Detailed information NTG0964211

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ACJEIC_RS09240
• Genome accession: NZ_CP174240
• Coordinates: 2052935..2054209 (-)
• Length: 424 a.a.
• NCBI ID: WP_011215825.1
• Uniprot ID: Q5WVJ1
• Organism: Legionella pneumophila strain SPF585
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2047935..2059209

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACJEIC_RS09230 (ACJEIC_09230)	-	2049844..2050122 (-)	279	WP_011214112.1	HU family DNA-binding protein	-
ACJEIC_RS09235 (ACJEIC_09235)	lon	2050251..2052701 (-)	2451	WP_011215824.1	endopeptidase La	-
ACJEIC_RS09240 (ACJEIC_09240)	clpX	2052935..2054209 (-)	1275	WP_011215825.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ACJEIC_RS09245 (ACJEIC_09245)	clpP	2054350..2054994 (-)	645	WP_011215826.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	-
ACJEIC_RS09250 (ACJEIC_09250)	tig	2054997..2056328 (-)	1332	WP_011215827.1	trigger factor	-
ACJEIC_RS09275 (ACJEIC_09275)	-	2057190..2058416 (+)	1227	WP_011215830.1	site-specific integrase	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46641.21 Da
• Isoelectric Point: 5.0727

>NTDB_id=964211 ACJEIC_RS09240 WP_011215825.1 2052935..2054209(-) (clpX) [Legionella pneumophila strain SPF585]
MSKSGNGNGDKVLYCSFCGKSQHEVKKLIAGPSVFVCDECVELCNDIIREETHETHEETEARLPTPKEISNFLDEYVIGQ
QHAKKVLSVAVYNHYKRLQHKSEDGVELGKSNILLIGPTGSGKTLLAQTLARILNVPFAMADATTLTEAGYVGEDVENII
QKLLQKCDYDVDKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTSN
ILFICGGAFAGLDKVIRERSDKSSIGFSAQLKSKKSSNDEVSKVLGQLESDDLIKYGLIPEFVGRLPVVTTLQELDEAAL
IDILTRPKNALTKQFQSLFKMEGSELEFRDEALIAIAKKALERKMGARGLRSILENILLDTMYDLPSLEGVNKVVIDESV
VNGLSKPILIYEQDEKKSASGSKD

Nucleotide

• Length: 1275 bp

>NTDB_id=964211 ACJEIC_RS09240 WP_011215825.1 2052935..2054209(-) (clpX) [Legionella pneumophila strain SPF585]
ATGAGTAAATCCGGTAACGGAAATGGAGATAAGGTCTTATATTGTTCTTTTTGTGGCAAGAGTCAACATGAGGTAAAAAA
ATTAATTGCTGGACCTTCTGTGTTTGTTTGTGATGAATGTGTAGAGCTATGTAATGATATTATTCGAGAAGAAACACATG
AAACTCATGAAGAAACTGAGGCACGTCTACCGACACCAAAAGAAATATCTAACTTTCTCGATGAATACGTAATAGGGCAA
CAACATGCCAAAAAGGTTTTATCAGTAGCAGTATATAATCACTATAAGAGATTACAGCATAAAAGCGAGGATGGTGTTGA
ACTTGGTAAAAGTAATATACTTCTTATAGGACCTACTGGCAGTGGTAAGACTCTTTTAGCTCAAACTCTGGCGCGGATTC
TTAATGTTCCTTTTGCCATGGCTGATGCCACGACCCTTACTGAAGCTGGATATGTTGGTGAAGACGTTGAAAATATCATC
CAGAAGTTATTACAGAAGTGCGACTATGATGTAGATAAGGCACAGCAAGGTATTGTCTATATCGACGAAATCGATAAGAT
TTCACGCAAATCAGATAATCCATCTATCACCAGAGATGTTTCAGGAGAAGGTGTTCAACAAGCTTTACTGAAATTAATTG
AAGGTACTGTTGCATCTGTTCCACCGCAAGGTGGGCGAAAGCATCCACAGCAAGAATTTTTGCAAGTAGATACGTCAAAT
ATTTTATTTATCTGTGGTGGCGCTTTTGCAGGTTTGGACAAAGTAATACGTGAGCGGAGCGATAAATCAAGCATAGGTTT
TTCTGCTCAATTAAAAAGCAAAAAAAGCAGTAATGATGAAGTTTCAAAAGTTTTAGGGCAATTGGAATCAGATGATTTAA
TTAAATATGGGTTAATTCCCGAGTTTGTTGGACGTTTGCCTGTTGTAACCACTTTACAGGAACTTGATGAAGCGGCATTG
ATTGATATATTAACGAGACCGAAGAATGCTTTAACAAAGCAGTTTCAATCACTTTTCAAAATGGAAGGTTCTGAACTCGA
GTTTAGAGACGAAGCTTTGATTGCTATTGCTAAAAAGGCCCTCGAAAGAAAAATGGGCGCAAGAGGTTTGCGATCAATAC
TTGAAAATATTCTTTTAGACACCATGTATGACTTACCTTCCTTGGAAGGCGTGAATAAGGTTGTTATTGATGAGAGTGTA
GTGAATGGGCTATCTAAACCGATTCTCATTTATGAACAGGATGAGAAAAAAAGTGCGTCTGGTAGTAAAGATTAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (315-387)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-308)

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

3D structure

• AlphaFold DB: Q5WVJ1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.658	96.462	0.575
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	54.926	95.755	0.526