Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACH6FD_RS06485 Genome accession   NZ_CP172362
Coordinates   1247364..1249166 (-) Length   600 a.a.
NCBI ID   WP_002875857.1    Uniprot ID   -
Organism   Campylobacter jejuni strain YH022     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1242364..1254166
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACH6FD_RS06460 (ACH6FD_06460) - 1242489..1243688 (+) 1200 WP_002853994.1 MFS transporter -
  ACH6FD_RS06465 (ACH6FD_06465) ciaC 1243744..1244064 (+) 321 WP_002853224.1 invasion antigen CiaC -
  ACH6FD_RS06470 (ACH6FD_06470) hemE 1244248..1245270 (+) 1023 WP_002859305.1 uroporphyrinogen decarboxylase -
  ACH6FD_RS06475 (ACH6FD_06475) - 1245267..1246169 (+) 903 WP_002853556.1 radical SAM protein -
  ACH6FD_RS06480 (ACH6FD_06480) - 1246166..1247362 (-) 1197 WP_002854153.1 hypothetical protein -
  ACH6FD_RS06485 (ACH6FD_06485) uvrC 1247364..1249166 (-) 1803 WP_002875857.1 excinuclease ABC subunit UvrC Machinery gene
  ACH6FD_RS06490 (ACH6FD_06490) - 1249159..1249653 (-) 495 WP_002867358.1 hypothetical protein -
  ACH6FD_RS06495 (ACH6FD_06495) guaA 1249792..1251327 (+) 1536 WP_002873151.1 glutamine-hydrolyzing GMP synthase -
  ACH6FD_RS06500 (ACH6FD_06500) - 1251414..1252874 (+) 1461 WP_002875858.1 hypothetical protein -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69703.76 Da        Isoelectric Point: 9.3844

>NTDB_id=952403 ACH6FD_RS06485 WP_002875857.1 1247364..1249166(-) (uvrC) [Campylobacter jejuni strain YH022]
MIKENLENELKTLPNSAGVYQYFNQEGKLLYVGKAKNLKNRVKSYFAFTPNLHANPRNSLRIQKMIEETVHLEFIATNSE
ADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFEEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYPLKQK
ASCKSPCIFYQISRCLAPCDKLISREKYLEILDEAIHALLNPSVLLKNLEKQMLVLAQNENYEEAAKVRDQIAMIKDLEV
KVEIDIAKLEDFEVFALAFKNSVLSTLRFVVQNGKIISANSKITPIRNDIQWDQNEIYKQLILENFSMDIPLLANVIYVY
EEFEDRVLLEEILSQRFDKKISIKIPKIGEKRRICDLAFQNALLNIEKEQKNHDFTIQKELKFYFELENLPNDIEIFDNS
HLQGVANVGAMVTYRINSWDKSKYRKFHLKHKNDYDQMREVLTRRALDFDKIPPPDLWLIDGGKALLDLAKEIIVSSGAN
VDILAISKEKIDAKAHRAKGGAKDKIHSLKGEFSLSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLNSSKLVNLGLS
SGVIQKLLAYYGNFESIYKADFKDLTMLVGRKAAQKIKEN

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=952403 ACH6FD_RS06485 WP_002875857.1 1247364..1249166(-) (uvrC) [Campylobacter jejuni strain YH022]
TTGATTAAAGAGAATTTAGAAAATGAGTTAAAAACTCTTCCCAATAGTGCTGGAGTGTATCAATATTTTAATCAAGAAGG
AAAGCTTTTATATGTAGGCAAGGCTAAAAATCTTAAAAATCGTGTCAAATCTTATTTTGCCTTTACTCCAAATTTACATG
CAAATCCAAGAAATTCTTTAAGAATTCAAAAAATGATTGAAGAAACAGTGCATTTGGAATTTATTGCTACTAATTCAGAG
GCTGATGCTTTGATTTTAGAAAATTCTTTTATCAAACAACTGCATCCAAAATATAATATTTTGCTAAGAGATGATAAAAC
TTATCCTTATATTTATGTGGATTTTGAAGAAGAATTTCCACGCTTTGAGATCACTAGAAAATTAGTAAAAAAAAGCAAAA
TTAAATATTTTGGCCCTTTTTTTAAAGGCGCTAGAGAGCTTTTAGATGCGCTTTATTTATACTATCCTTTAAAGCAAAAA
GCAAGTTGTAAATCCCCTTGTATTTTTTATCAAATTTCTCGTTGTCTTGCACCTTGTGATAAACTCATCAGCAGGGAAAA
ATACCTTGAAATTTTAGATGAGGCTATACACGCACTTTTAAATCCTAGTGTTTTGCTTAAAAACTTAGAAAAACAAATGC
TTGTTTTAGCACAAAATGAAAATTACGAAGAAGCAGCTAAAGTAAGAGATCAGATTGCAATGATTAAAGATTTGGAAGTT
AAGGTTGAAATAGATATTGCGAAATTAGAAGATTTTGAAGTATTTGCTTTAGCTTTTAAAAATTCCGTGCTTTCAACCTT
GCGTTTTGTGGTGCAAAATGGAAAAATTATCAGTGCAAATTCTAAGATTACTCCTATAAGAAATGATATACAATGGGATC
AAAATGAAATTTATAAGCAACTGATTTTAGAAAATTTTAGCATGGATATTCCTTTGCTTGCAAATGTTATTTATGTTTAT
GAAGAATTTGAAGATAGAGTGCTTTTAGAAGAAATTTTAAGCCAAAGGTTTGATAAAAAAATCAGTATTAAAATCCCTAA
AATAGGAGAAAAAAGAAGAATTTGTGATTTGGCTTTTCAAAATGCCCTTTTAAATATAGAAAAAGAGCAAAAAAATCATG
ATTTTACTATACAAAAAGAATTAAAGTTTTATTTTGAGCTTGAAAATTTACCAAATGATATAGAAATTTTTGACAATTCT
CATTTGCAAGGCGTGGCAAATGTTGGAGCTATGGTAACTTATAGAATAAATTCTTGGGATAAGTCAAAATATAGAAAATT
TCATTTAAAACATAAAAATGACTATGATCAAATGCGTGAAGTTTTAACGCGTAGAGCTTTGGACTTTGATAAAATACCTC
CTCCTGATTTATGGCTTATAGATGGGGGAAAGGCTTTGCTTGATTTGGCTAAAGAAATCATTGTAAGTAGTGGGGCAAAT
GTCGATATTTTAGCTATTTCAAAAGAAAAAATCGATGCAAAAGCACATAGAGCTAAAGGGGGTGCTAAGGATAAAATTCA
TTCCTTAAAAGGAGAATTTAGTCTAAGCATTAACGATAAAAAACTACAATTCTTACAGAAATTAAGAGATGAAGCACACC
GTTTTGCTATCAGCTTTCATCAAAATACTAAGAAAAAACAGGACTTGAATAGTTCTAAGCTTGTAAATTTAGGACTTAGT
TCAGGGGTTATACAAAAACTTTTAGCGTATTATGGAAATTTTGAATCTATATATAAGGCTGATTTTAAAGATCTTACAAT
GCTTGTAGGCAGGAAAGCGGCGCAAAAGATAAAGGAAAATTGA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-537)

GIY-YIG catalytic domain (GIY-YIG)

(18-99)

UvrB/uvrC motif (UVR)

(205-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

47.079

97

0.457