Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACH6F1_RS06560 Genome accession   NZ_CP172397
Coordinates   1247778..1249592 (-) Length   604 a.a.
NCBI ID   WP_395941503.1    Uniprot ID   -
Organism   Campylobacter coli strain YH506     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1242778..1254592
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACH6F1_RS06535 (ACH6F1_06525) - 1243338..1243960 (-) 623 Protein_1266 hypothetical protein -
  ACH6F1_RS06540 (ACH6F1_06530) - 1244200..1244511 (+) 312 WP_002825152.1 hypothetical protein -
  ACH6F1_RS06545 (ACH6F1_06535) hemE 1244665..1245687 (+) 1023 WP_002825154.1 uroporphyrinogen decarboxylase -
  ACH6F1_RS06550 (ACH6F1_06540) - 1245684..1246586 (+) 903 WP_002825155.1 radical SAM protein -
  ACH6F1_RS06555 (ACH6F1_06545) - 1246583..1247776 (-) 1194 WP_002777493.1 hypothetical protein -
  ACH6F1_RS06560 (ACH6F1_06550) uvrC 1247778..1249592 (-) 1815 WP_395941503.1 excinuclease ABC subunit UvrC Machinery gene
  ACH6F1_RS06565 (ACH6F1_06555) - 1249585..1250061 (-) 477 WP_025399120.1 hypothetical protein -
  ACH6F1_RS06570 (ACH6F1_06560) guaA 1250198..1251733 (+) 1536 WP_025399121.1 glutamine-hydrolyzing GMP synthase -
  ACH6F1_RS06575 (ACH6F1_06565) - 1251908..1252516 (+) 609 WP_002783669.1 class I SAM-dependent methyltransferase -
  ACH6F1_RS06580 (ACH6F1_06570) - 1252639..1253197 (-) 559 Protein_1275 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 604 a.a.        Molecular weight: 69790.89 Da        Isoelectric Point: 9.1905

>NTDB_id=953288 ACH6F1_RS06560 WP_395941503.1 1247778..1249592(-) (uvrC) [Campylobacter coli strain YH506]
MTEILLKNTLKEELQTLPSNAGVYQYFNAEGKLLYVGKAKNLKNRVRSYFAFTPNLHANPKNSLRIQKMIEEVMHLEFIT
TNSEADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFNEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYP
LKQKASCKSPCIFYQISRCLAPCDKKITQEEYRLILDKAINALLSPSILVKKLEKQMLHLAQNENYEEAAKIRDQIATIR
DLEIKVEIDIAKLEDFEIFALACEGSMLSTLRFVVQNGKIISANSKITPLKNNTDFDKNEIYKQLILENFSIDIPLVTNT
IYVYEEFEDRELLEEILSQRFDKKISIKVPKIGEKRRICDLAFQNACLNIQKEQKNSDFNIQKELKNYFELENLPNCIEV
FDNSHMQGVANVGAMVAYKMGAWDKSNYRKFHLKYKNDYEQMREVLTRRALEFDKMPAPDLWLIDGGKALLDLAKEIILS
SGANVDILAISKEKINAKAHRAKGGAKDKIHSLKGEFALSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLSSSKLVK
SGLSAGVIQKLLAYYGSFEAIYEANFEELCQLVGKKSAQKIKED

Nucleotide


Download         Length: 1815 bp        

>NTDB_id=953288 ACH6F1_RS06560 WP_395941503.1 1247778..1249592(-) (uvrC) [Campylobacter coli strain YH506]
ATGACTGAAATTTTACTTAAAAACACTCTCAAAGAAGAGCTTCAAACTCTACCTTCAAATGCTGGAGTCTATCAGTATTT
TAACGCCGAAGGAAAACTTTTATATGTAGGCAAGGCTAAAAATCTTAAAAACCGAGTAAGATCTTATTTTGCTTTTACTC
CGAATTTGCATGCTAACCCAAAAAATTCTTTAAGAATTCAAAAAATGATAGAAGAAGTGATGCATTTGGAATTTATTACG
ACAAATTCAGAAGCTGATGCTTTGATTTTGGAAAATTCTTTTATCAAGCAACTTCATCCAAAATACAATATTTTATTAAG
AGATGATAAGACTTATCCTTATATTTATGTAGATTTTAATGAAGAATTCCCGCGTTTTGAAATCACTAGAAAATTAGTAA
AAAAGAGTAAAATTAAATATTTTGGTCCCTTTTTTAAAGGGGCTAGAGAGCTTTTAGATGCGCTTTATTTGTATTATCCA
TTAAAACAAAAAGCAAGTTGTAAATCTCCTTGTATTTTTTATCAAATTTCTCGTTGTCTTGCGCCTTGTGATAAAAAAAT
TACCCAAGAAGAATATCGTTTGATTTTAGATAAAGCTATCAATGCTCTTTTAAGTCCCAGTATTTTAGTGAAAAAATTAG
AAAAGCAAATGCTTCATTTAGCCCAAAATGAAAATTATGAAGAAGCGGCAAAAATAAGAGATCAGATTGCTACGATAAGG
GATTTGGAAATTAAAGTTGAGATTGATATTGCTAAATTAGAAGACTTTGAAATTTTTGCTTTAGCTTGTGAAGGCTCTAT
GCTTTCAACTTTGCGTTTTGTCGTGCAAAATGGAAAAATCATCAGTGCCAATTCTAAAATCACCCCACTTAAAAATAATA
CAGATTTTGATAAAAATGAGATTTATAAGCAACTTATTTTAGAAAATTTTAGCATAGACATTCCCTTGGTTACAAATACT
ATTTATGTTTATGAAGAATTTGAAGATAGGGAGCTTTTGGAAGAAATTTTAAGCCAAAGATTTGATAAAAAAATCAGTAT
TAAGGTTCCTAAAATAGGAGAAAAAAGAAGAATTTGTGATTTGGCATTTCAAAATGCGTGTTTGAATATACAAAAAGAGC
AAAAAAATAGTGATTTTAATATACAAAAAGAACTTAAAAATTATTTCGAGCTTGAAAATTTGCCAAATTGTATAGAGGTT
TTTGATAATTCTCATATGCAAGGTGTGGCGAATGTAGGAGCTATGGTAGCTTATAAAATGGGTGCTTGGGATAAGTCAAA
TTATAGAAAATTTCATTTAAAATACAAAAATGATTATGAGCAAATGCGTGAAGTTTTAACGCGTAGAGCATTAGAATTTG
ACAAAATGCCTGCTCCTGATTTGTGGCTTATAGATGGGGGAAAGGCTTTGCTTGATTTAGCTAAAGAAATCATCTTAAGT
AGTGGGGCAAATGTTGATATTTTAGCAATCTCAAAAGAAAAAATCAATGCTAAAGCTCACCGCGCTAAAGGAGGGGCTAA
AGATAAAATTCACTCTTTAAAAGGAGAATTTGCCCTAAGCATTAACGATAAAAAATTACAATTCTTACAGAAATTAAGAG
ATGAAGCACATCGTTTTGCCATAAGTTTTCATCAAAACACTAAGAAAAAACAAGATTTATCAAGCTCTAAGCTTGTAAAA
TCAGGACTTAGTGCGGGAGTTATACAAAAACTTTTGGCGTATTATGGAAGTTTTGAAGCTATTTATGAGGCAAATTTTGA
AGAATTGTGCCAATTAGTAGGAAAAAAATCAGCACAAAAAATAAAGGAAGATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(209-241)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(387-541)

GIY-YIG catalytic domain (GIY-YIG)

(21-103)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

46.154

96.854

0.447