Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   WKI52_RS11400 Genome accession   NZ_CP149646
Coordinates   2201281..2201937 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain MJ06     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2196281..2206937
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WKI52_RS11375 (WKI52_11375) oppF 2196820..2197737 (+) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -
  WKI52_RS11380 (WKI52_11380) - 2197844..2199022 (+) 1179 WP_079979752.1 putative glycoside hydrolase -
  WKI52_RS11385 (WKI52_11385) - 2199140..2199718 (+) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  WKI52_RS11390 (WKI52_11390) spx 2199897..2200292 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  WKI52_RS11395 (WKI52_11395) - 2200349..2201005 (-) 657 WP_014417421.1 TerC family protein -
  WKI52_RS11400 (WKI52_11400) mecA 2201281..2201937 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  WKI52_RS11405 (WKI52_11405) - 2202088..2203248 (+) 1161 WP_071391994.1 competence protein CoiA family protein -
  WKI52_RS11410 (WKI52_11410) pepF 2203476..2205305 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  WKI52_RS11415 (WKI52_11415) - 2205343..2205510 (-) 168 WP_003155026.1 hypothetical protein -
  WKI52_RS11420 (WKI52_11420) spxH 2205796..2206698 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=960213 WKI52_RS11400 WP_003155032.1 2201281..2201937(+) (mecA) [Bacillus velezensis strain MJ06]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=960213 WKI52_RS11400 WP_003155032.1 2201281..2201937(+) (mecA) [Bacillus velezensis strain MJ06]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCTTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895