Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   UXR27_RS02290 Genome accession   NZ_CP149461
Coordinates   467222..467896 (+) Length   224 a.a.
NCBI ID   WP_000866106.1    Uniprot ID   -
Organism   Staphylococcus aureus strain BSN78     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 455297..474651 467222..467896 within 0


Gene organization within MGE regions


Location: 455297..474651
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UXR27_RS02230 (UXR27_02230) - 455297..455971 (-) 675 WP_053027919.1 IS6-like element IS257 family transposase -
  UXR27_RS02235 (UXR27_02235) - 456037..456633 (+) 597 WP_000275959.1 gamma-glutamyltransferase -
  UXR27_RS02240 (UXR27_02240) - 456882..457739 (+) 858 WP_000162894.1 YitT family protein -
  UXR27_RS02245 (UXR27_02245) - 457889..458500 (-) 612 WP_000635275.1 recombinase family protein -
  UXR27_RS02250 (UXR27_02250) - 458986..459885 (-) 900 WP_000196697.1 Mph(C) family macrolide 2'-phosphotransferase -
  UXR27_RS02255 (UXR27_02255) msr(A) 459984..461450 (-) 1467 WP_000438874.1 ABC-F type ribosomal protection protein Msr(A) -
  UXR27_RS02260 (UXR27_02260) - 461924..462598 (+) 675 WP_001105960.1 IS6 family transposase -
  UXR27_RS02265 (UXR27_02265) - 462892..463065 (-) 174 WP_000044738.1 hypothetical protein -
  UXR27_RS02270 (UXR27_02270) - 463109..463729 (-) 621 WP_000941203.1 LysE/ArgO family amino acid transporter -
  UXR27_RS02275 (UXR27_02275) - 463734..464705 (-) 972 WP_000053810.1 fatty acid desaturase family protein -
  UXR27_RS02280 (UXR27_02280) - 464804..466216 (+) 1413 WP_000526300.1 PLP-dependent aminotransferase family protein -
  UXR27_RS02285 (UXR27_02285) - 466408..467082 (+) 675 WP_001105960.1 IS6 family transposase -
  UXR27_RS02290 (UXR27_02290) braR 467222..467896 (+) 675 WP_000866106.1 response regulator transcription factor Regulator
  UXR27_RS02295 (UXR27_02295) - 467893..468774 (+) 882 Protein_455 sensor histidine kinase -
  UXR27_RS02300 (UXR27_02300) - 468890..469819 (+) 930 WP_078367733.1 ABC transporter ATP-binding protein -
  UXR27_RS02305 (UXR27_02305) - 469812..470549 (+) 738 WP_000369394.1 ABC transporter permease -
  UXR27_RS02310 (UXR27_02310) - 470563..470751 (+) 189 Protein_458 undecaprenyl-diphosphate phosphatase -
  UXR27_RS02315 (UXR27_02315) - 470796..471470 (+) 675 WP_001105960.1 IS6 family transposase -
  UXR27_RS02320 (UXR27_02320) - 471611..472246 (+) 636 Protein_460 aminoglycoside 6-adenylyltransferase -
  UXR27_RS02325 (UXR27_02325) sat4 472243..472785 (+) 543 WP_000627290.1 streptothricin N-acetyltransferase Sat4 -
  UXR27_RS02330 (UXR27_02330) aph(3')-IIIa 472878..473672 (+) 795 WP_001096887.1 aminoglycoside O-phosphotransferase APH(3')-IIIa -
  UXR27_RS02335 (UXR27_02335) - 473977..474651 (-) 675 WP_001105987.1 IS6-like element IS257 family transposase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25839.93 Da        Isoelectric Point: 4.9884

>NTDB_id=959236 UXR27_RS02290 WP_000866106.1 467222..467896(+) (braR) [Staphylococcus aureus strain BSN78]
MKVLIVEDDLVIGKMLAEELKKWQLEPILIEGFNHVMDAFNTNAPELVLLDINLPAFNGYHWCQEIRKVSTVPIIFISSR
NDSMDQVMAMQMGADDFIEKPFNMTVTITKIQALLRRTYDFTTQVNNLTVDDCELLLDAAKLKFNEETIDLTHTELQIMH
SLFQNKGKFVSRNALIEKCWESEHFIDDNTLAVNITRLRKKLQKLGLTDFIETKKNVGYRVGDV

Nucleotide


Download         Length: 675 bp        

>NTDB_id=959236 UXR27_RS02290 WP_000866106.1 467222..467896(+) (braR) [Staphylococcus aureus strain BSN78]
ATGAAAGTATTAATCGTAGAGGATGACTTAGTTATCGGGAAGATGCTTGCTGAAGAGCTCAAGAAGTGGCAGCTAGAACC
GATCTTAATAGAAGGTTTCAATCATGTAATGGATGCCTTCAACACGAATGCACCGGAACTTGTGTTACTCGATATTAATT
TACCTGCCTTCAATGGTTATCACTGGTGTCAGGAGATTCGTAAAGTTTCTACTGTACCGATTATATTTATTAGTTCGCGT
AACGACAGTATGGATCAAGTAATGGCGATGCAGATGGGTGCGGATGATTTCATTGAGAAGCCATTTAATATGACTGTTAC
AATTACTAAGATTCAAGCACTATTACGCCGCACGTATGATTTCACCACTCAAGTTAATAATTTAACAGTAGATGATTGCG
AGTTACTACTTGATGCAGCAAAGCTTAAATTTAATGAAGAAACCATAGACCTGACACACACTGAATTGCAAATCATGCAT
AGCTTATTCCAGAACAAGGGCAAATTCGTCAGTCGTAATGCGTTAATCGAAAAATGCTGGGAATCAGAACACTTCATTGA
TGACAATACGCTTGCTGTCAACATTACACGTTTACGCAAAAAGCTACAAAAACTAGGACTTACAGATTTTATCGAAACGA
AGAAAAATGTCGGATATCGTGTAGGTGACGTATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

66.516

98.661

0.656