Detailed information NTG0095355

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: QMM10_RS06025
• Genome accession: NZ_AP025938
• Coordinates: 1192520..1193170 (-)
• Length: 216 a.a.
• NCBI ID: WP_001864147.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900701057
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1187520..1198170

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QMM10_RS06005 (PC1044_11820)	-	1188124..1189305 (-)	1182	WP_000655951.1	membrane protein	-
QMM10_RS06010 (PC1044_11830)	-	1189309..1189896 (-)	588	WP_000939886.1	ABC transporter ATP-binding protein	-
QMM10_RS06015 (PC1044_11840)	-	1189929..1190117 (-)	189	WP_050207196.1	hypothetical protein	-
QMM10_RS06020 (PC1044_11850)	comEC/celB	1190296..1192536 (-)	2241	WP_281962102.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
QMM10_RS06025 (PC1044_11860)	comEA/celA/cilE	1192520..1193170 (-)	651	WP_001864147.1	helix-hairpin-helix domain-containing protein	Machinery gene
QMM10_RS06030 (PC1044_11870)	-	1193238..1193807 (-)	570	WP_001864145.1	GNAT family N-acetyltransferase	-
QMM10_RS06035	ald	1193984..1195095 (+)	1112	Protein_1201	alanine dehydrogenase	-
QMM10_RS06040 (PC1044_11910)	-	1195396..1195722 (-)	327	Protein_1202	TfoX/Sxy family protein	-
QMM10_RS06045 (PC1044_11920)	-	1195725..1196225 (-)	501	WP_000566983.1	GNAT family N-acetyltransferase	-
QMM10_RS06050 (PC1044_11930)	-	1196418..1197386 (-)	969	WP_000658183.1	PhoH family protein	-
QMM10_RS06055 (PC1044_11940)	-	1197472..1197687 (-)	216	WP_001232082.1	YozE family protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23205.54 Da
• Isoelectric Point: 5.5171

>NTDB_id=95355 QMM10_RS06025 WP_001864147.1 1192520..1193170(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain PZ900701057]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQVEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=95355 QMM10_RS06025 WP_001864147.1 1192520..1193170(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain PZ900701057]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTCAAAGAAACGAATTTGCAGGTTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-214)

• SLBB domain (SLBB) (76-126)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae D39	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae R6	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	97.222	100	0.972
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.833	100	0.958
comEA/celA/cilE	Streptococcus mitis SK321	91.204	100	0.912
comEA	Lactococcus lactis subsp. cremoris KW2	43.612	100	0.458
comEA	Latilactobacillus sakei subsp. sakei 23K	33.906	100	0.366
comEA	Bacillus subtilis subsp. subtilis str. 168	41.579	87.963	0.366