA) (AAA) (238-370)

• AAA lid domain (AAA_lid_9) (378-457)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (108-135)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

3D structure

• AlphaFold DB: A0A6G4ND74

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus thermophilus LMG 18311	94.853	100	0.949
clpC	Streptococcus thermophilus LMD-9	94.73	100	0.947
clpC	Streptococcus mutans UA159	72.549	100	0.725
clpC	Streptococcus pneumoniae TIGR4	67.157	100	0.672
clpC	Streptococcus pneumoniae Rx1	67.034	100	0.67
clpC	Streptococcus pneumoniae D39	67.034	100	0.67
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.421	100	0.513
clpC	Bacillus subtilis subsp. subtilis str. 168	47.388	100	0.478
clpE	Streptococcus mutans UA159	47.764	76.716	0.366