Detailed information    

insolico Bioinformatically predicted

Overview


Name   brsR   Type   Regulator
Locus tag   AABA19_RS00905 Genome accession   NZ_AP028609
Coordinates   169578..170018 (-) Length   146 a.a.
NCBI ID   WP_000861956.1    Uniprot ID   A0A0H2UNA2
Organism   Streptococcus pneumoniae strain Sep4     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 164578..175018
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA19_RS00880 (TKY121806_01640) - 164839..166125 (+) 1287 WP_000278868.1 response regulator transcription factor -
  AABA19_RS00885 (TKY121806_01650) - 166177..166710 (+) 534 WP_000729032.1 ABC transporter permease -
  AABA19_RS00890 (TKY121806_01660) nrdI 166788..167258 (+) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  AABA19_RS00895 (TKY121806_01670) - 167551..168813 (-) 1263 WP_000075790.1 NRAMP family divalent metal transporter -
  AABA19_RS00900 (TKY121806_01680) - 169123..169581 (-) 459 WP_000745054.1 DUF3021 domain-containing protein -
  AABA19_RS00905 (TKY121806_01690) brsR 169578..170018 (-) 441 WP_000861956.1 LytTR family DNA-binding domain-containing protein Regulator
  AABA19_RS00910 - 170106..170231 (-) 126 WP_001813544.1 hypothetical protein -
  AABA19_RS00915 (TKY121806_01700) hexB 170374..172323 (+) 1950 WP_061465146.1 DNA mismatch repair endonuclease MutL Machinery gene
  AABA19_RS00920 (TKY121806_01710) ribE 172648..173115 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  AABA19_RS00925 (TKY121806_01720) - 173116..174321 (-) 1206 WP_001818099.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  AABA19_RS00930 (TKY121806_01730) ribE 174341..174976 (-) 636 WP_000493841.1 riboflavin synthase -

Sequence


Protein


Download         Length: 146 a.a.        Molecular weight: 17183.84 Da        Isoelectric Point: 5.3783

>NTDB_id=95917 AABA19_RS00905 WP_000861956.1 169578..170018(-) (brsR) [Streptococcus pneumoniae strain Sep4]
MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=95917 AABA19_RS00905 WP_000861956.1 169578..170018(-) (brsR) [Streptococcus pneumoniae strain Sep4]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAAGAAACCGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains


Predicted by InterProScan.

(50-144)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0H2UNA2

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363


Multiple sequence alignment