Detailed information NTG0961609

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXQ24_RS14270
• Genome accession: NZ_CP149807
• Coordinates: 2808138..2809025 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain BSN123
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2803138..2814025

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ24_RS14240 (UXQ24_14240)	-	2803157..2803249 (+)	93	WP_010956583.1	hypothetical protein	-
UXQ24_RS14245 (UXQ24_14245)	-	2803357..2803854 (-)	498	WP_001065268.1	glutathione peroxidase	-
UXQ24_RS14250 (UXQ24_14250)	-	2803864..2804124 (-)	261	WP_001789910.1	hypothetical protein	-
UXQ24_RS14255 (UXQ24_14255)	-	2804506..2804619 (-)	114	WP_001791776.1	hypothetical protein	-
UXQ24_RS14260 (UXQ24_14260)	-	2805278..2807278 (-)	2001	WP_000776751.1	ABC transporter permease	-
UXQ24_RS14265 (UXQ24_14265)	-	2807275..2808030 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXQ24_RS14270 (UXQ24_14270)	braS	2808138..2809025 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXQ24_RS14275 (UXQ24_14275)	braR	2809036..2809701 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXQ24_RS14280 (UXQ24_14280)	-	2809727..2809927 (-)	201	WP_000604728.1	hypothetical protein	-
UXQ24_RS14285 (UXQ24_14285)	-	2810125..2811549 (+)	1425	WP_000953744.1	alkaline phosphatase	-
UXQ24_RS14955	-	2811609..2811710 (-)	102	WP_000731972.1	SE2200 family small protein	-
UXQ24_RS14295 (UXQ24_14295)	-	2811832..2812287 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXQ24_RS14300 (UXQ24_14300)	-	2812532..2813293 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=961609 UXQ24_RS14270 WP_000143419.1 2808138..2809025(-) (braS) [Staphylococcus aureus strain BSN123]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=961609 UXQ24_RS14270 WP_000143419.1 2808138..2809025(-) (braS) [Staphylococcus aureus strain BSN123]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997