Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACJJVF_RS09490 Genome accession   NZ_CP175682
Coordinates   1977322..1977978 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain Z1324PEC0010     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1972322..1982978
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJJVF_RS09455 dcyD 1973201..1974187 (+) 987 WP_001128218.1 D-cysteine desulfhydrase -
  ACJJVF_RS09460 tcyL 1974202..1974870 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  ACJJVF_RS09465 tcyN 1974867..1975619 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  ACJJVF_RS09470 sdiA 1975849..1976571 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  ACJJVF_RS09475 yecF 1976639..1976863 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  ACJJVF_RS09480 yecU 1976850..1977026 (-) 177 WP_000590347.1 protein YecU -
  ACJJVF_RS09485 - 1977109..1977180 (-) 72 Protein_1853 transcriptional regulator -
  ACJJVF_RS09490 letA 1977322..1977978 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ACJJVF_RS09495 uvrC 1977975..1979807 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ACJJVF_RS09500 pgsA 1979864..1980412 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACJJVF_RS09520 yecA 1981062..1981728 (+) 667 Protein_1857 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=966068 ACJJVF_RS09490 WP_000611335.1 1977322..1977978(+) (letA) [Escherichia coli strain Z1324PEC0010]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=966068 ACJJVF_RS09490 WP_000611335.1 1977322..1977978(+) (letA) [Escherichia coli strain Z1324PEC0010]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment