Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   NYE79_RS06930 Genome accession   NZ_CP150168
Coordinates   1375718..1377976 (+) Length   752 a.a.
NCBI ID   WP_339293650.1    Uniprot ID   -
Organism   Streptococcus sp. FSL W8-0197     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1370718..1382976
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE79_RS06900 (NYE79_06900) - 1371502..1372275 (-) 774 WP_339293647.1 HAD hydrolase family protein -
  NYE79_RS06905 (NYE79_06905) - 1372280..1373137 (-) 858 WP_339293648.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  NYE79_RS06910 (NYE79_06910) - 1373286..1373606 (-) 321 WP_339293649.1 TfoX/Sxy family protein -
  NYE79_RS06915 (NYE79_06915) - 1373640..1374374 (-) 735 WP_000140925.1 amino acid ABC transporter ATP-binding protein -
  NYE79_RS06920 (NYE79_06920) - 1374374..1375057 (-) 684 WP_001011622.1 amino acid ABC transporter permease -
  NYE79_RS06925 (NYE79_06925) - 1375249..1375479 (+) 231 WP_000443577.1 DUF1797 family protein -
  NYE79_RS06930 (NYE79_06930) clpE 1375718..1377976 (+) 2259 WP_339293650.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  NYE79_RS06935 (NYE79_06935) - 1378019..1378633 (-) 615 WP_339293651.1 GyrI-like domain-containing protein -
  NYE79_RS06940 (NYE79_06940) - 1378688..1379590 (-) 903 WP_000841079.1 YafY family protein -
  NYE79_RS06945 (NYE79_06945) - 1379767..1380219 (+) 453 WP_000013174.1 NUDIX hydrolase -
  NYE79_RS06950 (NYE79_06950) - 1380278..1380577 (+) 300 WP_000767208.1 DUF1827 family protein -
  NYE79_RS06955 (NYE79_06955) metK 1380648..1381838 (-) 1191 WP_000003912.1 methionine adenosyltransferase -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83975.54 Da        Isoelectric Point: 5.1830

>NTDB_id=964618 NYE79_RS06930 WP_339293650.1 1375718..1377976(+) (clpE) [Streptococcus sp. FSL W8-0197]
MLCQNCKINDSTIHLYTNINGQQKQIDLCQNCYKIIKTDPKNTLFKGMTDLNNRDFDPFGDFFNDLNNFKPSSNNVPPTQ
SGGGYGGNGGYGPQNRGPLQTPPSQEKGLLEEYGINITEIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPGVG
KTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKREDIILFIDEIHEIVGAGSAGDG
NMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETIIILKGVQKKYEDYHHVKYTDAAIEA
AANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATREEDFEKAAYFRDQIAKYKEMQKK
KVTDQDTPIISEKTIEHIIEQKTNIPVGELKEKEQSQLIHLADDLKAHVIGQDEAVDKIAKAIRRNRVGLGTPNRPIGSF
LFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEVEK
AHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMNRFDGI
IEFKPLSKDNLLQIVELMLADVNKRLSSNNIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDYYLENPSEK
DLKAVMTNNGKIQIKSAKKTEKTEEIASEIEE

