Detailed information NTG0962466

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ80_RS10390
• Genome accession: NZ_CP149974
• Coordinates: 2076473..2077516 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN125
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2071473..2082516

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ80_RS10360 (UXQ80_10360)	-	2071894..2073150 (-)	1257	WP_001795108.1	aminopeptidase	-
UXQ80_RS10365 (UXQ80_10365)	-	2073153..2073353 (-)	201	WP_000180460.1	DUF1128 family protein	-
UXQ80_RS10370 (UXQ80_10370)	-	2073500..2073964 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ80_RS10375 (UXQ80_10375)	-	2073971..2074246 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXQ80_RS10380 (UXQ80_10380)	-	2074524..2075741 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXQ80_RS10385 (UXQ80_10385)	vraR	2075854..2076483 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
UXQ80_RS10390 (UXQ80_10390)	vraS	2076473..2077516 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ80_RS10395 (UXQ80_10395)	liaF	2077513..2078214 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ80_RS10400 (UXQ80_10400)	-	2078229..2078615 (-)	387	WP_001110179.1	hypothetical protein	-
UXQ80_RS10405 (UXQ80_10405)	map	2078832..2079590 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXQ80_RS10410 (UXQ80_10410)	-	2080062..2081048 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
UXQ80_RS10415 (UXQ80_10415)	-	2081479..2081892 (-)	414	WP_001557448.1	hypothetical protein	-
UXQ80_RS10420 (UXQ80_10420)	-	2081921..2082031 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=962466 UXQ80_RS10390 WP_001017131.1 2076473..2077516(-) (vraS) [Staphylococcus aureus strain BSN125]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=962466 UXQ80_RS10390 WP_001017131.1 2076473..2077516(-) (vraS) [Staphylococcus aureus strain BSN125]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1