Detailed information NTG0963778

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: NST22_RS18555
• Genome accession: NZ_CP150156
• Coordinates: 3572097..3573254 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus sp. PS237
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3567097..3578254

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NST22_RS18525 (NST22_18525)	-	3567350..3567769 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
NST22_RS18530 (NST22_18530)	comFC	3567843..3568565 (-)	723	WP_003227991.1	comF operon protein ComFC	Machinery gene
NST22_RS18535 (NST22_18535)	comFB	3568529..3568825 (-)	297	WP_003227989.1	late competence protein ComFB	-
NST22_RS18540 (NST22_18540)	comFA	3568885..3570276 (-)	1392	WP_003243962.1	ATP-dependent helicase ComFA	Machinery gene
NST22_RS18545 (NST22_18545)	-	3570382..3571227 (-)	846	WP_003244125.1	DegV family protein	-
NST22_RS18550 (NST22_18550)	degU	3571325..3572014 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
NST22_RS18555 (NST22_18555)	degS	3572097..3573254 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
NST22_RS18560 (NST22_18560)	-	3573471..3574124 (+)	654	WP_003227979.1	YigZ family protein	-
NST22_RS18565 (NST22_18565)	tagV	3574124..3575299 (+)	1176	WP_003244117.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
NST22_RS18570 (NST22_18570)	-	3575372..3576448 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
NST22_RS18575 (NST22_18575)	-	3576593..3577786 (-)	1194	WP_003243252.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=963778 NST22_RS18555 WP_003227983.1 3572097..3573254(-) (degS) [Bacillus sp. PS237]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=963778 NST22_RS18555 WP_003227983.1 3572097..3573254(-) (degS) [Bacillus sp. PS237]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTCCGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1