Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   LLI816_RS08780 Genome accession   NZ_CP149095
Coordinates   1740567..1742042 (-) Length   491 a.a.
NCBI ID   WP_063283479.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain I8-16     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1735567..1747042
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLI816_RS08765 (LLI816_08765) murD 1736827..1738179 (-) 1353 WP_063283478.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  LLI816_RS08770 (LLI816_08770) - 1738670..1739011 (-) 342 WP_010906046.1 P-II family nitrogen regulator -
  LLI816_RS08775 (LLI816_08775) - 1739143..1740384 (-) 1242 WP_003130753.1 ammonium transporter -
  LLI816_RS08780 (LLI816_08780) covS 1740567..1742042 (-) 1476 WP_063283479.1 HAMP domain-containing histidine kinase Regulator
  LLI816_RS08785 (LLI816_08785) covR 1742050..1742742 (-) 693 WP_003130756.1 response regulator transcription factor Regulator
  LLI816_RS08790 (LLI816_08790) - 1742898..1743428 (-) 531 WP_003130758.1 DUF177 domain-containing protein -
  LLI816_RS08795 (LLI816_08795) - 1743559..1743804 (-) 246 WP_003130760.1 type B 50S ribosomal protein L31 -
  LLI816_RS08800 (LLI816_08800) - 1743960..1744424 (-) 465 WP_003130761.1 hypothetical protein -
  LLI816_RS08805 (LLI816_08805) - 1744506..1744868 (-) 363 WP_010906050.1 TIGR02328 family protein -
  LLI816_RS08810 (LLI816_08810) - 1745353..1745883 (-) 531 WP_063283480.1 CHAP domain-containing protein -
  LLI816_RS08815 (LLI816_08815) - 1745944..1746780 (-) 837 WP_003130766.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 491 a.a.        Molecular weight: 56146.01 Da        Isoelectric Point: 4.8253

>NTDB_id=956613 LLI816_RS08780 WP_063283479.1 1740567..1742042(-) (covS) [Lactococcus lactis subsp. lactis strain I8-16]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQQLLTRSMDSVEEVLEKADAPL
NSSNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHTFGFQNQANNEMKEIRGENPGYLVQRKII
SKSTGQVVGYLQAFYDTTTYHRISNLLLIVLLILEIVALIVAQLIGYFMANYFMKPLEKLYQGMQEMANDPTNDFEPIEI
QSGDEIEELAHVYNDMMLKMKANLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVCNRALKNFQLLHDDFEIVLDNRLIYPTHARISENHFEQGLRILLDNAAKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGISEEDINHLFERFFRADKARNREIGGTGLGLSILARLAENYQGEIEVNSELGLG
STFTLKFPKIK

Nucleotide


Download         Length: 1476 bp        

>NTDB_id=956613 LLI816_RS08780 WP_063283479.1 1740567..1742042(-) (covS) [Lactococcus lactis subsp. lactis strain I8-16]
ATGAAAAAACTATTTACTTTCAATAAGAAAAAAGAGACGGTAGAGGAAAGTTCGGCTAAGCGGTCTATCATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTTTGTTTGCTACTTTGACTTATCAATTGACAATCAGTTCTT
TTATTAAAGAAGAACAACAATTATTAACTCGCTCTATGGATAGTGTTGAGGAAGTCTTAGAAAAAGCAGATGCTCCTTTG
AATTCATCGAATTTGAACACATATATTGAAGCGACATCAAAGATTCAAAATGGTGAGTCTGAAGGAATGAGTTTGGGTAG
TATCATTGGGACACGGAAAGCATTTTATATTTATGACTTAAATCATAAATTATTGTATTCAACGAATCGACATACTTTTG
GTTTTCAGAATCAGGCTAATAATGAAATGAAAGAGATTCGGGGAGAAAATCCAGGTTATTTAGTTCAGAGAAAAATTATT
TCTAAGTCAACAGGACAAGTTGTGGGATACTTACAGGCTTTTTATGATACGACGACTTATCATCGAATTTCTAATCTTCT
TTTGATTGTCTTGTTAATTTTAGAAATTGTTGCCTTGATTGTCGCTCAGTTGATTGGTTATTTCATGGCTAATTACTTTA
TGAAACCATTGGAAAAACTTTATCAGGGCATGCAAGAAATGGCAAATGATCCAACAAATGATTTTGAACCGATTGAAATT
CAAAGTGGAGATGAAATCGAAGAGTTGGCTCATGTTTACAATGATATGATGTTGAAGATGAAGGCAAATCTTGAACAGCA
AAATCGCTTTGTTTCTGATGTTTCTCATGAATTAAGAACACCTTTAGCTGTCTTGGATGGACATATTAACTTGTTGAATC
GATGGGGGAAAAATGATCCAGAAGTATTAGATGAATCTTTGCAGGCAAGTTTAGATGAAGTTGATCGAATGAAGAAAATG
CTTGAGGAGATGTTGGCTCTTGCTCGCCTTGAAAATGTTGACTTATCAAGTGAAGAACTGGATTGTGATGTTGGAAAAGT
TTGTAATCGGGCCCTTAAGAATTTTCAGCTTTTGCATGATGATTTTGAAATAGTGCTTGATAACCGGCTTATTTATCCCA
CTCATGCGCGAATTTCAGAAAATCATTTTGAACAAGGGTTACGAATTCTGTTAGATAATGCTGCTAAATACTCTCCTGAT
GATCGTAAAGAAATCGTGATTACTGTTTCTGAGGATGAACAGTTTGTGATTACGAGTGTATCTGACAAAGGAATTGGAAT
TTCAGAAGAAGATATTAATCATCTTTTTGAGCGTTTCTTTAGAGCGGACAAGGCTCGCAATCGAGAAATTGGTGGAACTG
GTTTAGGTTTATCAATTTTAGCTCGATTGGCAGAAAATTATCAAGGGGAAATTGAGGTAAATTCAGAACTGGGTCTTGGT
TCAACTTTTACACTAAAATTCCCGAAAATAAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-489)

HAMP domain (HAMP)

(208-258)

ArlS sensor domain (ArlS_N)

(54-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

99.796

100

0.998