Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   UXQ75_RS09970 Genome accession   NZ_CP148992
Coordinates   2025198..2025872 (-) Length   224 a.a.
NCBI ID   WP_000866106.1    Uniprot ID   -
Organism   Staphylococcus aureus strain BSN76     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 2010774..2030452 2025198..2025872 within 0


Gene organization within MGE regions


Location: 2010774..2030452
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UXQ75_RS09880 (UXQ75_09880) blaZ 2010774..2011619 (+) 846 WP_000733623.1 penicillin-hydrolyzing class A beta-lactamase BlaZ -
  UXQ75_RS09885 (UXQ75_09885) - 2011660..2012101 (-) 442 Protein_1909 transposase -
  UXQ75_RS09890 (UXQ75_09890) - 2012160..2012834 (-) 675 WP_001105987.1 IS6-like element IS257 family transposase -
  UXQ75_RS09895 (UXQ75_09895) - 2012884..2013285 (+) 402 Protein_1911 replication initiation protein -
  UXQ75_RS09900 (UXQ75_09900) tet(K) 2013447..2014826 (+) 1380 WP_000492283.1 tetracycline efflux MFS transporter Tet(K) -
  UXQ75_RS09905 (UXQ75_09905) mobV 2015013..2016212 (+) 1200 WP_001829561.1 MobV family relaxase -
  UXQ75_RS09910 (UXQ75_09910) - 2016242..2016916 (+) 675 WP_001105960.1 IS6 family transposase -
  UXQ75_RS09915 (UXQ75_09915) - 2017424..2018083 (-) 660 WP_000802831.1 dihydrofolate reductase family protein -
  UXQ75_RS13865 - 2018194..2018939 (-) 746 Protein_1916 helix-turn-helix transcriptional regulator -
  UXQ75_RS13870 - 2019033..2019146 (-) 114 Protein_1917 transcriptional regulator -
  UXQ75_RS09930 (UXQ75_09930) aph(3')-IIIa 2019422..2020216 (-) 795 WP_001096887.1 aminoglycoside O-phosphotransferase APH(3')-IIIa -
  UXQ75_RS09935 (UXQ75_09935) sat4 2020309..2020851 (-) 543 WP_000627290.1 streptothricin N-acetyltransferase Sat4 -
  UXQ75_RS09940 (UXQ75_09940) - 2020848..2021483 (-) 636 Protein_1920 aminoglycoside 6-adenylyltransferase -
  UXQ75_RS09945 (UXQ75_09945) - 2021624..2022298 (-) 675 WP_001105960.1 IS6 family transposase -
  UXQ75_RS09950 (UXQ75_09950) - 2022343..2022531 (-) 189 Protein_1922 undecaprenyl-diphosphate phosphatase -
  UXQ75_RS09955 (UXQ75_09955) - 2022545..2023282 (-) 738 WP_000369394.1 ABC transporter permease -
  UXQ75_RS09960 (UXQ75_09960) - 2023275..2024204 (-) 930 WP_000793446.1 ABC transporter ATP-binding protein -
  UXQ75_RS09965 (UXQ75_09965) - 2024320..2025201 (-) 882 Protein_1925 sensor histidine kinase -
  UXQ75_RS09970 (UXQ75_09970) braR 2025198..2025872 (-) 675 WP_000866106.1 response regulator transcription factor Regulator
  UXQ75_RS09975 (UXQ75_09975) - 2026012..2026686 (-) 675 WP_001105960.1 IS6 family transposase -
  UXQ75_RS09980 (UXQ75_09980) msr(A) 2027160..2028626 (+) 1467 WP_000438873.1 ABC-F type ribosomal protection protein Msr(A) -
  UXQ75_RS09985 (UXQ75_09985) - 2028688..2029362 (-) 675 WP_001105987.1 IS6-like element IS257 family transposase -
  UXQ75_RS09990 (UXQ75_09990) - 2029412..2030452 (-) 1041 Protein_1930 IS1182 family transposase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25839.93 Da        Isoelectric Point: 4.9884

>NTDB_id=956534 UXQ75_RS09970 WP_000866106.1 2025198..2025872(-) (braR) [Staphylococcus aureus strain BSN76]
MKVLIVEDDLVIGKMLAEELKKWQLEPILIEGFNHVMDAFNTNAPELVLLDINLPAFNGYHWCQEIRKVSTVPIIFISSR
NDSMDQVMAMQMGADDFIEKPFNMTVTITKIQALLRRTYDFTTQVNNLTVDDCELLLDAAKLKFNEETIDLTHTELQIMH
SLFQNKGKFVSRNALIEKCWESEHFIDDNTLAVNITRLRKKLQKLGLTDFIETKKNVGYRVGDV

Nucleotide


Download         Length: 675 bp        

>NTDB_id=956534 UXQ75_RS09970 WP_000866106.1 2025198..2025872(-) (braR) [Staphylococcus aureus strain BSN76]
ATGAAAGTATTAATCGTAGAGGATGACTTAGTTATCGGGAAGATGCTTGCTGAAGAGCTCAAGAAGTGGCAGCTAGAACC
GATCTTAATAGAAGGTTTCAATCATGTAATGGATGCCTTCAACACGAATGCACCGGAACTTGTGTTACTCGATATTAATT
TACCTGCCTTCAATGGTTATCACTGGTGTCAGGAGATTCGTAAAGTTTCTACTGTACCGATTATATTTATTAGTTCGCGT
AACGACAGTATGGATCAAGTAATGGCGATGCAGATGGGTGCGGATGATTTCATTGAGAAGCCATTTAATATGACTGTTAC
AATTACTAAGATTCAAGCACTATTACGCCGCACGTATGATTTCACCACTCAAGTTAATAATTTAACAGTAGATGATTGCG
AGTTACTACTTGATGCAGCAAAGCTTAAATTTAATGAAGAAACCATAGACCTGACACACACTGAATTGCAAATCATGCAT
AGCTTATTCCAGAACAAGGGCAAATTCGTCAGTCGTAATGCGTTAATCGAAAAATGCTGGGAATCAGAACACTTCATTGA
TGACAATACGCTTGCTGTCAACATTACACGTTTACGCAAAAAGCTACAAAAACTAGGACTTACAGATTTTATCGAAACGA
AGAAAAATGTCGGATATCGTGTAGGTGACGTATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

66.516

98.661

0.656