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=964618 NYE79_RS06930 WP_339293650.1 1375718..1377976(+) (clpE) [Streptococcus sp. FSL W8-0197]
ATGCTCTGTCAAAACTGTAAAATAAACGACTCAACAATTCATCTGTATACCAATATCAATGGACAGCAAAAACAAATTGA
TCTCTGTCAAAATTGCTATAAAATTATCAAAACAGATCCAAAAAATACCCTCTTTAAAGGAATGACTGACTTAAACAATC
GTGACTTTGATCCTTTCGGAGACTTTTTCAATGATTTGAACAATTTCAAACCTTCTTCTAATAACGTCCCTCCAACTCAA
TCTGGTGGAGGATATGGAGGAAACGGTGGTTATGGACCTCAAAACCGAGGCCCACTTCAAACACCTCCTAGTCAAGAAAA
AGGACTCCTAGAGGAATATGGTATCAATATTACTGAGATTGCTCGTCGGGGAGATATTGACCCTGTTATCGGTCGAGATG
AGGAGATTATCCGCGTTATCGAAATCCTCAACCGTCGAACCAAGAACAATCCTGTCCTTATCGGAGAACCAGGTGTCGGT
AAAACAGCCGTTGTCGAAGGTCTAGCTCAGAAGATTGTCGATGGCGATGTTCCCCATAAACTCCAAGGCAAGCAGGTCAT
CCGTCTGGATGTGGTCAGTCTAGTCCAAGGAACAGGGATTCGAGGCCAATTTGAAGAACGTATGCAAAAGCTCATGGAAG
AAATTCGCAAACGCGAGGACATCATCCTCTTTATCGATGAAATCCATGAAATTGTTGGTGCAGGATCTGCTGGCGATGGC
AATATGGATGCAGGAAATATCCTCAAACCAGCCCTTGCCCGTGGTGAATTACAAATGGTCGGAGCTACTACTCTCAATGA
ATACCGCATCATTGAAAAAGATGCTGCTCTAGAGCGCCGCATGCAGCCTGTCAAGGTAGATGAACCAACTGTCGAAGAAA
CCATTATCATCCTTAAAGGAGTTCAAAAGAAATACGAAGACTACCATCACGTCAAGTATACTGATGCTGCTATCGAAGCT
GCTGCAAATCTTTCCAATCGCTACATCCAAGACCGCTTCTTGCCAGACAAGGCTATTGACCTGTTGGATGAAGCTGGTTC
AAAGATGAATCTGACGCTGAACTTTGTTGATCCTAAAGTGATTGATCAGCGCTTGATTGAGGCTGAAAATCTCAAGGCTC
AAGCTACACGAGAGGAAGATTTTGAAAAGGCTGCTTATTTCCGCGATCAGATTGCCAAGTACAAGGAAATGCAGAAAAAA
AAGGTGACTGATCAGGATACTCCAATTATCAGCGAGAAAACCATTGAGCATATCATTGAGCAGAAAACCAATATTCCTGT
TGGAGAACTCAAAGAAAAAGAACAGTCTCAGCTTATCCATCTAGCAGACGACCTCAAGGCCCATGTCATTGGTCAAGATG
AAGCTGTCGATAAGATTGCCAAAGCCATCCGTCGTAATCGTGTTGGACTTGGAACTCCTAATCGGCCAATCGGAAGTTTC
CTCTTTGTCGGACCAACTGGTGTCGGTAAAACAGAACTTTCCAAACAACTAGCCATTGAGCTCTTTGGTTCTGCTGACAG
CATGATTCGCTTTGATATGAGTGAATACATGGAAAAACACAGTGTGGCTAAATTAGTCGGAGCCCCTCCAGGTTATGTTG
GCTACGATGAAGCGGGTCAGTTAACGGAAAAAGTTCGTCGCAATCCTTACTCACTCATCCTTCTCGATGAAGTTGAAAAA
GCCCATCCAGATGTGATGCACATGTTCCTTCAAGTCTTGGACGATGGTCGTTTGACAGATGGACAAGGACGAACAGTTAG
CTTTAAGGATGCTATCATTATCATGACCTCAAATGCTGGTACGGGTAAGGCCGAAGCCAGTGTTGGTTTTGGAGCTGCTC
GTGAAGGACGTACTAATTCTGTTCTCGGTGAACTCGGTAACTTCTTTAGTCCTGAGTTTATGAACCGTTTTGACGGCATC
ATCGAATTTAAACCTCTCAGCAAGGACAATCTTCTCCAAATCGTCGAACTCATGTTAGCGGATGTCAACAAACGCCTCTC
TAGCAACAATATCCACCTCGATGTGACAGACAAGGTCAAGGAAAAGTTGGTTGACTTAGGTTATGATCCAAAAATGGGGG
CGCGCCCACTCCGCCGTACCATTCAAGACCATATCGAGGATGCTATCACCGACTACTACCTTGAAAACCCAAGTGAAAAA
GACCTCAAGGCAGTTATGACAAACAATGGCAAAATTCAAATCAAATCTGCCAAAAAAACTGAGAAAACAGAAGAGATTGC
TTCTGAAATAGAAGAATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(475-638)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(646-720)

ATPase family associated with various cellular activities (AAA) (AAA)

(152-271)

AAA lid domain (AAA_lid_9)

(290-387)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

94.758

98.936

0.937
  clpE Streptococcus pneumoniae D39

94.758

98.936

0.937
  clpE Streptococcus pneumoniae R6

94.758

98.936

0.937
  clpE Streptococcus pneumoniae TIGR4

94.624

98.936

0.936
  clpE Streptococcus mutans UA159

83.024

100

0.832
  clpC Lactococcus lactis subsp. cremoris KW2

75.894

100

0.762
  clpC Bacillus subtilis subsp. subtilis str. 168

52.615

86.436

0.455
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.485

83.378

0.404
  clpC Streptococcus thermophilus LMD-9

46.91

83.91

0.394
  clpC Streptococcus thermophilus LMG 18311

46.677

84.043

0.392
  clpC Streptococcus mutans UA159

46.508

83.777

0.39
  clpC Streptococcus pneumoniae TIGR4

47.182

82.58

0.39
  clpC Streptococcus pneumoniae Rx1

47.182

82.58

0.39
  clpC Streptococcus pneumoniae D39

47.182

82.58

0.39

Multiple sequence alignment