Detailed information
Bioinformatically predicted
Overview
| Name | recA | Type | Machinery gene |
| Locus tag | WIS49_RS06375 | Genome accession | NZ_CP149702 |
| Coordinates | 1353882..1354928 (+) | Length | 348 a.a. |
| NCBI ID | WP_003428218.1 | Uniprot ID | A0A031WFI0 |
| Organism | Clostridioides difficile strain Z1322PCD0025 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1321750..1402736 | 1353882..1354928 | within | 0 |
Gene organization within MGE regions
Location: 1321750..1402736
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| WIS49_RS06245 (WIS49_06245) | acd | 1321825..1323648 (+) | 1824 | WP_003438294.1 | N-acetylglucosaminidase | - |
| WIS49_RS06250 (WIS49_06250) | - | 1323863..1328161 (+) | 4299 | WP_003438301.1 | PolC-type DNA polymerase III | - |
| WIS49_RS06255 (WIS49_06255) | rimP | 1328365..1328826 (+) | 462 | WP_003438303.1 | ribosome maturation factor RimP | - |
| WIS49_RS06260 (WIS49_06260) | nusA | 1328856..1330010 (+) | 1155 | WP_003428238.1 | transcription termination factor NusA | - |
| WIS49_RS06265 (WIS49_06265) | - | 1330017..1330298 (+) | 282 | WP_003419469.1 | YlxR family protein | - |
| WIS49_RS06270 (WIS49_06270) | - | 1330288..1330599 (+) | 312 | WP_003419470.1 | ribosomal L7Ae/L30e/S12e/Gadd45 family protein | - |
| WIS49_RS06275 (WIS49_06275) | infB | 1330621..1332561 (+) | 1941 | WP_003438306.1 | translation initiation factor IF-2 | - |
| WIS49_RS06280 (WIS49_06280) | rbfA | 1332604..1332984 (+) | 381 | WP_003428234.1 | 30S ribosome-binding factor RbfA | - |
| WIS49_RS06285 (WIS49_06285) | - | 1332965..1333642 (+) | 678 | Protein_1143 | DHH family phosphoesterase | - |
| WIS49_RS06290 (WIS49_06290) | tnpB | 1334291..1335409 (+) | 1119 | WP_339072203.1 | IS200/IS605 family element RNA-guided endonuclease TnpB | - |
| WIS49_RS06295 (WIS49_06295) | - | 1335527..1335832 (+) | 306 | Protein_1145 | DHHA1 domain-containing protein | - |
| WIS49_RS06300 (WIS49_06300) | truB | 1335845..1336750 (+) | 906 | WP_003428232.1 | tRNA pseudouridine(55) synthase TruB | - |
| WIS49_RS06305 (WIS49_06305) | - | 1336881..1337810 (+) | 930 | WP_003438310.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| WIS49_RS06310 (WIS49_06310) | rpsO | 1337914..1338171 (+) | 258 | WP_003419491.1 | 30S ribosomal protein S15 | - |
| WIS49_RS06315 (WIS49_06315) | - | 1338411..1339256 (+) | 846 | WP_009889099.1 | DegV family protein | - |
| WIS49_RS06320 (WIS49_06320) | pnp | 1339381..1341492 (+) | 2112 | WP_003438316.1 | polyribonucleotide nucleotidyltransferase | - |
| WIS49_RS06325 (WIS49_06325) | - | 1341758..1342501 (+) | 744 | WP_003438319.1 | polysaccharide deacetylase family protein | - |
| WIS49_RS06330 (WIS49_06330) | - | 1342659..1343906 (+) | 1248 | WP_003438321.1 | pitrilysin family protein | - |
| WIS49_RS06335 (WIS49_06335) | - | 1343941..1344186 (+) | 246 | WP_003419503.1 | YlmC/YmxH family sporulation protein | - |
| WIS49_RS06340 (WIS49_06340) | dapG | 1344196..1345419 (+) | 1224 | WP_003438324.1 | aspartate kinase | - |
| WIS49_RS06345 (WIS49_06345) | tnpB | 1346208..1347326 (+) | 1119 | WP_339072209.1 | IS200/IS605 family element RNA-guided endonuclease TnpB | - |
| WIS49_RS06350 (WIS49_06350) | - | 1347513..1348142 (+) | 630 | WP_021363436.1 | ATP-dependent Clp protease proteolytic subunit | - |
| WIS49_RS06355 (WIS49_06355) | - | 1348265..1350676 (+) | 2412 | WP_003438328.1 | DNA translocase FtsK | - |
| WIS49_RS06360 (WIS49_06360) | mnmH | 1350679..1351737 (+) | 1059 | WP_003433322.1 | tRNA 2-selenouridine(34) synthase MnmH | - |
| WIS49_RS06365 (WIS49_06365) | rimO | 1351731..1353065 (+) | 1335 | WP_159376147.1 | 30S ribosomal protein S12 methylthiotransferase RimO | - |
