Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   WJ062_RS05940 Genome accession   NZ_CP149486
Coordinates   1209722..1210759 (-) Length   345 a.a.
NCBI ID   WP_012560824.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain EMM113     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1204722..1215759
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WJ062_RS05920 (WJ062_05890) - 1205472..1206098 (+) 627 WP_002983834.1 A24 family peptidase -
  WJ062_RS05925 (WJ062_05895) rlmN 1206180..1207259 (-) 1080 WP_002992788.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  WJ062_RS05930 (WJ062_05900) - 1207263..1207883 (-) 621 WP_032464468.1 YutD family protein -
  WJ062_RS05935 (WJ062_05905) - 1208331..1209308 (-) 978 WP_136117105.1 LacI family DNA-binding transcriptional regulator -
  WJ062_RS05940 (WJ062_05910) sepM 1209722..1210759 (-) 1038 WP_012560824.1 SepM family pheromone-processing serine protease Regulator
  WJ062_RS05945 (WJ062_05915) coaD 1210746..1211237 (-) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  WJ062_RS05950 (WJ062_05920) rsmD 1211227..1211766 (-) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  WJ062_RS05955 (WJ062_05925) asnA 1211889..1212881 (-) 993 WP_136021588.1 aspartate--ammonia ligase -
  WJ062_RS05960 (WJ062_05930) arcC 1213194..1214144 (-) 951 WP_076634519.1 carbamate kinase -
  WJ062_RS05965 (WJ062_05935) - 1214164..1215495 (-) 1332 WP_136021589.1 dipeptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37541.20 Da        Isoelectric Point: 9.5788

>NTDB_id=959442 WJ062_RS05940 WP_012560824.1 1209722..1210759(-) (sepM) [Streptococcus pyogenes strain EMM113]
MKRLNKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPITTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=959442 WJ062_RS05940 WP_012560824.1 1209722..1210759(-) (sepM) [Streptococcus pyogenes strain EMM113]
ATGAAAAGACTTAACAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTATTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.696

100

0.687