Detailed information NTG0095465

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: QMM27_RS09220
• Genome accession: NZ_AP025939
• Coordinates: 1809447..1809908 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250539.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Utah_35B-24
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1804447..1814908

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QMM27_RS09185 (Utah35B_17920)	-	1804752..1805576 (-)	825	WP_000727909.1	membrane protein insertase YidC	-
QMM27_RS09190 (Utah35B_17930)	rnpA	1805551..1805922 (-)	372	WP_000739246.1	ribonuclease P protein component	-
QMM27_RS09195	-	1805939..1806070 (-)	132	WP_000768904.1	hypothetical protein	-
QMM27_RS09200 (Utah35B_17940)	-	1806071..1807261 (-)	1191	WP_000167769.1	acetate/propionate family kinase	-
QMM27_RS09205 (Utah35B_17950)	comYH	1807312..1808265 (-)	954	WP_000345080.1	class I SAM-dependent methyltransferase	Machinery gene
QMM27_RS09210	-	1808326..1808920 (-)	595	Protein_1797	methyltransferase domain-containing protein	-
QMM27_RS09215 (Utah35B_17980)	comGG/cglG	1809023..1809469 (-)	447	WP_001842224.1	competence type IV pilus minor pilin ComGG	Machinery gene
QMM27_RS09220	comGF/cglF	1809447..1809908 (-)	462	WP_000250539.1	competence type IV pilus minor pilin ComGF	Machinery gene
QMM27_RS09225 (Utah35B_18000)	comGE/cglE	1809871..1810173 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
QMM27_RS09230 (Utah35B_18010)	comGD/cglD	1810136..1810540 (-)	405	WP_000588030.1	competence type IV pilus minor pilin ComGD	Machinery gene
QMM27_RS09235 (Utah35B_18020)	comGC/cglC	1810533..1810859 (-)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
QMM27_RS09240 (Utah35B_18030)	comGB/cglB	1810861..1811877 (-)	1017	WP_078102766.1	competence type IV pilus assembly protein ComGB	Machinery gene
QMM27_RS09245 (Utah35B_18040)	comGA/cglA/cilD	1811825..1812766 (-)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
QMM27_RS09250 (Utah35B_18050)	-	1812842..1813207 (-)	366	WP_000286415.1	DUF1033 family protein	-
QMM27_RS09255 (Utah35B_18060)	-	1813358..1814416 (-)	1059	WP_000649470.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17851.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=95465 QMM27_RS09220 WP_000250539.1 1809447..1809908(-) (comGF/cglF) [Streptococcus pneumoniae strain Utah_35B-24]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=95465 QMM27_RS09220 WP_000250539.1 1809447..1809908(-) (comGF/cglF) [Streptococcus pneumoniae strain Utah_35B-24]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae D39	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae R6	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae TIGR4	94.118	100	0.941
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915