| WIS49_RS06370 (WIS49_06370) | pgsA | 1353052..1353594 (+) | 543 | WP_009889106.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| WIS49_RS06375 (WIS49_06375) | recA | 1353882..1354928 (+) | 1047 | WP_003428218.1 | recombinase RecA | Machinery gene |
| WIS49_RS06380 (WIS49_06380) | rny | 1355104..1356645 (+) | 1542 | WP_003428216.1 | ribonuclease Y | - |
| WIS49_RS06385 (WIS49_06385) | - | 1356959..1359295 (+) | 2337 | WP_003438341.1 | diguanylate cyclase | - |
| WIS49_RS06390 (WIS49_06390) | - | 1359677..1361458 (+) | 1782 | WP_003438344.1 | UvrD-helicase domain-containing protein | - |
| WIS49_RS06395 (WIS49_06395) | lepB | 1361540..1362070 (-) | 531 | WP_009902411.1 | signal peptidase I | - |
| WIS49_RS06400 (WIS49_06400) | - | 1362110..1362934 (-) | 825 | WP_003438350.1 | undecaprenyl-diphosphate phosphatase | - |
| WIS49_RS06405 (WIS49_06405) | - | 1363191..1364099 (+) | 909 | WP_009889110.1 | tyrosine-type recombinase/integrase | - |
| WIS49_RS06410 (WIS49_06410) | purB | 1364243..1365688 (+) | 1446 | WP_003438353.1 | adenylosuccinate lyase | - |
| WIS49_RS06415 (WIS49_06415) | - | 1365999..1366451 (+) | 453 | WP_003419561.1 | MarR family transcriptional regulator | - |
| WIS49_RS06420 (WIS49_06420) | - | 1366786..1367982 (-) | 1197 | WP_003438357.1 | pyridoxal phosphate-dependent aminotransferase | - |
| WIS49_RS06425 (WIS49_06425) | galT | 1368367..1369317 (+) | 951 | WP_070538166.1 | galactose-1-phosphate uridylyltransferase | - |
| WIS49_RS06430 (WIS49_06430) | - | 1369478..1370230 (+) | 753 | WP_003438367.1 | exodeoxyribonuclease III | - |
| WIS49_RS06435 (WIS49_06435) | - | 1370322..1371098 (-) | 777 | WP_009896237.1 | 3'-5' exonuclease | - |
| WIS49_RS06440 (WIS49_06440) | - | 1371413..1373311 (+) | 1899 | WP_070538168.1 | glutamine synthetase | - |
| WIS49_RS06445 (WIS49_06445) | - | 1373439..1374560 (-) | 1122 | WP_003428201.1 | glycosyltransferase | - |
| WIS49_RS06450 (WIS49_06450) | - | 1374759..1375091 (+) | 333 | WP_009889116.1 | PadR family transcriptional regulator | - |
| WIS49_RS06455 (WIS49_06455) | - | 1375078..1376136 (+) | 1059 | WP_003438377.1 | DUF1700 domain-containing protein | - |
| WIS49_RS06460 (WIS49_06460) | - | 1376129..1377199 (+) | 1071 | WP_011861183.1 | DUF4097 family beta strand repeat-containing protein | - |
| WIS49_RS06465 (WIS49_06465) | - | 1377301..1377837 (+) | 537 | WP_075052540.1 | hypothetical protein | - |
| WIS49_RS06470 (WIS49_06470) | - | 1377953..1378660 (+) | 708 | WP_016729592.1 | lantibiotic protection ABC transporter ATP-binding protein | - |
| WIS49_RS06475 (WIS49_06475) | - | 1378662..1379378 (+) | 717 | WP_016729591.1 | lantibiotic immunity ABC transporter MutE/EpiE family permease subunit | - |
| WIS49_RS06480 (WIS49_06480) | - | 1379380..1380138 (+) | 759 | WP_159376148.1 | lantibiotic immunity ABC transporter MutG family permease subunit | - |
| WIS49_RS06485 (WIS49_06485) | - | 1380273..1381661 (+) | 1389 | WP_159376149.1 | two-component system sensor histidine kinase | - |
| WIS49_RS06490 (WIS49_06490) | - | 1381737..1382558 (-) | 822 | WP_003428191.1 | pyridoxamine kinase | - |
| WIS49_RS06495 (WIS49_06495) | - | 1382809..1383963 (+) | 1155 | WP_009892989.1 | amidase domain-containing protein | - |
| WIS49_RS06500 (WIS49_06500) | - | 1384146..1384346 (+) | 201 | WP_003419624.1 | cold-shock protein | - |
| WIS49_RS06505 (WIS49_06505) | - | 1384767..1385195 (+) | 429 | WP_009889129.1 | CBS domain-containing protein | - |
| WIS49_RS06510 (WIS49_06510) | - | 1385338..1386093 (-) | 756 | WP_009889131.1 | peptidylprolyl isomerase | - |
| WIS49_RS06515 (WIS49_06515) | - | 1386794..1387300 (-) | 507 | WP_011861186.1 | hypothetical protein | - |
| WIS49_RS06520 (WIS49_06520) | - | 1387382..1387702 (-) | 321 | WP_003428185.1 | XRE family transcriptional regulator | - |
| WIS49_RS06525 (WIS49_06525) | - | 1387871..1388068 (+) | 198 | WP_003419641.1 | helix-turn-helix transcriptional regulator | - |
