Detailed information NTG0963179

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: NSS86_RS08290
• Genome accession: NZ_CP150142
• Coordinates: 1649151..1650194 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus sp. FSL W8-0056
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1644151..1655194

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NSS86_RS08260 (NSS86_08260)	-	1644572..1645828 (-)	1257	WP_001795108.1	aminopeptidase	-
NSS86_RS08265 (NSS86_08265)	-	1645831..1646031 (-)	201	WP_000180460.1	DUF1128 family protein	-
NSS86_RS08270 (NSS86_08270)	-	1646178..1646642 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
NSS86_RS08275 (NSS86_08275)	-	1646649..1646924 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
NSS86_RS08280 (NSS86_08280)	-	1647202..1648419 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
NSS86_RS08285 (NSS86_08285)	vraR	1648532..1649161 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
NSS86_RS08290 (NSS86_08290)	vraS	1649151..1650194 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
NSS86_RS08295 (NSS86_08295)	liaF	1650191..1650892 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
NSS86_RS08300 (NSS86_08300)	-	1650907..1651293 (-)	387	WP_001110179.1	hypothetical protein	-
NSS86_RS08305 (NSS86_08305)	map	1651510..1652268 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
NSS86_RS08310 (NSS86_08310)	-	1652740..1653726 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
NSS86_RS08315 (NSS86_08315)	-	1654157..1654570 (-)	414	WP_001557448.1	hypothetical protein	-
NSS86_RS08320 (NSS86_08320)	-	1654599..1654709 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=963179 NSS86_RS08290 WP_001017131.1 1649151..1650194(-) (vraS) [Staphylococcus sp. FSL W8-0056]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=963179 NSS86_RS08290 WP_001017131.1 1649151..1650194(-) (vraS) [Staphylococcus sp. FSL W8-0056]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1