Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACI6TB_RS02895 Genome accession   NZ_CP174270
Coordinates   582807..584636 (+) Length   609 a.a.
NCBI ID   WP_406812505.1    Uniprot ID   -
Organism   Histophilus somni strain HSNMG-1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 577807..589636
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACI6TB_RS02865 (ACI6TB_02865) - 578624..578974 (-) 351 WP_075321429.1 RidA family protein -
  ACI6TB_RS02870 (ACI6TB_02870) - 579085..579807 (+) 723 WP_011608810.1 YwiC-like family protein -
  ACI6TB_RS02875 (ACI6TB_02875) - 579822..580721 (+) 900 WP_012341793.1 RimK family alpha-L-glutamate ligase -
  ACI6TB_RS02880 (ACI6TB_02880) lpxK 580840..581835 (+) 996 WP_406812503.1 tetraacyldisaccharide 4'-kinase -
  ACI6TB_RS02885 (ACI6TB_02885) - 581832..582029 (+) 198 WP_011608813.1 Trm112 family protein -
  ACI6TB_RS02890 (ACI6TB_02890) kdsB 582044..582814 (+) 771 WP_406812504.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  ACI6TB_RS02895 (ACI6TB_02895) uvrC 582807..584636 (+) 1830 WP_406812505.1 excinuclease ABC subunit UvrC Machinery gene
  ACI6TB_RS02900 (ACI6TB_02900) - 584702..585088 (-) 387 WP_011608816.1 TM2 domain-containing protein -
  ACI6TB_RS02905 (ACI6TB_02905) rnb 585213..587192 (-) 1980 WP_406812506.1 exoribonuclease II -
  ACI6TB_RS02910 (ACI6TB_02910) - 587257..588045 (-) 789 WP_406812507.1 enoyl-ACP reductase -
  ACI6TB_RS02915 (ACI6TB_02915) - 588136..588891 (-) 756 WP_406812508.1 Nif3-like dinuclear metal center hexameric protein -

Sequence

Protein


Download         Length: 609 a.a.        Molecular weight: 68980.09 Da        Isoelectric Point: 9.1702

>NTDB_id=964758 ACI6TB_RS02895 WP_406812505.1 582807..584636(+) (uvrC) [Histophilus somni strain HSNMG-1]
MFDAKNFLANVTHQPGVYRMFDEKGQVIYVGKAKDLKKRLSSYFRTNLNSKKTSALVSHIHSIETTITASETEALLLEHN
YIKAFQPRYNVLLRDDKSYPYILLTKERHPRITSHRGSKKVQGEYFGPYPHAGAVRETLSLLQKLFPIRQCENSVYNNRS
RPCLQYQIGRCSGPCIDGLVSDEEYQQQVDFARLFLQGKDQQVLEHLIKKMEQASMQLNFEQAAYFRDQIQAIRAVIEKQ
FVSNERLDDMDILAIAYQLGIACVQVLFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQFYLQGHQGRIIPSTIIVDHV
LNEKHELEVLLTEQAGRKVNIQDNVKGNKSKFLHLAQMNAQAALVTQLKQANLIQERYQALQELLSLTTIKRMECFDISH
TMGEQTIASCVVFDTEGPLKSDYRRFNISGITAGDDYAAMEQALLKRYDRPLENEKIPDIIFIDGGKGQLNRALQVFAQL
DVSWDKNKPLLIGVAKGVERKAGLETLIISKQNKEVNLLPDSLALHLIQHIRDESHHHAIGGHRKKRQQAFTQSGLEAIE
GVGAKRRQALLKYLGGMQGVKNATLAEISSVPGISAALAERIYETLRSE

