Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACH6FV_RS02645 Genome accession   NZ_CP172391
Coordinates   532049..533863 (+) Length   604 a.a.
NCBI ID   WP_002786130.1    Uniprot ID   -
Organism   Campylobacter coli strain YH508     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 527049..538863
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACH6FV_RS02625 (ACH6FV_02625) - 528441..528998 (+) 558 WP_052779640.1 class I SAM-dependent methyltransferase -
  ACH6FV_RS02630 (ACH6FV_02630) - 529121..529733 (-) 613 Protein_509 class I SAM-dependent DNA methyltransferase -
  ACH6FV_RS02635 (ACH6FV_02635) guaA 529908..531443 (-) 1536 WP_349325238.1 glutamine-hydrolyzing GMP synthase -
  ACH6FV_RS02640 (ACH6FV_02640) - 531580..532056 (+) 477 WP_002777499.1 hypothetical protein -
  ACH6FV_RS02645 (ACH6FV_02645) uvrC 532049..533863 (+) 1815 WP_002786130.1 excinuclease ABC subunit UvrC Machinery gene
  ACH6FV_RS02650 (ACH6FV_02650) - 533865..535058 (+) 1194 WP_002777493.1 hypothetical protein -
  ACH6FV_RS02655 (ACH6FV_02655) - 535055..535957 (-) 903 WP_002777490.1 radical SAM protein -
  ACH6FV_RS02660 (ACH6FV_02660) hemE 535954..536976 (-) 1023 WP_002780202.1 uroporphyrinogen decarboxylase -
  ACH6FV_RS02665 (ACH6FV_02665) - 537124..537435 (-) 312 WP_002777486.1 hypothetical protein -
  ACH6FV_RS02670 (ACH6FV_02670) - 537657..538265 (+) 609 WP_002845092.1 hypothetical protein -

Sequence

Protein


Download         Length: 604 a.a.        Molecular weight: 69738.69 Da        Isoelectric Point: 9.1096

>NTDB_id=953136 ACH6FV_RS02645 WP_002786130.1 532049..533863(+) (uvrC) [Campylobacter coli strain YH508]
MAEILLKNTLKEELQTLPANAGVYQYFNAEGKLLYVGKAKNLKNRVRSYFAFTPNLRANPKNSLRIQKMIEEAVHLEFIT
TNSEADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFNEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYP
LKQKASCKSPCIFYQISRCLAPCDKKITQEEYRLILDKAINALLSPSILVKNLEKQMFHLAQNENYEEAAKIRDQIATIR
DLEIKVEIDIAKLEDFEIFALACESSMLSTLRFVVQNGKIISANSKITPLKNNTDFDKNEIYKQLILENFSVDIPLVANT
VYVYEDFEDRELLEEILSQRFDKKISIKVPKIGEKRRICDLAFQNACLNIQKEQKNSDFNIQKELKNYFELENLPNCIEV
FDNSHLQGVANVGAMITYKMGTWDKSNYRKFHLKYKNDYEQMREVLTRRALEFDKMPAPDLWLIDGGKALLDLAKEIILS
SGANVDILAISKEKIDAKAHRAKGGAKDKIHSLKGEFALSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLSSSKLVK
SGLSAGVIQKLLAYYGSFEAIYEANFEELCQLVGKKSAQKIKED

Nucleotide


Download         Length: 1815 bp        

>NTDB_id=953136 ACH6FV_RS02645 WP_002786130.1 532049..533863(+) (uvrC) [Campylobacter coli strain YH508]
ATGGCTGAAATTTTACTTAAAAATACTCTCAAAGAAGAGCTTCAAACCCTACCTGCAAATGCTGGAGTGTATCAGTATTT
TAATGCCGAAGGAAAGCTTTTATATGTAGGCAAGGCTAAAAATCTTAAAAACCGCGTAAGATCTTATTTTGCTTTTACCC
CAAATTTACGCGCCAATCCAAAAAATTCTTTAAGAATTCAAAAAATGATAGAAGAAGCGGTGCATTTGGAATTTATTACA
ACAAATTCAGAAGCTGATGCTTTGATTTTGGAAAATTCTTTTATCAAGCAACTTCATCCAAAATACAATATTTTACTAAG
AGATGATAAGACTTATCCTTATATTTATGTAGATTTTAATGAAGAATTTCCGCGTTTTGAAATCACTAGAAAATTAGTTA
AAAAAAGTAAAATCAAATATTTTGGCCCCTTTTTTAAAGGAGCTAGAGAGCTTTTAGATGCGCTTTATTTATACTATCCT
TTAAAGCAAAAAGCAAGTTGTAAATCTCCTTGTATTTTTTATCAAATTTCTCGTTGTCTTGCGCCTTGTGATAAAAAAAT
TACCCAAGAAGAATATCGTTTGATTTTAGATAAAGCTATCAATGCTCTTTTAAGCCCTAGTATTTTAGTGAAAAATTTGG
AAAAACAAATGTTTCATTTAGCCCAAAATGAGAATTATGAAGAAGCGGCAAAAATAAGAGATCAGATTGCTACGATAAGG
GATTTGGAAATTAAAGTTGAGATTGATATCGCTAAATTAGAAGACTTTGAAATTTTTGCTTTAGCTTGTGAAAGCTCTAT
GCTTTCAACTTTGCGTTTTGTGGTGCAAAATGGAAAAATCATCAGCGCTAATTCTAAAATCACTCCGCTTAAAAACAATA
CAGATTTTGATAAAAATGAGATTTATAAACAGCTTATTTTAGAAAATTTTAGCGTAGACATTCCTTTGGTTGCAAATACT
GTTTATGTTTATGAGGATTTTGAAGACAGGGAGCTTTTAGAAGAAATTTTAAGCCAGAGATTTGATAAAAAAATCAGCAT
TAAAGTTCCTAAAATAGGGGAAAAAAGAAGAATTTGTGATTTGGCATTTCAAAATGCGTGTTTAAATATACAAAAAGAGC
AAAAAAATAGTGATTTTAATATACAAAAAGAACTTAAAAATTATTTCGAGCTTGAAAATCTGCCAAATTGTATAGAAGTT
TTTGATAATTCTCATTTGCAAGGTGTGGCGAATGTAGGAGCTATGATAACTTATAAAATGGGTACTTGGGATAAGTCAAA
TTATAGAAAATTTCATTTAAAATACAAAAATGATTATGAGCAAATGCGTGAAGTTTTAACGCGTAGAGCATTAGAATTTG
ACAAAATGCCTGCTCCTGATTTGTGGCTTATAGATGGGGGAAAGGCTTTGCTTGATTTAGCTAAAGAAATCATCTTAAGT
AGTGGGGCAAATGTTGATATTTTAGCAATCTCAAAAGAAAAAATCGATGCTAAAGCTCACCGCGCTAAAGGAGGGGCTAA
AGATAAAATTCACTCTTTAAAAGGAGAATTTGCCCTAAGCATTAACGATAAAAAATTACAATTCTTACAGAAATTAAGAG
ATGAAGCACATCGTTTTGCCATAAGTTTTCATCAAAACACTAAGAAAAAACAAGATTTATCAAGCTCTAAGCTTGTAAAA
TCAGGACTTAGTGCGGGAGTTATACAAAAACTTTTGGCGTATTATGGAAGTTTTGAAGCTATTTATGAGGCAAATTTTGA
AGAATTGTGCCAATTAGTAGGAAAAAAATCAGCACAAAAAATAAAGGAAGATTGA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(21-103)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(387-541)

UvrB/uvrC motif (UVR)

(209-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

46.18

97.517

0.45