Detailed information NTG0959274

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXR27_RS13445
• Genome accession: NZ_CP149461
• Coordinates: 2681901..2682788 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain BSN78
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2676901..2687788

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR27_RS13415 (UXR27_13415)	-	2676920..2677012 (+)	93	WP_010956583.1	hypothetical protein	-
UXR27_RS13420 (UXR27_13420)	-	2677120..2677617 (-)	498	WP_001065268.1	glutathione peroxidase	-
UXR27_RS13425 (UXR27_13425)	-	2677627..2677887 (-)	261	WP_001791974.1	hypothetical protein	-
UXR27_RS13430 (UXR27_13430)	-	2678269..2678382 (-)	114	Protein_2597	hypothetical protein	-
UXR27_RS13435 (UXR27_13435)	-	2679041..2681041 (-)	2001	WP_000776751.1	ABC transporter permease	-
UXR27_RS13440 (UXR27_13440)	-	2681038..2681793 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXR27_RS13445 (UXR27_13445)	braS	2681901..2682788 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXR27_RS13450 (UXR27_13450)	braR	2682799..2683464 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXR27_RS13455 (UXR27_13455)	-	2683490..2683690 (-)	201	WP_000604730.1	hypothetical protein	-
UXR27_RS13460 (UXR27_13460)	-	2683888..2685312 (+)	1425	WP_000953755.1	alkaline phosphatase	-
UXR27_RS14060	-	2685372..2685473 (-)	102	WP_000731976.1	SE2200 family small protein	-
UXR27_RS13470 (UXR27_13470)	-	2685595..2686050 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXR27_RS13475 (UXR27_13475)	-	2686295..2687056 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=959274 UXR27_RS13445 WP_000143425.1 2681901..2682788(-) (braS) [Staphylococcus aureus strain BSN78]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=959274 UXR27_RS13445 WP_000143425.1 2681901..2682788(-) (braS) [Staphylococcus aureus strain BSN78]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1