Nucleotide


Download         Length: 1830 bp        

>NTDB_id=964758 ACI6TB_RS02895 WP_406812505.1 582807..584636(+) (uvrC) [Histophilus somni strain HSNMG-1]
ATGTTTGATGCCAAAAACTTTCTTGCCAATGTAACGCACCAGCCCGGTGTATACCGAATGTTTGATGAAAAAGGGCAGGT
GATTTATGTTGGTAAGGCAAAAGATTTGAAAAAGCGTTTATCCAGCTATTTTCGCACTAATTTGAACAGTAAAAAAACTT
CCGCACTGGTTTCGCATATTCATTCAATAGAAACAACAATCACCGCTTCAGAAACTGAAGCGTTATTGCTTGAACATAAT
TATATTAAAGCTTTTCAGCCCCGTTACAATGTTTTATTACGTGATGATAAATCCTATCCCTATATTCTATTAACGAAAGA
ACGTCATCCTAGAATTACCTCGCATCGAGGTTCAAAAAAAGTACAAGGTGAATATTTTGGCCCTTATCCCCACGCAGGAG
CGGTACGTGAAACTCTCTCTTTGTTGCAAAAATTATTTCCTATTCGGCAGTGTGAAAACTCGGTATATAACAACCGCTCT
CGCCCTTGTTTGCAGTATCAAATCGGACGTTGCAGTGGTCCTTGTATTGATGGTTTAGTATCTGATGAAGAATATCAGCA
ACAGGTCGATTTTGCTCGGCTATTTTTACAAGGTAAAGATCAGCAAGTGTTGGAGCATTTGATCAAAAAAATGGAACAAG
CAAGTATGCAACTTAATTTTGAGCAGGCAGCTTATTTCCGTGATCAAATTCAGGCGATTCGTGCGGTAATTGAAAAACAA
TTTGTTTCTAACGAACGTTTAGATGATATGGATATTCTGGCAATTGCTTATCAGCTTGGTATTGCTTGTGTACAAGTTTT
ATTTATTCGTCAGGGAAAAGTATTAGGTAATCGCAGTTATTTTCCCAAAGTACCGGCAAATACGGATTTAAGTGAATTAA
CCGAAACGTTTGTCGGACAGTTTTATTTACAGGGGCATCAAGGTCGGATTATACCAAGTACCATTATTGTTGATCATGTT
TTGAATGAAAAACATGAACTTGAGGTTTTATTAACAGAACAAGCTGGACGTAAAGTAAATATTCAAGATAATGTGAAAGG
CAATAAAAGCAAATTTTTACATCTGGCTCAAATGAATGCACAAGCCGCATTAGTAACACAGCTTAAACAAGCTAATTTAA
TACAAGAGCGTTATCAGGCATTACAAGAACTTTTGTCTTTAACTACCATTAAACGTATGGAATGTTTTGATATCAGTCAT
ACTATGGGAGAGCAAACAATAGCTTCTTGCGTTGTTTTTGATACTGAAGGACCGTTGAAATCAGATTATCGTCGTTTCAA
CATAAGCGGAATTACTGCAGGCGATGATTATGCCGCTATGGAGCAGGCTTTGTTGAAACGTTATGATCGCCCATTAGAAA
ATGAGAAAATTCCAGATATTATTTTTATTGATGGGGGAAAGGGGCAATTAAACCGTGCTTTACAAGTTTTTGCACAATTA
GATGTCTCTTGGGATAAAAATAAACCGCTCTTAATTGGGGTAGCAAAAGGGGTAGAGCGTAAAGCAGGTTTAGAGACGTT
AATTATTAGTAAACAAAATAAGGAAGTGAATTTACTGCCTGACAGCCTTGCCCTTCATCTTATTCAACATATTCGTGATG
AAAGTCATCATCATGCCATTGGCGGTCATCGTAAAAAACGTCAACAGGCTTTTACTCAAAGCGGTCTAGAAGCCATTGAA
GGTGTTGGAGCAAAACGAAGACAAGCTTTATTAAAATATTTAGGGGGCATGCAAGGTGTAAAAAATGCGACTTTAGCAGA
AATTTCCTCCGTTCCGGGCATTTCTGCTGCGTTGGCGGAACGGATTTATGAAACGCTAAGAAGTGAATAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(556-607)

UvrB/uvrC motif (UVR)

(202-235)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(382-540)

GIY-YIG catalytic domain (GIY-YIG)

(15-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

36.529

99.343

0.363