| WIS49_RS06530 (WIS49_06530) | - | 1388172..1388612 (+) | 441 | WP_003428183.1 | hypothetical protein | - |
| WIS49_RS06535 (WIS49_06535) | - | 1388861..1389304 (+) | 444 | WP_159376150.1 | DUF6838 family protein | - |
| WIS49_RS06540 (WIS49_06540) | - | 1389309..1390373 (+) | 1065 | WP_003438414.1 | phage tail sheath subtilisin-like domain-containing protein | - |
| WIS49_RS06545 (WIS49_06545) | - | 1390387..1390815 (+) | 429 | WP_003419646.1 | phage tail tube protein | - |
| WIS49_RS06550 (WIS49_06550) | - | 1390941..1391387 (+) | 447 | WP_003419647.1 | phage portal protein | - |
| WIS49_RS06555 (WIS49_06555) | - | 1391581..1394034 (+) | 2454 | WP_159376151.1 | hypothetical protein | - |
| WIS49_RS06560 (WIS49_06560) | - | 1394034..1394456 (+) | 423 | WP_003428168.1 | phage baseplate protein | - |
| WIS49_RS06565 (WIS49_06565) | - | 1394738..1396267 (+) | 1530 | WP_009902435.1 | NlpC/P60 family protein | - |
| WIS49_RS06570 (WIS49_06570) | - | 1396283..1396609 (+) | 327 | WP_003438447.1 | DUF2577 domain-containing protein | - |
| WIS49_RS06575 (WIS49_06575) | - | 1396609..1397037 (+) | 429 | WP_003438449.1 | DUF2634 domain-containing protein | - |
| WIS49_RS06580 (WIS49_06580) | - | 1397030..1398082 (+) | 1053 | WP_003438450.1 | baseplate J/gp47 family protein | - |
| WIS49_RS06585 (WIS49_06585) | - | 1398079..1398777 (+) | 699 | WP_003428156.1 | putative phage tail protein | - |
| WIS49_RS06590 (WIS49_06590) | - | 1398778..1399761 (+) | 984 | WP_021366456.1 | phage tail protein | - |
Sequence
Protein
Download Length: 348 a.a. Molecular weight: 37377.68 Da Isoelectric Point: 4.8236
>NTDB_id=960830 WIS49_RS06375 WP_003428218.1 1353882..1354928(+) (recA) [Clostridioides difficile strain Z1322PCD0025]
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEI
DEKVRAFYNLNEEHEESGTSVSKEIVEE
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEI
DEKVRAFYNLNEEHEESGTSVSKEIVEE
Nucleotide
Download Length: 1047 bp
>NTDB_id=960830 WIS49_RS06375 WP_003428218.1 1353882..1354928(+) (recA) [Clostridioides difficile strain Z1322PCD0025]
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGACATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAGACTACTGTTGCGCTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACACGCACTTGACCCAGTATATGCAAAAGC
TTTGGGTGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGATTCTCATGTAGGTTTACAAGCTAGACTTATGTCACAAGCACTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCAGAAACTACTACTGGAGGAC
GTGCACTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGATACAATAAAACAAGGTGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTTGTTAAAAACAAAGTAGCACCACCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGGATTTCAAAAATTGGAGACCTTTTAGATATAGCTGCTGATGTAGATATAGTTAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAAGATAATTTAGATTTAACTACTGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAATCAGGTACTTCAGTATCAAAAGAAATTGTAGA
AGAATAA
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGACATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAGACTACTGTTGCGCTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACACGCACTTGACCCAGTATATGCAAAAGC
TTTGGGTGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGATTCTCATGTAGGTTTACAAGCTAGACTTATGTCACAAGCACTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCAGAAACTACTACTGGAGGAC
GTGCACTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGATACAATAAAACAAGGTGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTTGTTAAAAACAAAGTAGCACCACCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGGATTTCAAAAATTGGAGACCTTTTAGATATAGCTGCTGATGTAGATATAGTTAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAAGATAATTTAGATTTAACTACTGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAATCAGGTACTTCAGTATCAAAAGAAATTGTAGA
AGAATAA
Similar proteins
Only experimentally validated proteins are listed.